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RxCelerate Ltd
RxCelerate Ltd is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.
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Sites
1
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Show all 17 in Biomarkers
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Interferon Gamma Release Assay Use in vivo or in vitro assays to measure the cell-mediated immune response to an infectious agent.
- Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
Chemical and Compound Analysis
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Clinical Consulting
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Show all 64 services
Commercial Consulting
- Portfolio Management Manage a portfolio of projects in early-stage drug discovery and provide factors that determine the success of the proposed portfolio.
Data Science/Bioinformatics
- In Silico Drug-Drug Interactions Use computational tools to predict pharmaceutical, pharmacodynamic or pharmacokinetic drug-drug interactions to maximize drug regimen safety.
- In Silico Pro-drug Predictions Use computer simulation to assess pro-drug absorption and conversion to predict pharmacokinetic properties.
- In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.
Discovery Chemistry
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Disease Models
- Bone Models Measure therapeutic endpoints in animal models of bone disorders.
- Osteoarthritic Pain Models Measure therapeutic endpoints in animal models of osteoarthritic pain.
- Osteoporosis Models Measure therapeutic endpoints in animal models of osteoporosis.
In Vitro Assays
- Anti-thrombin Assays Use clotting and chromogenic assays to detect and classify anti-thrombin deficiency.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Assay Development Construct or create new assays or modify existing ones.
- Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Show all 13 in In Vitro Assays
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Thrombin Generation Tests Measure the tendency of a plasma sample to form thrombin upon the initiation of coagulation.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- Pulmonary Hypertension Animal Model Study the pathology of pulmonary arterial hypertension (PAH) and investigate potential therapies.
- Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
Protein Sciences
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
- Protein Binding Determine drug-protein binding interactions
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
Show all 9 in Protein Sciences
- Protein Post-translational Modification Analysis Measure glycosylation, phosphorylation, sulfation, ubiquitination, methylation and acetylation.
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Scientific Data Services
- Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
- Metabolomics Data Analysis Use metabolites to identify any potential biomarkers or novel therapeutic targets that may play a role in the mechanisms responsible for the progression of a disease.
- Omics Informatics Consulting Services for the analysis of large-scale molecular data sets.
- Systems Biomedicine Analyze complex interactions in biological systems with interdisciplinary scientific teams.
- Systems Network Analysis Analyze and visualize molecular pathways including gene regulatory, protein-protein and drug-target networks.
Service areas:
Biology
Where it operates
Sites by country, with the cities in each.
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United Kingdom 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Total Scientific provides biomarker discovery, assay development, and biostatistics.
- Website
- www.rxcelerate.com
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