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BioVariance
BioVariance is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 3 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
Clinical Consulting
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Data Science/Bioinformatics
- In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
- In Silico Drug-Drug Interactions Use computational tools to predict pharmaceutical, pharmacodynamic or pharmacokinetic drug-drug interactions to maximize drug regimen safety.
- In Silico Epigenetic Compound Library Screening Use computer-aided methods to discover new compounds against key regulators of epigenetic signaling.
- In Silico Nucleic Acid Microarray Analysis Use software to visualize and evaluate gene activity in response to various stimuli.
- In Silico Protein Microarray Analysis Use software to visualize and evaluate protein function and expression on a large scale.
- In Silico Protein Modification Analysis Use computational methods to predict the behavior of modified proteins.
Show all 7 in Data Science/Bioinformatics
- In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.
Show all 40 services
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
- In Silico Metabolite Predictions Conduct in silico assessment of metabolite pharmacokinetic properties and potential exposure effects.
- Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Disease Models
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
Drug Development
- Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.
- Structural Chemistry Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
General Marketing
- Database Management Software Facilitate the collection, tracking and processing of biological facts, statistics and observations.
In Vitro ADME
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
- Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
In Vitro Pharmacology
- Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
- Target Identification Identify the target(s) of a biologically active substance.
Safety Pharmacology
- Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- Data and Text Mining Derive structured data from free text in order to become accessible for data-mining algorithms.
- Database Integration Convert bioinformatics results from multiple data sources (DSs) into a single operational format.
- Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
- In Silico Genomics/Transcriptomics Data Analysis Interpret DNA sequencing and microarray data.
- In Silico Metagenomics/Metatranscriptomics Data Analysis Use software to analyze genomic information from multiple environmental sources.
Show all 10 in Scientific Data Services
- Software Tools Software tool for statistical analysis, data mining, genome annotation or NGS data analysis.
- Systems Biomedicine Analyze complex interactions in biological systems with interdisciplinary scientific teams.
- Systems Network Analysis Analyze and visualize molecular pathways including gene regulatory, protein-protein and drug-target networks.
- Systems Pharmacology Understand how drugs interact with different molecular and cellular systems within biological models.
Service areas:
Where it operates
Sites by country, with the cities in each.
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Germany 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
BioVariance provides analysis services for Translational Research, Bioinformatics, Cheminformatics All our analysis services are enhanced by well-integrated background knowledge from scientic databases, i.e. in addition to your data the analyses and results are put in context with most recent knowledge. The core focus is at the area where xenobiotics meet human biology. The analyses are provided in three different areas, I put a few examples on each one and will be happy to discuss in more detail: +Drug Discovery+ Off-Target & side effect prediction for compounds Developing hypotheses...
Show the full description
BioVariance provides analysis services for Translational Research, Bioinformatics, Cheminformatics
All our analysis services are enhanced by well-integrated background knowledge from scientic databases, i.e. in addition to your data the analyses and results are put in context with most recent knowledge. The core focus is at the area where xenobiotics meet human biology. The analyses are provided in three different areas, I put a few examples on each one and will be happy to discuss in more detail:
+Drug Discovery+
- Off-Target & side effect prediction for compounds
- Developing hypotheses for unwanted toxicities
+Translational Data Analysis+
- Indication expansion
- Pathway-based biomarkers
- NGS/Expression/Mutation analyses
+General consulting+
- all areas above
- visualizing complex data
- Website
- www.biovariance.com
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