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Research supplier
Prestwick Chemical
Prestwick Chemical is listed as a small business research supplier in the Scientist.com network, with 4 sites in 2 countries and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
Show all 12 in Discovery Chemistry
- Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
- HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Service areas:
Where it operates
Sites by country, with the cities in each.
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France 3 sites
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Prestwick Chemical is a drug discovery CRO that successfully optimizes hit compounds into clinical development candidates. With our premium partners, we offer fully integrated drug discovery research services: Hit identification and validation, hit to lead expansion, lead optimization and profiling. These approaches are initially supported by advanced computer-aided molecular design and large-scale virtual screening capabilities. Prestwick Chemical smart screening libraries and internal chemistry expertise lend further support to the projects to address activity, selectivity and ADME/TOX...
Show the full description
Prestwick Chemical is a drug discovery CRO that successfully optimizes hit compounds into clinical development candidates. With our premium partners, we offer fully integrated drug discovery research services: Hit identification and validation, hit to lead expansion, lead optimization and profiling. These approaches are initially supported by advanced computer-aided molecular design and large-scale virtual screening capabilities. Prestwick Chemical smart screening libraries and internal chemistry expertise lend further support to the projects to address activity, selectivity and ADME/TOX issues.
Founded in 1999 by Prof. C. G. Wermuth, a renowned expert in medicinal chemistry, Prestwick’s experienced team of medicinal chemists develops and implements innovative strategies tailored to the client’s needs with unprecedented success: 6 Prestwick compounds are currently in clinical development, from Phase 1 to Phase 3.
- Website
- www.prestwickchemical.com
Work with Prestwick Chemical on Scientist.com
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