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Noble Life Sciences
Noble Life Sciences is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 4 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
- Medical Imaging Visualize and analyze internal structures in animal models or patients.
Biomarkers
- Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Show all 9 in Biomarkers
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Cell Culture and Characterization
- Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
Chemical and Compound Testing
- Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
- Product Testing Ensure product quality standards are met.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Show all 59 services
Developmental and Reproductive Toxicology (DART)
- Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.
Disease Models
- Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
- Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Cartilage Repair Models Measure therapeutic endpoints in animal models of cartilage repair.
- Hematopoiesis Models Measure therapeutic endpoints in animal models of hematopoiesis.
- Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
Show all 13 in Disease Models
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
- Spinal Cord Injury Models Measure therapeutic endpoints in models of spinal cord injury.
- Thrombosis Models Measure therapeutic endpoints in animal models of thrombosis.
- Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.
- Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.
DNA & RNA
- DNA Isolation Isolate or extract high-quality DNA.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
- Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.
In Vitro Assays
- Antivirals Measure anti-viral activity in biochemical and cell assays.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- Microbiology Study microbes and their role in human health.
In Vitro Pharmacology
- In Vitro Hemolysis Assay Evaluate the toxicity of a drug, metabolite or excipient by hemolytic release of hemoglobin in the plasma.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
- Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
Show all 9 in In Vivo Pharmacokinetics
- Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
- Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
- Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- Juvenile Toxicology Assess developmental and reproductive defects due to neurobehavioral, skeletal and muscle growth effects.
- Standard Models Create new animal disease models or modify existing models to study specific diseases, side-effects or symptoms.
- Surgical Models Create new animal models using techniques such as vascular catherization, soft tissue procedures or device implants.
Oncology Models
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Other Specialty Toxicology
- Tumorigenicity Testing Test tumor-forming properties of cell products.
Specialty Dosing Routes
- Dermal Toxicology Assess toxicity in rodent dermal testing models.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Noble Life Sciences offers vivarium and preclinical drug development services including biomarker discovery, in vivo PK studies, xenografts, efficacy modeling, dose range finding, and gene expression assays in a variety of research animals. Noble Life Sciences was founded by five veteran biotech industry leaders to meet the R&D needs of clients in the biotech and pharmaceutical industries as well as academia. As scientists and former CRO customers, our goal from the very beginning was to improve the outsourcing experience for our clients by delivering the highest quality data, on-time...
Show the full description
Noble Life Sciences offers vivarium and preclinical drug development services including biomarker discovery, in vivo PK studies, xenografts, efficacy modeling, dose range finding, and gene expression assays in a variety of research animals.
Noble Life Sciences was founded by five veteran biotech industry leaders to meet the R&D needs of clients in the biotech and pharmaceutical industries as well as academia. As scientists and former CRO customers, our goal from the very beginning was to improve the outsourcing experience for our clients by delivering the highest quality data, on-time.
Leveraging our specialized expertise in personalized medicine and biomarker research and preclinical drug development, we offer a depth and breadth of services under one roof while maintaining a steadfast commitment to quality in every area of operations.
Our centralized location in Montgomery County makes Noble easily accessible to clients in the Baltimore-Washington area and throughout the mid-Atlantic.
- Website
- www.noblelifesci.com
Supplier diversity
SAM.gov small-business designations
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
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