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MicroCombiChem

MicroCombiChem is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Agricultural Sciences Research & Development

  • General Agrochemical Compound Library Find potential compound candidates for agrochemical or agro-product research and development.

Chemical and Compound Analysis

  • Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
  • Chiral Separation Purify therapeutically active isomers of drug candidates.
  • Compound Integrity Analyze the identity and purity of small molecule drug candidates.
  • High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
  • Liquid Chromatography Separate substances using a mobile and stationary phase.
  • MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Show all 12 in Chemical and Compound Analysis 6 more
  • NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
  • NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
  • Solution Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solution samples.
  • Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
  • Structural Spectroscopy Assess conformational transitions that proteins undergo in response to changes in their environment.
  • Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.

Chemistry, Manufacturing and Controls (CMC)

  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

Discovery Chemistry

  • Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
  • Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
  • HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Show all 8 in Discovery Chemistry 2 more
  • Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
  • Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.

Service areas:

Chemistry

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Germany Halsenbach 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

MicroCombiChem is focused on the synthesis of complex heterocyclic compounds with scaffolds and qualities expressing the demands for today's pharmaceutical and agrochemical research. Screening libraries, single rare chemicals as well as building blocks for further syntheses are produced by state-of-the-art chemistry methods. The compound libraries are developed and synthesized by applying defined parallel syntheses from combinatorial chemistry methods. The production is performed in small scales (milligram to gram) with possible upscaling to kilograms in cooperation with partners on-site...

Show the full description

MicroCombiChem is focused on the synthesis of complex heterocyclic compounds with scaffolds and qualities expressing the demands for today's pharmaceutical and agrochemical research.

Screening libraries, single rare chemicals as well as building blocks for further syntheses are produced by state-of-the-art chemistry methods. The compound libraries are developed and synthesized by applying defined parallel syntheses from combinatorial chemistry methods.

The production is performed in small scales (milligram to gram) with possible upscaling to kilograms in cooperation with partners on-site. HPLC-MS/NMR is a standard feature for the analytics, while the services include custom synthesis and preparation of the samples according to the customer's request.

Website
www.microcombichem.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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