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Research supplier
Propath UK Limited
Propath UK Limited is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Antibodies
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
Biomarkers
- Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Show all 15 in Biomarkers
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
- Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
- Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
- TUNEL Assay Detect in situ DNA fragmentation.
Cell Culture and Characterization
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.
Data Science/Bioinformatics
- Clinical Data Analysis Analysis that helps you make sense of your clinical data
- Discovery Data Analysis Analysis that helps you make sense of your discovery data
- Discovery Omics Analytics A process to analyze various omics data (genomics, transcriptomics, proteomics, metabolomics, etc.) This can include the integration of different omics data. Helps to better understand the molecular environment...
- Translational Bioinformatics Different analytical approaches that make, store, and analyze complex biological data.
- Translational Data Analysis Analysis that helps you make sense of your translational data
- Translational Data Harmonization and Integration Process to combine different data together for better understanding and analysis of the integrated data.
Show all 8 in Data Science/Bioinformatics
- Translational Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
- Translational Omics Analytics A process to analyze various omics data (genomics, transcriptomics, proteomics, metabolomics, etc.) This can include the integration of different omics data. Helps to better understand the molecular environment...
Show all 46 services
DNA & RNA
- DNA Extraction Extract DNA from an original source.
- Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
- miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
Show all 10 in DNA & RNA
- RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
- RNAscope In Situ Assays Profile single-cell gene expression in situ.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
- Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
Oncology Models
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Protein Sciences
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Safety Pharmacology
- Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- NGS: Next Generation Sequencing Data Analysis Use software to interpret data created by RNA-Seq, DNA-Seq, ChIP-Seq and DNA methylation experiments.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
United Kingdom 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Propath is a leader in Europe for histopathology and molecular pathology. As an accredited GLP facility, our experience of regulatory and research studies spans over 30 years. We provide expert, regulatory compliant services in histology, immunohistochemistry, in situ hybridisation, tissue cross-reactivity, pathology evaluation and whole slide digital scanning. Our focus is on preclinical safety assessment of pharmaceuticals, therapeutic antibodies, chemicals and medical devices; and our strengths are in supporting regulatory toxicology studies and assessing on/off‐target binding...
Show the full description
Propath is a leader in Europe for histopathology and molecular pathology. As an accredited GLP facility, our experience of regulatory and research studies spans over 30 years.
We provide expert, regulatory compliant services in histology, immunohistochemistry, in situ hybridisation, tissue cross-reactivity, pathology evaluation and whole slide digital scanning.
Our focus is on preclinical safety assessment of pharmaceuticals, therapeutic antibodies, chemicals and medical devices; and our strengths are in supporting regulatory toxicology studies and assessing on/off‐target binding and biodistribution of novel therapeutic antibodies.
We serve clients across the pharmaceutical and biopharmaceutical spectrum, chemical and agrochemical companies, contract research organisations, research institutes and government departments.
Our reputation has been gained by focusing relentlessly on the quality of our advice, the standard of our work and the responsiveness of our service.
- Website
- www.propath.co.uk
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