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TransCure bioServices SAS
TransCure bioServices SAS is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country.
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Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody Isotype Switching Modify antibody isotypes from any species to any human IgG isotype.
Bioimaging
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Biomarkers
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
Cell Culture and Characterization
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Resin-based Histology Perform sectioning and histological analysis of epoxy/acrylic/polycarbonate-embedded samples.
- Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.
Chemical and Compound Analysis
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Show all 73 services
Companion Diagnostics
- Pancreatic Cancer CDx Design and validate companion diagnostics for pancreatic cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Disease Models
- Acute Liver Failure Models Measure therapeutic endpoints in animal models of acute liver failure.
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Autoimmune Models Measure therapeutic endpoints in animal models with autoimmune disorders.
- Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
- Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
Show all 20 in Disease Models
- Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
- Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
- Liver Disease Animal Models Measure therapeutic endpoints in animal models with liver disease.
- Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
- Osteoarthritic Pain Models Measure therapeutic endpoints in animal models of osteoarthritic pain.
- OVA Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
- Systemic Lupus Erythematosus Models Measure therapeutic endpoints in animal models of immune disorders such as SLE and lupus.
- Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.
- Xenografts Evaluate drug candidate in tissue graft or organ transplant model.
Farm & Livestock Solutions
- Processing Techniques Investigation of mechanisms and kinetics of specific reactions for the improvement and stability of bioactive compounds.
General in vivo Toxicology
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
In Vitro ADME
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
In Vitro Assays
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
- ELISpot Assay and Testing Detect low levels of antigens.
- Human Immuno-deficiency Virus Infection CDx Design and validate companion diagnostics for HIV infection that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
- Immunofocus™ Predict the response to anti PD1/PDL1 directed therapies.
In Vitro Pharmacology
- B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
- Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.
- HuGEMM - Immuno-Oncology Model Evaluate human-specific therapeutics for checkpoint inhibitors, including anti-human PD-1, anti-human PDL-1, and anti-human CTLA-4 antibodies.
- Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
- Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
- Programmed Death-Ligand 2 (PD-L2) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of PD-L2 ligand.
Show all 7 in In Vitro Pharmacology
- Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.
In Vitro Toxicology
- Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
- Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
- SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
- SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
- Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
Oncology Models
- Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
- CAR-T Efficacy In Vivo assessment of CAR-T and CAR-NK efficacy in a humanized mouse
- NCG Model Study tumor biology and immuno-oncology in the CRISPR/Cas9-generated immunodeficient mouse model.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
- Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
Show all 8 in Oncology Models
- Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Safety Pharmacology
- Cytokine Release Syndrome In Vivo assessment of cytokine release syndrome liability in a humanized mouse
- Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
- Respiratory Toxicology Assess difficulty breathing, altered respiration, blood gas changes and blood pH issues due to adverse reactions.
Scientific Data Services
- Cancer Systems Biology Convert complex molecular data obtained from high-throughput technologies to deducible information.
Other services
- Human Dendritic Cell (hDC) Model Test and validate the immune-modulating compounds in DC immune pathway models.
- New Request
Where it operates
Sites by country, with the cities in each.
-
France 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Fee-for-Service full human immune system mouse models for Immuno-Oncology, HIV, Inflammation, Vaccine, PDX, Autoimmune diseases
- Website
- www.tcbioservices.com
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