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BioIVT

BioIVT is listed as a mid sized business research supplier in the Scientist.com network, with 11 sites in 4 countries and 1 service area.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 11

Countries 4

Type of company: Mid sized business

Antibodies

AlphaLISA Quantification of analytes with high sensitivity, wider dynamic range and no wash steps involved.
Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Immunodetection Use antibodies to identify a protein or antigen.

Bioimaging

Bioimaging Visualize biological process non-invasively in real time.
Microscopy Use microscopy to analyze surfaces of biological materials and to develop 3D images of biological structures.

Biomarkers

Adipogenesis Assay Detect and quantify intracellular triglyceride accumulation in adipocytes.
Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.

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Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
HCS Assay Development Requesting services related to HCS assay development.
Hematology CBC Run automated and manual complete blood cell counts (CBCs) as well as microscopic evaluations of cell types.
Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
Histamine Release Assay Use in vivo or in vitro assays to measure the release of histamine in response to an allergen stimulation.
Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Human Primary Cell Isolation Isolate primary cells from various human tissues.
Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
Lipid Peroxidation Assay Use in vitro or in vivo assays to evaluate the effects of oxidative stress on lipid structure and function.
Multiplex Circulating miRNA Assay Profile miRNAs directly from just 10 μl of crude biofluid or 0.1 ng of purified RNA.
Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Solid Tumor CDx Design and validate companion diagnostics for solid tumors that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
TUNEL Assay Detect in situ DNA fragmentation.
Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.

Cell Culture and Characterization

3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
Cell Culture Culture primary or immortalized cell lines.
Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
Cell Sorting The purpose of cell separation is to isolate a cell population from other cells in a biological sample.

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Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
Chromosomal Characterization Establish karyotype/chromosome profile by cytogenetic analysis of cell preparation.
Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
Custom 3D Microtissue Development Convert cell lines into highly functional 3D microtissues using scaffold-free self-assembly.
Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
H & E Services For requesting services related to H&E Services
Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Human Melanoma Cell Lines Obtain highly characterized cell lines derived from patients’ tumors for in vitro and in vivo modelling.
Karyotyping Evaluate the number and appearance of chromosomes in the nucleus of a eukaryotic cell.
Lipofection Transfection of DNA/RNA using lipofection reagents to create lipoplexes.
Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
Resin-based Histology Perform sectioning and histological analysis of epoxy/acrylic/polycarbonate-embedded samples.
RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Spent Media Analysis Measure chemical alterations, such as variations in amino acids, glucose, contaminants, and metabolites, in a cell culture medium throughout the culturing process.
Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Stem Cell Methodologies Study Stem Cell characteristics.
Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.
Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

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Chemical and Compound Analysis

Bioanalysis Bioanalysis involves the determination of the concentration of test compounds in biological samples including plasma, urine, an...
Compound Integrity Analyze the identity and purity of small molecule drug candidates.
Compound Purification Purify compounds using preparative HPLC, exchange resins, filtration and crystallization.
Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.

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GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Liquid Chromatography Separate substances using a mobile and stationary phase.
NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Photostability Measure drug degradation rates after exposure to various light sources.
Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Secondary Ion Mass Spectrometry Detect trace level impurities and obtain elemental or molecular chemical data for solid sample surfaces.
Structural Chemistry Examine the relationship between protein structure and function.
Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.

Chemical and Compound Testing

Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.

Chemistry, Manufacturing and Controls (CMC)

Chemistry Manufacturing Controls Access contract manufacturing and regulatory guidance in setting specifications and drug dosage formulations.
Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
Formulation Development Optimize bioavailability, stability, salt forms, plasma stability and excipient release in vivo.
Plant Extracts Acquire plant extracts, such as lutein, lycopene, and quinine, to use as ingredients in consumer healthcare products.

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Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
Subcellular Fraction Test System Obtain human, minipig, mouse, or rat dermal microsomes as in-stock standard test systems for the development of safer topical and transdermal products.

Clinical Consulting

Bioanalysis Consulting Expert advice to properly and effectively discover, evaluate, and measure chemical or biological materials.
Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
IND Writing Consulting Consulting for an Investigational New Drug Application
Product Testing Consulting Expert advice to evaluate the effectiveness, quality, and legitimacy of a given item or good.
Regulatory Consulting Ensure that each product or device complies with all FDA rules and regulations.

Clinical Trials

Clinical Research Services Determine the safety and effectiveness of medications and medical devices.

Companion Diagnostics

Cervical Cancer CDx Design and validate companion diagnostics for cervical cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Pancreatic Cancer CDx Design and validate companion diagnostics for pancreatic cancer that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.
Rheumatoid Arthritis (RA) CDx Design and validate companion diagnostics for RA that help select the most appropriate patients, identify patients at increased risk, or monitor treatment effectiveness.

Discovery Chemistry

Compound Purchase Buy compounds, building blocks or compound libraries.
Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Radiochemical Synthesis Radiolabel small molecules, peptides, cytotoxics or antibody drug conjugates for DMPK analysis.
Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...

Disease Models

Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
Auto-immune Hepatitis Models Measure therapeutic endpoints in animal models with auto-immune hepatitis.
Autoimmune Models Measure therapeutic endpoints in animal models with autoimmune disorders.
Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
Cataract Models Measure therapeutic endpoints in animal models of cataracts.

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Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
db db Diabetic Mice Test for therapeutic efficacy of drug candidates in diabetic mouse models.
Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
Diabetic Retinopathy Models Assess therapeutic efficacy of drug candidates in diabetic retinopathy models of disease.
Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
Dry Eye Models Measure therapeutic endpoints such as tear induction, TBUT, Schirmer strips (tear volume) and cornea staining.
General Pain Models Measure therapeutic endpoints in animal models of general pain.
Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
Huntington's Disease Models Measure therapeutic endpoints in animal models of Huntington's disease.
IGA Glomerulonephritis Models Measure therapeutic endpoints in animal models of IgA glomerulonephritis.
Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
Kidney Transplant Models Measure therapeutic endpoints in kidney transplant models.
LCMV Mouse Use a single animal species to create disease models for virus-induced immunity and immunopathology.
Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
LPS Acute Response Models Measure therapeutic endpoints in acute models of inflammation.
Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
Malaria Models Measure therapeutic endpoints in animal models of malaria.
Myelination Models Measure therapeutic endpoints in animal models with induced myelination, remyelination or developmental myelination.
Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
Obese Primates Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
Ocular Inflammation Models Measure ocular inflammation in models of eye disorders such as uveitis and keratitis.
Ophthalmic Models Test drug candidates in glaucoma, macular degeneration, keratitis, uveitis and CMV retinitis models.
Osteoarthritic Pain Models Measure therapeutic endpoints in animal models of osteoarthritic pain.
Pain Endpoints Models Measure therapeutic endpoints in animal models of pain.
Pain Model Consulting Expert advice to better evaluate and understand pain thresholds and phenomena within living organisms. Can be used to evaluate pain associated with specific diseases or injuries affecting the sensory and nervous systems.
Pain Models Test therapeutic efficacy of drug candidate in pain model.
Parkinson's Disease Models Measure therapeutic endpoints in animal models of Parkinson's disease.
Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
SHR/NCrl Rat Use a single animal species to create one or more disease models fior hematopoesis.
Skin Graft Models Measure therapeutic endpoints in animal models of skin grafts.
Streptozotocin Rats Use a single animal species to create one or more disease models for Type 1 diabetes.
Systemic Lupus Erythematosus Models Measure therapeutic endpoints in animal models of immune disorders such as SLE and lupus.
Thrombosis Models Measure therapeutic endpoints in animal models of thrombosis.
Visceral Pain Models Measure therapeutic endpoints in animal models of visceral pain.
Weanling Rat Use a single animal species to create one or more disease models for anemia.

DNA & RNA

Amplicon - HLA Typing Use an amplicon sequencing method to identify allelic variation within the HLA genes.
ddPCR-Based Plasma Genotyping Perform noninvasive tumor genotyping.
DNA Extraction Extract DNA from an original source.
DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
DNA Sequencing Determine the nucleotide sequence of DNA samples.
DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.

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Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
Genotyping Examine a DNA sequence to identify specific genetic varients .
In Situ Hybridization Localize specific nucleic acid targets using labeled complementary probes.
miRNA sequencing Identify miRNAs by Next Generation Sequencing and bioinformatic analysis.
NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
qPCR Analysis Measure the accumulation of PCR products in real time.
Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
RNA Extraction Isolate total RNA or mRNA from cells or tissues
RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
RNAscope In Situ Assays Profile single-cell gene expression in situ.
Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.
Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.

Drug Development

Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Consulting Services Work with consultants who provide expert advice in various areas of research and technology.
Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.
Small Molecule Drug Development Consulting Request consulting services related to small molecule development.
Structural Chemistry Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.

Food Safety & Regulations

Salmonella spp. Testing Use molecular, immunological or cultured methods to identify the presence of Salmonella species in food or contact-surface samples.

General in vivo Toxicology

General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

Human Biological Samples

Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
BronchoAlveolar Lavage (BAL) Acquire fresh/frozen normal bronchial lavage based on patient demographics and history.
Cell Line and Cellular Services Promotion for Cells and Cell lines
FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
HBS Alzheimer's Acquire fresh, frozen, or fixed Alzheimer's tissues or other related Alzheimer's HBS.
HBS Amyotrophic Lateral Sclerosis (ALS) For requesting HBS Amyotrophic Lateral Sclerosis (ALS).

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HBS Asthma For requesting HBS Asthma.
HBS Autoimmune Diseases For requesting Autoimmune Diseases HBS.
HBS Bacterial Infections Provision of HBS Bacterial Infections samples
HBS Chronic Obstructive Pulmonary Disease (COPD) Acquire fresh, frozen, or fixed COPD tissue or for requesting other COPD human biospecimen samples.
HBS Diabetes For requesting HBS Diabetes.
HBS Fungal Infections Provision of HBS Fungal Infections samples
HBS Genetic Diseases For requesting Genetic Diseases HBS
HBS Healthy/Controls For requesting HBS Healthy/Controls
HBS HepB positive For requesting HBS HepB positive.
HBS HepC positive For requesting HBS HepC positive
HBS HIV positive For requesting HBS HIV positive
HBS Huntington's For requesting HBS Huntington's.
HBS Leukemia For requesting HBS Leukemia
HBS Liver Disease Request samples from patients with Liver Disease.
HBS NASH For requesting HBS NASH
HBS Neurological Diseases For requesting Neurological Diseases HBS
HBS Oncology For requesting Human biospecimens from Oncology indications
HBS Parkinson's For requesting HBS Parkinson's
HBS Viral Infections For requesting Viral Infection HBS
HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
HBS: Human Biological Samples - VMS Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
Human Amniotic Fluid Acquire fresh/frozen normal amniotic fluid based on patient demographics and history.
Human Ascites Acquire fresh/frozen Ascites based on patient demographics, disease stage, treatment and history.
Human Biofluids Acquire fresh/frozen biofluids based on patient demographics, disease stage, history and treatment.
Human Blood Acquire fresh/frozen human blood based on patient demographics, disease stage, history and treatment.
Human Blood by-products For requesting Human Blood By-products
Human Bone Marrow Aspirates Acquire fresh/frozen Bone Marrow mononuclear cells based on patient demographics, disease stage, treatment and history.
Human Bone Marrow Cells Acquire fresh, frozen, or fixed normal bone marrow based on patient demographics and history.
Human Breast Milk Acquire fresh/frozen normal breast milk based on patient demographics and history.
Human Buffy Coats Acquire fresh/frozen Buffy Coats based on patient demographics, disease stage, treatment and history.
Human Cell Lysates For requesting human Cell lysates.
Human Cell Products For requesting human cell by products like proteins, lysates, lysosomes etc
Human Cerebral Spinal Fluid (CSF) Acquire fresh/frozen normal cerebrospinal fluid based on patient demographics and history.
Human DNA Acquire human DNA.
Human DNA & RNA Acquire fresh/frozen Human DNA & RNA based on patient demographics, disease stage, treatment and history
Human Exosomes Request services related to the creation and development of human exosomes
Human Fecal Matter Acquire fresh/frozen normal feces based on patient demographics and history.
Human Fixed Tissue Acquire Human fixed tissue based on patient demographics, disease stage, history and treatment.
Human Fresh Tissue For requesting fresh human tissue
Human Frozen Tissue For requesting frozen human tissue.
Human Hepatocytes Acquire human hepatocytes isolated from the liver.
Human HSC's For requesting human sourced hematopoetic stem cells
Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
Human Leukopaks Obtain enriched leukapheresis-derived products from normal peripheral blood.
Human Mammary Epithelial Cells Acquire human epithelial cells isolated from the mammary gland.
Human MSC's For requesting human sourced mesenchymal stem cells.
Human Nasal Fluid Acquire fresh/frozen normal nasal fluid based on patient demographics and history.
Human Neural Stem Cells Acquire human neural stem cells isolated from brain tissue.
Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
Human Plasma Acquire fresh/frozen human plasma
Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
Human Pulmonary Artery Endothelial Cells Acquire human endothelial cells isolated from the pulmonary artery.
Human Red Blood Cells Acquire fresh/frozen normal red blood cells based on patient demographics and history.
Human RNA Acquire fresh/frozen Human RNA based on patient demographics, disease stage, treatment and history.
Human Saliva Acquire fresh/frozen normal saliva based on patient demographics and history.
Human Semen Acquire fresh/frozen normal semen based on patient demographics and history.
Human Serum Acquire fresh/frozen normal serum based on patient demographics and history.
Human Sputum Acquire fresh/frozen normal sputum based on patient demographics and history.
Human Synovial Fluid Acquire fresh/frozen normal synovial fluid based on patient demographics and history.
Human Tears Acquire fresh/frozen Tears based on patient demographics, disease stage, treatment and history.
Human TMA For requesting Human Tissue MicroArrays
Human Umbilical Cord Blood For requesting Human Umbilical Cord Blood.
Human Urine Acquire fresh/frozen normal urine based on patient demographics and history.
Human Vaginal Fluid/ Swab Acquire fresh/frozen normal vaginal fluid based on patient demographics and history.
Human Vitreous Humor Acquire fresh/frozen normal vitreous humor based on patient demographics and history.
Human Whole Blood Acquire fresh/frozen normal whole blood based on patient demographics and history.
Human Whole Blood For requesting Human Whole Blood
Human Whole Organs Procure non-transplantable whole human organs or tissues, healthy or diseased, for medical research and development.
SARS-CoV-2 (COVID-19) Human Biological Samples Search for available SARS-CoV-2 human biological samples
Tissue Acquisition Find primary animal and human tissues and cells.

In Vitro ADME

Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
Cell Fractionation Isolate organelles and subcellular components.
Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.

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CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
GI Fluid Stability Determine dosing and turnover of drug candidates in gastrointestinal fluids.
HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
In Vitro ADME in Vitro ADME services
In Vitro Biologic-Small Molecule Drug-Drug Interaction Studies Patented approach to evaluate the potential of large &/or small molecule drugs to cause DDI directly or through cytokine effect.
Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.
Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
Multidrug Resistance Identify potential causes of drug-drug interactions.
N Acetyl Transferase Detect NAT induction and identify any acetylated-drug conjugates that are formed.
No Label Methods Use mass spectrometry to detect and identify non-radiolabeled drug intermediates in pre-clinical samples.
Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
Radiolabeled Tracers Use radiolabeled drug metabolites as radiotracers for measuring desired physiological processes.
Reactive Metabolite Ensure that your drug candidate is not generating toxic reactive metabolites in vivo.
Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
Sulfotransferase Detect sulfotransferase (SULT) induction and the formation of sulfonated-drug conjugates.

In Vitro Assays

Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Apoptotic Cell Staining Detect apoptotic cells in culture.
Assay Development Construct or create new assays or modify existing ones.
Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.

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Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Cell Proliferation Measure cell number, cell viability and cell division.
Cell-based Assay Development Develop new cell based assays or modify existing ones.
Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
Fully Automated Assays Develop and perform assays that require no manual steps
Glucose Release Assay Determine free glucose levels in biological samples.
Glucose Uptake Measure glucose uptake in cultured cells using GLUT4 signaling assays.
High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
HTS Assay Development Develop assays to use in high throughput screening.
Human Custom TMA For requesting Human Custom Microarray Services
In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Human Cell Assays Request in vitro human cells for assays
In Vitro SPF (Sun Protection Factor) Testing Use in vitro test methods to measure the UVA protection performance of sun protection products.
Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.
Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
Lipolysis Measure the hydrolysis of triglycerides into glycerol and free fatty acids.
Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
Microbiology Study microbes and their role in human health.
Monoamine Transporter Assays Measure monoamine neurotransmitter uptake in cultured cells.
MTT Test Measure the viability of living cells via mitochondrial dehydrogenase activity.
Oxidative Burst Examine the release of reactive oxygen species (ROS) from neutrophils and other immune cells.
Pathology Services Pathology Services
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
Serine Protease Assay Detect apoptosis by measuring protease activity.
Tube Formation Assay Monitor the in vitro formation of three dimensional 3D tube structures.

In Vitro Pharmacology

Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
Extracellular signal Regulated Kinase Assays Use biochemical, cell based or in vivo assays to measure ERK enzyme activity.
Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.
High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.

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In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
In Vitro Hepatotoxicity Assays Use in vitro assays to measure hepatoxicity-related activities.
Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Mitogen/Extracellular signal-regulated Kinase (MEK) Assays Use biochemical, cell based or in vivo assays to measure MEK enzyme activity.
Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
Nucleoside Transporter Assays Use biochemical, cell-based or in vivo assays to measure nucleoside transporter activity.
Peptide Transporter Assays Use biochemical, cell-based or in vivo assays to measure peptide transporter activity.
Programmed Cell Death-1 (PD-1) Assays Use biochemical, cell based or in vivo assays to measure PD-1 receptor activity.
Protein Kinase B (Akt) Assays Use biochemical, cell based or in vivo assays to measure Akt enzyme activity.
Reversibility Study Determine whether or not a compound inhibits an enzyme reversibly.
Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
Solute-Linked Carrier (SLC) Transporter Inhibition Assays Use biochemical, cell-based or in vivo assays to measure solute-linked carrier transporter activity.
Solute-Linked Carrier (SLC) Transporter Substrate Identification Use biochemical, cell-based or in vivo assays to identify solute-linked carrier transporter substrates.
Substrate Competitive Study Determine whether or not a compound is competitive with a substrate.
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
Transporter Assays Use biochemical, cell-based or in vitro assays to measure transporter target activity.
UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.
Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation
Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
HepaRG Cells Obtain terminally differentiated and cryopreserved hepatic cells that retain many characteristics of primary human hepatocytes.

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Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
Tubule Epithelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the kidney.

In Vivo ADME

Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
Chronic Bile Duct Cannulation (BDC) Study - Other Species Conduct a bile duct cannulation (BDC) study in other species to support the absorption, distribution, metabolism and excretion profiling of your compound.
Chronic Bile Duct Cannulation (BDC) Study - Rat Conduct a bile duct cannulation (BDC) study in rats to support the absorption, distribution, metabolism and excretion profiling of your compound.
Expired Air Study - Mouse Conduct a study to collect expired air and monitor its radioactivity content in mice.
Expired Air Study - Other Species Conduct a study to collect expired air and monitor its radioactivity content in other species.
Expired Air Study - Rat Conduct a study to collect expired air and monitor its radioactivity content in rats.

Show all 19 in In Vivo ADME 13 more

In Vivo Radiolabeled Metabolism Determine the qualitative and quantitative metabolism and/or degradation of an active ingredient in animals.
Mass Balance Study - Dog / Canine Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in dogs/canines.
Mass Balance Study - Minipig Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in minipigs.
Mass Balance Study - Monkey / Non-human Primate Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in monkeys/non-human primates.
Mass Balance Study - Other Species Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in other species.
Mass Balance Study - Rat Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in rats.
Milk Secretion Study - Other Species Conduct a study to determine the extent of milk secretion of your radioactive compound in other species.
Milk Secretion Study - Rat Conduct a study to determine the extent of milk secretion of your radioactive compound in rats.
Ocular Distribution Study - Rat Conduct a study to determine the distribution of your compound in ocular tissues of the rat.
Placental Transfer Study - Rabbit Conduct a study to determine the extent of placental transfer in rabbits by assessing the radioactivity of your compound in fetal tissue and maternal blood.
Placental Transfer Study - Rat Conduct a study to determine the extent of placental transfer in rats by assessing the radioactivity of your compound in fetal tissue and maternal blood.
Quantitative Whole Body Autoradiography (QWBA) Determine the tissue distribution of a radiolabeled compound in Rodent and Non-Rodent Species.
Quantitative Whole Body Autoradiography (QWBA) - Rodent Species (Mouse, Rat) Conduct a study to determine the tissue distribution of your compound radiolabeled compound in rodent species.

In Vivo Pharmacokinetics

In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
Mass Balance Elucidate excretory pathways and organ distribution of a parent drug and metabolites
Ocular Pharmacokinetic (PK) Screening - Other Species Conduct a pharmacokinetic screening study in other species that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.

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Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.

Lab Supplies, Facilities, and Equipment

Biobanking Store and track biological samples.

Market Access

Marketing and Commercialization Identify, promote and prove the value of a particular drug to key stakeholders.

Medical Communications

Gap Analysis Compare the actual performance of an organization or corporation with potential or desired performance, as ways to effectively analyze resource management or allocation.
Medical Publications Make clear and accurate presentations of scientific and technical data.

Model Development

Japanese White Rabbit Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
Knockout Mice Create transgenic mice that are genetically engineered to inactivate a gene or set of genes.
Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
NMRI Mouse Use a single animal species to create one or more disease models for cachexia and hemophilia.
Non-Human Primate Models Use a single animal species to create one or more disease models.
PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.

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SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.
Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Zebrafish Animal Model Model human disease and development in zebrafish.
Zucker Rat Use a single animal species to create one or more disease models for cachexia.

Non-Human Biospecimen

Dog / Canine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Dog / Canine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Dog / Canine Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Goat Cells, Tissues, and Biofluids Acquire fresh or frozen cells, tissues, and biofluids including but not limited to whole blood, PBMCs, tissue slides, etc.
Guinea Pig Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Guinea Pig Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.

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Guinea Pig Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Llama Cells, Tissues, and Biofluids Acquire fresh or frozen cells, tissues, and biofluids including but not limited to whole blood, PBMCs, tissue slides, etc.
Monkey / Non-Human Primate / NHP Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Monkey / Non-Human Primate / NHP Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Mouse Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Mouse Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Non-Human Biospecimen Finder Explore listings of Non-Human Biological Samples from the suppliers on the scientist.com NHBS database.
Pig / Minipig / Porcine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Pig / Minipig / Porcine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Pig / Minipig / Porcine Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Rabbit Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Rabbit Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Rabbit Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Rat Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
Rat Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Rat Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.

Old Category HEOR, RWE, Market Access

Commercialization and Marketing Identify, promote and prove the value of a particular drug to key stakeholders.

Oncology Models

3D Triculture Breast Cancer Model Use tricultures of breast cancer cell lines, hMSCs, and endothelial tubules for evaluating breast cancer progression.
Angiogenesis Models Measure therapeutic endpoints in animal models of angiogenesis.
Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.

Other Specialty Toxicology

Biosafety Testing Consulting Expert advice to conduct safe and responsible biological procedures and practices.
Phototoxicity Determine whether drug treatment causes light-activated toxic effects.

Pharmacovigilance

GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Product Development

Personal/Consumer Care Product or Service Request relating to the creation, testing or manufacturing of a personal care/consumer health/cosmetic product, ingredient or raw material.

Product Orders

Kits and Reagents Submit a request to multiple vendors for kits and reagents.

Protein Sciences

Cytokines Find recombinant cytokines or cytokine assays.
ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Protein Binding Determine drug-protein binding interactions
Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Yeast Two Hybrid Search novel interactions or confirm hypothesized protein-protein interactions using pairwise assays.

Radioanalysis

Stand-alone Radioanalysis of Animal Pre-clinical Samples Conduct analysis of radioactive samples from preclinical radiolabeled studies.
Stand-alone Radioanalysis of Human Clinical Samples Conduct analysis of radioactive samples from clinical metabolism radiolabeled studies.

Raw Materials

U.V. Absorbers Acquire U.V. absorbers, such as phenylbenzimidazole sulphonic acid and trolamine salicylate, to use as ingredients in consumer healthcare products.

REACH Services

In Vitro REACH Services Perform skin or eye irriation tests, sensitivily and geneotoxicity tests
In Vitro Skin Sensitization Determine whether a drug or cosmetic product may cause dermal sensitization.
In Vivo REACH Services Performing testing when in vitro studies cannot be used to predict biological responses
OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...
OECD 432: In Vitro 3T3 NRU Phototoxicity Test Test the cytotoxic effects of chemical substances and environmental samples on cell membranes.

Safety Pharmacology

Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.

Scientific Data Services

Strategic RFX Utilize the Scientist.com marketplace to run a strategic RFI/RFP to consolidate orders across different sites with preferred vendors, find new vendors, and leverage to negotiate better pricing.

Target Animal and Human Food Safety

Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.

Testing Services

Collagen Production Test Test the regenerative ability of the skin under the influence of the test sample.
In Vitro Claim Substantiation Evaluation using FDA Broad Spectrum and/ or ISO 24443
In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.
Membrane Permeability (PAMPA) Parallel Artificial Membrane Permeability Assay (PAMPA) - Measure passive diffusion of drugs by the parallel artificial membrane permeation assay.
OECD 439: Skin Irritation Test (SIT) Reconstructed Human Epidermis Test (RhE) Method - An in vitro testing method designed to identify chemicals and/or mixtures capable of inducing moderate skin irritation.

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OECD TG 492: Ocular Irritation Testing Use in vitro skin models to determine whether a product can cause dermal sensitization (e.g. EpiOcular Eye Irritation Test - EIT)
Phototoxicity and Photosensitization Screening Screen a consumer healthcare product for irritancy and/or allergy potential following exposure to UV light.
Phototoxicology Phototoxicity testing identifies and evaluates the potential of chemical agents to induce toxicity upon subsequent exposure to light.
Skin Lightening Product Test Measure qualitative and quantitative changes in skin pigmentation under the influence of the test sample.
SPF Protection Efficacy Evaluation using FDA Final Rule (2011), Cosmetics Europe (COLIPA), ISO 24444
UVA Protection Efficacy Evaluation of UVA protection using JCIA or ISO 24442

Other services

Biological Material For requesting cells and other propagatable material.
Geneknown™ Pooled Human Hepatocytes Study the effects of specific genetic variants on drug metabolism and transport.
Human Dendritic Cell (hDC) Model Test and validate the immune-modulating compounds in DC immune pathway models.
In Vitro Neurodegenerative Disease Platform Use an IVND platform to screen different compounds/drugs in a finely controlled synaptopathies scenario.
IND Writing Receive assistance with materials for an IND application.
Medical Device Product Certification Ensure local and global regulatory standards are met for product certification.

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NDA Writing Receive assistance in the NDA application process.
New Request

Service areas:

Biology

United States Baltimore, Woodbury, Detroit, Kansas City, Santa Clara 7 sites
Belgium Schaerbeek 2 sites
Germany Frankfurt am Main 1 site
United Kingdom Burgess Hill 1 site

In July 2014, BioreclamationIVT acquired Sera Laboratories. Seralab is now a division of BioreclamationIVT and offers the same products as before and more. Seralab, a division of BioreclamationIVT, handles European accounts while BioreclamationIVT oversees North American accounts. BioreclamationIVT is a worldwide provider of biological and in vitro products to pharmaceutical and biotechnology organizations. We specialize in control and disease state matrices manufactured from human and animal blood, plasma and serum, which are used in drug discovery, compound development, clinical...

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BioreclamationIVT is a worldwide provider of biological and in vitro products to pharmaceutical and biotechnology organizations. We specialize in control and disease state matrices manufactured from human and animal blood, plasma and serum, which are used in drug discovery, compound development, clinical and research diagnostics. We can immediately add value to your drug discovery and preclinical development program by providing large lot of hepatocytes, other cell types, and subcellular fractions along with associated media. BioreclamationIVT's products enable scientists and biomedical researchers to better understand the pharmacokinetics and drug metabolism of newly discovered compounds and the effects on disease processes.

Seralab is a major supplier of quality animal sera and biological products to the cell culture and biopharma industries for use in such disciplines as cell biology, genomics, proteomics, virology, immunology, drug discovery and toxicology. Our technical and managerial staff have over 20 years of experience in serum and antibody production offering our customers reliability, full traceability and extensive quality control. We offer the most extensive range of animal based products in Europe from a wide variety of origins. In addition, Seralab offers a contract manufacture service for the supply of any serum and plasma products. At Seralab we continue to focus on the traditional values of quality product, competitive pricing and absolute customer care.

Professional associations: MassBio
Website: www.bioivt.com

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