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Research supplier
Molecular Response
Molecular Response is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
DNA & RNA
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
Human Biological Samples
- Custom PDX models For requesting Custom PDX models
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human DNA Acquire human DNA.
- Human RNA Acquire fresh/frozen Human RNA based on patient demographics, disease stage, treatment and history.
In Vitro ADME
- Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Molecular Response is an oncology-focused CRO, with a viable primary tumor bank of more than 140,000 clinical biopsies, spanning 76 diagnoses. Tumors are employed to create Patient-Derived Xenograft (PDX) models, 3D cell culture for ex-vivo pharmacology studies, and genomic surveys for target prevalence. Tumors have histology/pathology reports, ex-vivo drug resistance data and matched FFPE blocks. These platforms allow for in vivo and ex-vivo drug candidate selection, patient stratification, biomarker verification, and development of Companion Diagnostic assays in CAP/CLIA-accredited labs.
- Professional associations
- BIOCOM
- Website
- molecularresponse.com
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