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Laboratoire BIO-EC

Laboratoire BIO-EC is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Small business

Bioimaging

Bioimaging Visualize biological process non-invasively in real time.
Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

Adipogenesis Assay Detect and quantify intracellular triglyceride accumulation in adipocytes.
Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.

Show all 18 in Biomarkers 12 more

Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Lipid Peroxidation Assay Use in vitro or in vivo assays to evaluate the effects of oxidative stress on lipid structure and function.
Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
TUNEL Assay Detect in situ DNA fragmentation.
Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.

Cell Culture and Characterization

Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Lab On The Skin - The Sweat Analysis Platform Use a skin-like microfluidic wearable device to measure sweat production in response to exercise.
Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.

Show all 118 services 105 more

Chemical and Compound Analysis

Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
Ion Exchange Chromatography Separate and detect analytes.
Liquid Chromatography Separate substances using a mobile and stationary phase.
Photostability Measure drug degradation rates after exposure to various light sources.

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Phototoxicity & Photosensitization Test Test the potential for a product to elicit a reaction under UV exposure.
Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Raman Spectroscopy Use spectroscopic technique to observe vibrational, rotational and other low-frequency modes in a system.
UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.

Chemical and Compound Testing

USP <2021> Microbial Enumeration Tests Estimate the total aerobic microbial count, total combined yeast and mold counts, and the presence of bile-tolerant gram-negative bacteria present in nutritional supplements.
USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.

Chemistry, Manufacturing and Controls (CMC)

Anticaries Active Ingredients Acquire anticaries active ingredients for making oral health care products.
Oxidizers/Bleaches Acquire oxidizers/bleaches, such as hydrogen peroxide and sodium hypochlorite, to use as ingredients in consumer healthcare products.
Plant Extracts Acquire plant extracts, such as lutein, lycopene, and quinine, to use as ingredients in consumer healthcare products.
Subcellular Fraction Test System Obtain human, minipig, mouse, or rat dermal microsomes as in-stock standard test systems for the development of safer topical and transdermal products.

Clinical Consulting

Clinical Trial Recruitment Recruitment, enrollment and retention of patients for clinical trials.

Clinical Trials

Clinical Research Services Determine the safety and effectiveness of medications and medical devices.
Consumer Healthcare Product Trials Conduct clinical research to ensure the safety and efficacy of consumer healthcare products used for oral care, skin care, nutrition, and hair care.

Discovery Chemistry

LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.

Disease Models

Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
Hair Growth Models Measure dermal histology, skin thickness, % anagen induction, hair proliferation and other hair growth markers.
Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.

DNA & RNA

ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
DNA Sequencing Determine the nucleotide sequence of DNA samples.
Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
qPCR Analysis Measure the accumulation of PCR products in real time.
Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.

Show all 14 in DNA & RNA 8 more

RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
RNA Sequencing/Resequencing Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.
Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.
Whole Genome Sequencing Determine the entire genetic make-up of an organism.

Human Biological Samples

Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.

In Vitro Assays

Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Apoptotic Cell Staining Detect apoptotic cells in culture.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro SPF (Sun Protection Factor) Testing Use in vitro test methods to measure the UVA protection performance of sun protection products.
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Lipolysis Measure the hydrolysis of triglycerides into glycerol and free fatty acids.

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Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
Microbiology Study microbes and their role in human health.
Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation
Short Time Exposure (STE) Test Use in vitro eye irritation tests to assess cytotoxicity in SIRC cells (rabbit corneal cell line).

Protein Sciences

Cytokines Find recombinant cytokines or cytokine assays.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

Raw Materials

Antimicrobial Active Ingredients Acquire antimicrobial active ingredients for making consumer healthcare products.
Conditioners & Emollients (Hair & Skin Care) Acquire conditioners and emollients to use as ingredients in consumer healthcare products.
Oral Discomfort Relief Active Ingredients Acquire oral discomfort relief active ingredients for making consumer healthcare products.
Oral Health Care Product Ingredients Acquire ingredients for making oral healthcare products.
Topical Alcohol Ingredients Acquire isopropyl alcohol as an ingredient for making consumer healthcare products.
U.V. Absorbers Acquire U.V. absorbers, such as phenylbenzimidazole sulphonic acid and trolamine salicylate, to use as ingredients in consumer healthcare products.

REACH Services

REACH Services Assist in the registration, evaluation and authorization of chemical substances.

Scientific Data Services

In Silico Genomics/Transcriptomics Data Analysis Interpret DNA sequencing and microarray data.
In Silico Metagenomics/Metatranscriptomics Data Analysis Use software to analyze genomic information from multiple environmental sources.
Metagenomics Data Analysis Deconvolute the genetic content of genomes contained in environmental samples by utilizing whole genome sequencing techniques to provide insight into microbial communities and host phenotypes.
Microbiome Data Analysis Determine the population composition of a microbial community and analyze its contribution to human or animal health.

Testing Services

ASTM E1207: Antiperspirant Clinical Testing Determine antiperspirant efficacy for products (e.g. deodorant) that are intended to be applied to the underarm.
Bacterial Identification Testing Use biochemical and molecular methods to identify unknown microorganisms.
CLSI M26-A: Minimum Bactericidal Concentration (MBC) Determine the lowest concentration of an antimicrobial agent that is lethal to the target bacteria in vitro.
Collagen Production Test Test the regenerative ability of the skin under the influence of the test sample.
Cosmetic Preservative Efficacy Test Assess the efficacy of a product's preservative system.
Cosmetics Aerobic Plate Count Determine the level of aerobic bacteria present in a cosmetic or personal care product.

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Cosmetics Anaerobic Plate Count Determine the level of anaerobic bacteria present in a cosmetic or personal care product.
Cosmetics Yeast and Mold Count Determine the presence of fungi in a cosmetic or personal care product.
Human Eye Instillation Test Assess the eye irritation potential of a product compared with a marketed control product.
Human Repeat Insult Patch Test (HRIPT) Examples of which include Topical Irritation, Allergenicity, Phototoxicity and Photoallergy testing.
In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
ISO 11930: Preservative Test Evaluate the antimicrobial stabilization of a cosmetic product as per ISO 11930.
Microbiological Sterility Testing Test the presence of viable microorganisms.
Non-Acnegenicity & Non-Comedogenicity Test Test whether a cosmetic product is likely to cause acne and comedones (pimples).
Ocular Irritation Test Use human subjects to determine whether a cosmetic product or ingredient can cause ocular irritation.
OECD 435: Skin Corrosion Test - Membrane Barrier Method Use in vitro models to determine whether a cosmetic product or ingredient can cause skin corrosion.
Photoallergy Maximization Test Determine the photoallergenic potential of a topically applied product under maximization conditions.
Repeat Insult Patch Tests: Sensitisation Perform 100- and 200-subject patch tests to investigate sensitization (allergy) potential of a product following repeated exposure and challenge at a naïve skin site.
Sebum Production Testing to evaluate the oil production in the skin
Single Ocular Instillation Test Determine if a “tear-free” claim can be substantiated for a cosmetic product.
Skin Elasticity Testing Measure the skin's ability to resist pressure (firmness) and its ability to return to its original position pre- and post-treatment.
Skin Lightening Product Test Measure qualitative and quantitative changes in skin pigmentation under the influence of the test sample.
Stain Removal & Whitening Studies Assess the stain removal effectiveness of a tooth whitening product in healthy volunteers.
Tolerance Test Under Dermatologic Control Evaluate the acceptability and skin tolerance of a cosmetic product.
Trans-Epidermal Water Loss (TEWL) Use a sensing electrode encased in a chimney to measure the relative humidity percentage at the skin surface.
USP 51 Cosmetic Preservative Efficacy Test Evaluate the antimicrobial stabilization of a cosmetic product as per USP 51.
USP <62> Microbial Limits Test Determine the presence or absence of specific microorganisms.

Other services

Labskin - 3D Skin Model Obtain a full-thickness human skin model.

Website: www.bio-ec.fr

France Longjumeau, Saulx-les-Chartreux 2 sites

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