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Biopta
Biopta is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 3 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Discovery Chemistry
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
Disease Models
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Comparative Pharmacology Compare drug responses across species for improved reliability in translational studies.
- Hair Growth Models Measure dermal histology, skin thickness, % anagen induction, hair proliferation and other hair growth markers.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Show all 13 in Disease Models
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
- Myocardial Infarction Models Measure therapeutic endpoints in animal models of myocardial infarction.
- Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
- Precision Cut Lung Slices (PCLS) Use a phenotypically accurate model of lung behavior for screening and target validation.
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
- Skin Graft Models Measure therapeutic endpoints in animal models of skin grafts.
DNA & RNA
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Human Biological Samples
- Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
- Tissue Acquisition Find primary animal and human tissues and cells.
In Vitro ADME
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
- Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
Show all 47 services
In Vitro Assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
In Vitro Pharmacology
- Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
- Chloride Channel Assays Use biochemical, cell-based or in vivo assays to measure chloride channel activity.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
Show all 8 in In Vitro Pharmacology
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
Model Development
- Animal Precision-Cut Lung Slice Model Acquire a fresh phenotypically-accurate model to study animal lung behavior.
- Fresh Functional Human Tissue Contractile Force Assays Use fresh functional human tissue to assess contractile force with various compounds.
- Fresh Functional Human Tissue Efficacy Assays Use fresh functional human tissue to assess pre-clinical efficacy of test compounds.
- Fresh Functional Human Tissue Ion Channel Activity Assays Use fresh functional human tissue to assess ion channel activity with various compounds.
- Fresh Functional Human Tissue Muscle Contraction Assays Use fresh functional human tissue to assess muscle contraction with various compounds.
- Fresh Functional Human Tissue Muscle Relaxation Assays Use fresh functional human tissue to assess muscle relaxation with various compounds.
Show all 12 in Model Development
- Fresh Functional Human Tissue Permeability Assays Use fresh functional human tissue to assess tissue permeability with various compounds.
- Fresh Functional Human Tissue Safety Assays Use fresh functional human tissue to assess pre-clinical safety of test compounds.
- Fresh Functional Human Tissue Vascular Permeability Assays Use fresh functional human tissue to assess vascular permeability with various compounds.
- Fresh Functional Human Tissue Vasoconstriction Assays Use fresh functional human tissue to assess vasoconstriction with various compounds.
- Fresh Functional Human Tissue Vasodilation Assays Use fresh functional human tissue to assess vasodilation with various compounds.
- Human Precision-Cut Lung Slice Model Acquire a fresh phenotypically-accurate model to study human lung behavior.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
Safety Pharmacology
- CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
- Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Testing Services
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United Kingdom 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
p<>. Based in Glasgow, UK, Biopta has been providing contract research services to the pharmaceutical industry since 2002 and has established itself as the world leader in the use of fresh, functional human tissues for prediction of drug safety, efficacy and absorption. p<>. Biopta offers GLP-compliant in vitro services in a wide range of ethically-obtained fresh human tissues and will work with you to design a bespoke service that creates valuable human data. Evidence that your compound is safe and efficacious in human tissue adds commercial value and confidence to your compounds...
Show the full description
p<>. Based in Glasgow, UK, Biopta has been providing contract research services to the pharmaceutical industry since 2002 and has established itself as the world leader in the use of fresh, functional human tissues for prediction of drug safety, efficacy and absorption.
p<>. Biopta offers GLP-compliant in vitro services in a wide range of ethically-obtained fresh human tissues and will work with you to design a bespoke service that creates valuable human data. Evidence that your compound is safe and efficacious in human tissue adds commercial value and confidence to your compounds and reduces the risk of late-stage failure. Biopta's services offer a cost-effective way to obtain human data prior to clinical studies, or to understand mechanisms underlying clinical observations, in particular when the clinical observations do not match the findings from pre-clinical animal models.
We provide services and testing on isolated or functional human tissue for:
- Coronary Arteries and Blood Vessels
- in vitro Genitourinary - bladder, ureter, prostate, or urethra
- Uterine Assays
- Acute Skin Inflammation
- Gastointestinal permeability - stomach, duodenum, jejunum, ileum, colon
- Mucosal Transport in the Lung and GI
- in vitro Lung and Lung Inflammation Assays
- Psoriasis-like Epidermal Hyperplasia
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Biopta Corporate Brochure
Biopta Frequently Asked Questions
- Website
- www.biopta.com
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