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Research supplier
Atuka
Atuka is listed as a small business research supplier in the Scientist.com network, with 3 sites in 2 countries and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- Magnetic Resonance Imaging Use MRI to obtain chemical and physical information about molecules and map the internal structure of an object.
- SPECT-CT and PET-CT Imaging Get images that combine the spatial context of metabolic or biochemical activity with an anatomic image.
Chemical and Compound Analysis
- Chemical Stability Measure the stability of small molecules in solution.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
Show all 7 in Chemical and Compound Analysis
- Photostability Measure drug degradation rates after exposure to various light sources.
Chemistry, Manufacturing and Controls (CMC)
- Analytical Development and Validation Request services related to Analytical Development and Validation
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
Show all 40 services
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
- Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
Show all 10 in Discovery Chemistry
- Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
- QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
- UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Disease Models
- Behavioral Testing Models Investigate sensory-motor and emotional functions, social behavior and day-night activity.
- Cognition Models Measure therapeutic endpoints in animal models of cognition.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
In Vitro Assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
- Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
Safety Pharmacology
- CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
- Implanted Telemetry Study - Monkey / Non-human Primate Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in monkeys/non-human primates.
- Jacketed External Telemetry (JET) Study - Monkey / Non-human Primate Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in monkeys/non-human primates.
- Locomotor Activity Assessment Study - Rat Conduct a study to determine the psychostimulant or sedative activity or your compound in rats.
- Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Show all 8 in Safety Pharmacology
- Safety Pharmacology Latin Square Study - Monkey / Non-human Primate Conduct a safety pharmacology study with a Latin square design in monkeys/non-human primates.
- Safety Pharmacology Study with Functional Observational Batteries (FOBs) - Other Species Conduct a safety pharmacology study with functional oberservational batteries in other species.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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Canada 2 sites
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China 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Atuka can deliver a range of contract research and consultancy services which cover the following broad categories: Assessment of pre-clinical efficacy in a range of rodent and primate disease models. These include efficacy testing with behavioural measures including motor and non-motor tests (e.g. cognition, sleep and impulsivity)in addition to a full range of post-mortem measures. DMPK (including all in-vivo and bioanalytical processes). In-vivo imaging (PET, MRI, CT). Consultancy services. Medicinal chemistry services including synthetic route and in-silico design, custom synthesis...
Show the full description
Atuka can deliver a range of contract research and consultancy services which cover the following broad categories:
- Assessment of pre-clinical efficacy in a range of rodent and primate disease models. These include efficacy testing with behavioural measures including motor and non-motor tests (e.g. cognition, sleep and impulsivity)in addition to a full range of post-mortem measures.
- DMPK (including all in-vivo and bioanalytical processes).
- In-vivo imaging (PET, MRI, CT).
- Consultancy services.
- Medicinal chemistry services including synthetic route and in-silico design, custom synthesis, chemical procurement, lead characterisation and preformulation.
- Website
- www.atuka.com
Work with Atuka on Scientist.com
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