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Medinoah
Medinoah is listed as a small business research supplier in the Scientist.com network, with 3 sites in 2 countries and 1 service area.
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Sites
3
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Chemical and Compound Analysis
- Analytical Separations and Purification Analytical Separation and Purification of compound/molecule.
- API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
- Chemical Stability Measure the stability of small molecules in solution.
- Chiral Separation Purify therapeutically active isomers of drug candidates.
- Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Show all 23 in Chemical and Compound Analysis
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
- Heavy Metals Analysis Ensure trace levels of heavy metals are below the maximum allowable limits for consumer safety.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) Analysis Detect metals and several non-metals at concentrations as low as one part in 1015 (part per quadrillion, ppq) on non-interfered low-background isotopes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
- NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
- NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
- Optical Rotation Distinguish between optical isomers as well as between natural versus man-made compounds.
- Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Phototoxicity & Photosensitization Test Test the potential for a product to elicit a reaction under UV exposure.
- Physicochemical Analysis Physicochemical Analysis of material or preparation evaluating (e.g.) particle size, composition, or compound structure.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Chemical and Compound Testing
- USP <2021> Microbial Enumeration Tests Estimate the total aerobic microbial count, total combined yeast and mold counts, and the presence of bile-tolerant gram-negative bacteria present in nutritional supplements.
- USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.
- USP <85> Bacterial Endotoxin Test Test to detect or quantify bacterial endotoxins that may be present in or on a sample.
Chemistry, Manufacturing and Controls (CMC)
- Advanced intermediates Sourcing advanced intermediates
- Analytical Development and Validation Request services related to Analytical Development and Validation
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
Show all 23 in Chemistry, Manufacturing and Controls (CMC)
- API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
- Bulk Manufacturing Find facilities for large-scale mass production.
- Bulk Raw Materials Acquire raw materials in large volumes at wholesale pricing.
- Crystallization studies Crystallization studies
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
- ICH-compliant stability testing Perform ICH-compliant stability testing
- Milling, grinding, spray-drying Milling, grinding, spray-drying
- Polymorph Screening Screen for unwanted API forms resulting from the drug formulation process.
- Powder Filling Use manual, automatic or semi-automatic machinery to package a variety of powder and granules.
- Raw Materials & Ingredients Purchase raw materials, ingredients, or chemicals for personal care, cosmetic, consumer health, and beauty products and substances.
- Regulatory Starting Materials Sourcing regulatory starting materials (RSM)
- Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
- Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
- Thermo Scientific iCAP Q ICP-MS Expand your analytical capabilities with this complete trace elemental analysis solution for your high-throughput lab.
Show all 72 services
Discovery Chemistry
- Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
- Compound Purchase Buy compounds, building blocks or compound libraries.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
- Custom Libraries Find or synthesize mg to kg amounts of target-specific and target-agnostic compounds for HTS and biological profiling.
- Custom Synthesis Find or synthesize mg to kg amounts of target-specific and target agnostic compounds for HTS and biological screening.
Show all 16 in Discovery Chemistry
- Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- Pharmaceutical Research Chemicals Acquire chemicals that are prospective new drug entities.
- Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
- Structure Property Relationship (SPR) Determine the functionality of a compound through the analysis of it's structure.
- Trace Elemental Analysis Identify organic and inorganic elements in foods and dietary supplements at ppm to sub-ppt levels.
Drug Development
- Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
- Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.
Food Safety & Regulations
- Water Activity Determine water activity in consumer healthcare products involving a USP or FCC monograph.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- Microbiological Sterility Testing Test the presence of viable microorganisms.
- Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
Service areas:
Chemistry
Where it operates
Sites by country, with the cities in each.
-
China 2 sites
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Medinoah provides chemistry services, including library synthesis, lead optiization, medicianl chemistry and process development.
- Professional associations
- ACS
- Website
- medinoah.com
Work with Medinoah on Scientist.com
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