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3D BioOptima

3D BioOptima is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Chemical and Compound Analysis

  • Chemical Stability Measure the stability of small molecules in solution.
  • Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
  • Sample Bioanalysis Determination of concentration of an analyte in biological sample.

Disease Models

  • Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
  • Microdialysis Models Measure the effect of drug candidates on neurotransmission in rat or mouse models.

In Vitro ADME

  • Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
  • HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
  • Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
  • Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.

Protein Sciences

  • Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
  • Protein Binding Determine drug-protein binding interactions

Other services

  • New Request  

Service areas:

DMPK

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • China Suzhou, 苏州市 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

3D BioOptima offers the following specialized DMPK services complying with national and international standards. Bioanalytical Chemistry Method development/validation/transfer Single compound and/or metabolite(s) Multiple compounds and/or metabolites In vitro sample analysis In vivo animal sample analysis Clinical sample analysis In Vitro ADME Metabolic stability/species comparison Reaction phenotyping Enzyme inhibition/induction Metabolite profiling and identification Caco-2 permeability Plasma protein binding In Vivo ADME Blood-to-plasma ratio Blood-brain barrier penetration Microdialysis...

Show the full description

3D BioOptima offers the following specialized DMPK services complying with national and international standards.

Bioanalytical Chemistry

Method development/validation/transfer
Single compound and/or metabolite(s)
Multiple compounds and/or metabolites
In vitro sample analysis
In vivo animal sample analysis
Clinical sample analysis

In Vitro ADME

Metabolic stability/species comparison
Reaction phenotyping
Enzyme inhibition/induction
Metabolite profiling and identification
Caco-2 permeability
Plasma protein binding

In Vivo ADME

Blood-to-plasma ratio
Blood-brain barrier penetration
Microdialysis and CSF sampling
Single-pass intestinal perfusion
Mesenteric blood sampling
Portal-vein infusion
Biliary/urinary/fecal excretion
Tissue distribution
Metabolite profiling and identification

High-Throughput ADME

Rat liver microsomal stability
Human liver microsomal stability
Human liver microsomal P450 inhibition
PAMPA permeability
Log D
Solubility

ADME-Assisted Lead Optimization

Quick in vitro metabolism screening
Quick animal PK screening
“Soft” spot identification
“Hot” spot identification
“Soft” spot structural modification
“Hot” spot structural modification

PK, PK/PD, and TK

Chemical/biological therapeutics
Single/multiple/cassette dosing
Bioavailability and bioequivalence
Dose proportionality
Drug-drug interaction
PK/PD relationship analysis
Human dose projection
Dried blood spot sampling
TK

Website
www.3dbiooptima.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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