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MedChem Express
MedChem Express is listed as a small business research supplier in the Scientist.com network, with 4 sites in 2 countries.
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Sites
4
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Agricultural Sciences Research & Development
- Vaccines Testing transgenic plants as promising systems for vaccine production.
Antibodies
- Affinity Maturation Use mutagenesis to optimize a complementary determining region and increase antibody affinity.
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
- Antibody Discovery Identifying and developing antibodies that specifically bind to target antigens for therapeutic or diagnostic use.
- Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
- Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
Show all 22 in Antibodies
- Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
- Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
- Custom Antibodies Design and produce polyclonal and monoclonal antibodies.
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
- Hybridoma Sequencing/Antibody Sequencing Determine the sequences of monoclonal antibodies.
- Immunodetection Use antibodies to identify a protein or antigen.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
- Monoclonal/Polyclonal Antibody Development Develop a monoclonal and/or polyclonal antibody.
- Phosphospecific Antibodies Create antibodies to detect phosphorylated protein targets.
- Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
- Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
- Rabbit Monoclonal Antibody Development Develop monoclonal antibodies using rabbit as the host animal.
- Recombinant Antibody Production Request services related to antibody production services.
- SARS-CoV-2 (COVID-19) Antibodies Search for available SARS-COV-2 antibodies
Bioimaging
- In Vivo Imaging In-vivo imaging using PET, MRI, CT etc.
- In-vivo Fluorescence In-vivo fluorescence enables visualisation and the study of biological processes in live organisms by using fluorescent markers.
- Luminescence Imaging Monitor biological processes and pathologies using reporter proteins such as firefly and Renilla luciferase.
Biomarkers
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
- Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
- Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
Show all 136 services
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
- Induced Pluripotent Stem (iPS) Cell Reprogramming Generate induced pluripotent stem cells from adult somatic cells.
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
- Stem Cell Methodologies Study Stem Cell characteristics.
Chemical and Compound Analysis
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Compound Integrity Analyze the identity and purity of small molecule drug candidates.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
- Impurities in API Risk assessment Create a risk-based control strategy to determine any impurities in Active Pharmaceutical Ingredients (API).
- Ion Exchange Chromatography Separate and detect analytes.
Show all 11 in Chemical and Compound Analysis
- Natural Product Libraries Find microbial, botanical and marine sources of natural products.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
- Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.
Chemistry, Manufacturing and Controls (CMC)
- API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
- Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
Clinical Consulting
- Antibody Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Data Science/Bioinformatics
- Discovery Machine Learning/AI Complex analytical approaches to find patterns and make predictions in drug discovery projects.
Discovery Chemistry
- Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
- Certified Standards Find certified standards for assays, tests and services.
- Compound Purchase Buy compounds, building blocks or compound libraries.
- Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
Show all 14 in Discovery Chemistry
- DNA Encoded Library (DEL) capabilities The rapid screening of vast chemical libraries by encoding millions of small molecules with unique DNA sequences, facilitating the identification of potential drug candidates.
- Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
- HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
- Natural Product Screening Screen large natural product collections for therapeutic activity.
- Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
- Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
- Target-Focused Compound Libraries Find activity-based libraries directed towards a protein or cell signaling target.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Disease Models
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
DNA & RNA
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- DNA Library Screening Screen genomic or cDNA libraries for positive clones.
- DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
- mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
- Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
- Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
Show all 8 in DNA & RNA
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
Farm & Livestock Solutions
- Serology/Immunology Testing for BSE/TSE
General in vivo Toxicology
- Avian Toxicology Investigation Use toxicity tests to predict avian exposure risk, assess exposure effects or confirm product safety for registration.
- Short-Term Toxicity Tests Acquire preliminary data about the concentrations, exposure duration and effects of a toxin on organisms.
Human Biological Samples
- Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
- Human Organoids Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy...
In Vitro ADME
- Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
- Reference Standards Find reference standards for assays, tests and services.
In Vitro Assays
- Antivirals Measure anti-viral activity in biochemical and cell assays.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- Glycobiology Study the structure biosynthesis and biology of carbohydrates
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
Show all 8 in In Vitro Assays
- Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
In Vitro Pharmacology
- G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
- Nucleoside Transporter Assays Use biochemical, cell-based or in vivo assays to measure nucleoside transporter activity.
- Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
- Protease Assay Measure protease activity in biochemical and cell-based assays.
Show all 8 in In Vitro Pharmacology
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
- Protein/Enzyme Targets For requesting Protein/Enzyme Targets
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
Nanotechnology
- Drug Delivery Technology Create microstructures that enhance drug metabolism properties.
- Liposomes Create artificial spherical vesicles that can be used as a vehicle for administration of drugs.
- Nanobodies Use heavy-chain only antibodies to create antigen-specific single variable domain fragments.
- Nanoparticle Synthesis Create nano-level structures with unique features.
Other Specialty Toxicology
- Static Acute Toxicity Test Measure toxicity endpoints in aquatic organisms exposed to a non-renewed test solution for the entire experiment.
Product Orders
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
- Lab Supplies Fill out the details below to request a quote:
Protein Sciences
- Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Show all 19 in Protein Sciences
- Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
- Lentivirus Production Develop lentiviruses and production protocols.
- Peptide Derivatives Acquire chemicals that are peptide derivatives.
- Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
- Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
- Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
- Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
- Virus Production Produce high titer viruses, viral expression vectors and vaccines.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
- X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
REACH Services
- OECD 417: Toxicokinetics Study Obtain data on absorption, distribution, metabolism, and elimination of test substances.
- OECD 429: Skin Sensitisation (Local Lymph Node Assay) Assess the skin sensitization potential of chemicals.
- OECD 452: Chronic Toxicity Studies Evaluate the direct and indirect impact of prolonged and repeated toxin exposure to test organisms.
Scientific Data Services
- Molecular Dynamics Software Run simulations that determine time-dependent behaviors of molecular systems.
Other services
- New Request
- Website
- www.medchemexpress.com
Where it operates
Sites by country, with the cities in each.
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Sweden 2 sites
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United States 2 sites
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