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HFR Chemistry

HFR Chemistry is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 3
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Chemical and Compound Analysis

  • Chemical Stability Measure the stability of small molecules in solution.
  • Chiral Separation Purify therapeutically active isomers of drug candidates.
  • Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
  • NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
  • Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.

Chemistry, Manufacturing and Controls (CMC)

  • Advanced intermediates Sourcing advanced intermediates
  • API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
  • Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
  • GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
Show all 8 in Chemistry, Manufacturing and Controls (CMC) 2 more
  • ICH-compliant stability testing Perform ICH-compliant stability testing
  • Regulatory Starting Materials Sourcing regulatory starting materials (RSM)

Discovery Chemistry

  • Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
  • Custom Libraries Find or synthesize mg to kg amounts of target-specific and target-agnostic compounds for HTS and biological profiling.
  • Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
  • Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
Show all 9 in Discovery Chemistry 3 more
  • Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
  • Trace Elemental Analysis Identify organic and inorganic elements in foods and dietary supplements at ppm to sub-ppt levels.
  • UV and IR Profiling Analyze the integrity of a compound or large biomolecule.
Show all 24 services 7 more

Nanotechnology

  • Nanoparticle Synthesis Create nano-level structures with unique features.

Testing Services

  • Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.

Service areas:

Chemistry

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Durham, Sedgefield 3 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

High Force Research provides chemical synthesis and R&D for chemical development.

Professional associations
RSC
Website
www.hfrchemistry.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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