2bind GmbH

2bind GmbH is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1

Countries 1

Type of company: Small business

Antibodies

Affinity Maturation Use mutagenesis to optimize a complementary determining region and increase antibody affinity.
Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.

Chemical and Compound Analysis

Chemical Stability Measure the stability of small molecules in solution.
Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
Protein Melting Point Analysis Assess protein stability by Differential Scanning Calorimetry (DSC) or Fluorimetry (Thermofluor) methods.

Chemistry, Manufacturing and Controls (CMC)

Analytical Development and Validation Request services related to Analytical Development and Validation
Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
Biotherapeutics Discover smarter treatments based on cells and biological molecules.
Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Formulation Development Optimize bioavailability, stability, salt forms, plasma stability and excipient release in vivo.
Fragment Screening Screen fragment libraries for activity against a protein or cellular target.

Show all 7 in Chemistry, Manufacturing and Controls (CMC) 1 more

Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.

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Data Science/Bioinformatics

In Silico Epigenetic Compound Library Screening Use computer-aided methods to discover new compounds against key regulators of epigenetic signaling.

Discovery Chemistry

Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.

In Vitro ADME

Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
Protein Aggregation Determine the aggregation state of antibody and protein-based therapeutics.

In Vitro Assays

Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
HTS Assay Development Develop assays to use in high throughput screening.

In Vitro Pharmacology

High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.

Nanotechnology

Nanobodies Use heavy-chain only antibodies to create antigen-specific single variable domain fragments.

Protein Sciences

Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
Protein Analysis Analyze the structure, activity, interactions and distribution of proteins.
Protein Binding Determine drug-protein binding interactions
Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.

Other services

nanoDSF Service Analyze the conformational and colloidal stability of proteins.

Website: 2bind.com

Germany Regensburg 1 site

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