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CeeTox

CeeTox is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 2 service areas.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Discovery Chemistry

  • Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...

Disease Models

  • Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
  • Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
  • Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.

Drug Development

  • Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.

In Vitro ADME

  • Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
  • Nasal Permeability Test for passive diffusion and active transport in nasal permeability models.
  • Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
  • Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
  • Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.

In Vitro Assays

  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression

In Vitro Pharmacology

  • In Vitro Bone Models Measure osteoclast activity and bone formation in human or rat osteoclasts.
  • In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
  • In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
Show all 24 services 10 more

In Vitro Toxicology

  • Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
  • Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.

Other Specialty Toxicology

  • Phototoxicity Determine whether drug treatment causes light-activated toxic effects.

Protein Sciences

  • Protein Binding Determine drug-protein binding interactions

Specialty Dosing Routes

  • Dermal Toxicology Assess toxicity in rodent dermal testing models.
  • Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.

Testing Services

  • In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.

Other services

  • New Request  

Service areas:

Toxicology Biology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Kalamazoo 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

CeeTox offers in vitro toxicity screening, HTS, and in vitro assays.

Website
www.ceetox.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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