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iPhase Pharma Services
iPhase Pharma Services is listed as a small business research supplier in the Scientist.com network, with 4 sites in 2 countries and 4 service areas.
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Sites
4
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
Biomarkers
- Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Chemical and Compound Analysis
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Show all 103 services
Chemistry, Manufacturing and Controls (CMC)
- Subcellular Fraction Test System Obtain human, minipig, mouse, or rat dermal microsomes as in-stock standard test systems for the development of safer topical and transdermal products.
Discovery Chemistry
- Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
Disease Models
- Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.
Drug Development
- Small Molecule Drug Development Consulting Request consulting services related to small molecule development.
General in vivo Toxicology
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
- Human Biofluids Acquire fresh/frozen biofluids based on patient demographics, disease stage, history and treatment.
- Human Biopsy Cell Models Request human biopsy cell models.
- Human Blood Acquire fresh/frozen human blood based on patient demographics, disease stage, history and treatment.
Show all 22 in Human Biological Samples
- Human Bone Marrow Cells Acquire fresh, frozen, or fixed normal bone marrow based on patient demographics and history.
- Human Cell Products For requesting human cell by products like proteins, lysates, lysosomes etc
- Human Endothelial Cells Endothelial cells are specialized epithelial cells that form a single layer lining the inner surface of all blood vessels and lymphatic vessels
- Human Epithelial Cells Human epithelial cells are the most abundant cell type in the body and form the outer layer of skin and line various internal organs, including the digestive and respiratory tracts.
- Human Frozen Tissue For requesting frozen human tissue.
- Human Hepatocytes Acquire human hepatocytes isolated from the liver.
- Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
- Human Microsomes Acquire microsomes derived from the endoplasmic reticulum of hepatic cells
- Human Neural Stem Cells Acquire human neural stem cells isolated from brain tissue.
- Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
- Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
- Human Plasma Acquire fresh/frozen human plasma
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
- Human Red Blood Cells Acquire fresh/frozen normal red blood cells based on patient demographics and history.
- Human Tears Acquire fresh/frozen Tears based on patient demographics, disease stage, treatment and history.
- Human Whole Organs Procure non-transplantable whole human organs or tissues, healthy or diseased, for medical research and development.
In Vitro ADME
- Cell Fractionation Isolate organelles and subcellular components.
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
- Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
Show all 16 in In Vitro ADME
- In Vitro ADME in Vitro ADME services
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
- Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
- Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
- Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
In Vitro Toxicology
- Genotoxicity Evaluate potential of a compound to cause mutations and chromosomal aberations
In Vivo ADME
- Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
- Mass Balance Study - Monkey / Non-human Primate Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in monkeys/non-human primates.
- Mass Balance Study - Other Species Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in other species.
- Mass Balance Study - Rat Conduct a study to investigate the plasma pharmacokinetics and excretion of your compound as well as total radioactivity in rats.
In Vivo Pharmacokinetics
- Ocular Pharmacokinetic (PK) Screening - Dog / Canine Conduct a pharmacokinetic screening study in dogs/canines that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
- Ocular Pharmacokinetic (PK) Screening - Rat Conduct a pharmacokinetic screening study in rats that measures the absorption, distribution, metabolism and excretion of your compound following ocular administration.
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
- Pharmacokinetic (PK) Screening - Dog / Canine Run pharmacokinetic studies in dogs that measure a drug’s absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Monkey / Non-human Primate Conduct a pharmacokinetic screening study in monkeys/non-human primates that measures the absorption, distribution, metabolism and excretion of your compound.
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Show all 8 in In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Non-Human Biospecimen
- Dog / Canine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Dog / Canine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Dog / Canine Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
- Goat Cells, Tissues, and Biofluids Acquire fresh or frozen cells, tissues, and biofluids including but not limited to whole blood, PBMCs, tissue slides, etc.
- Guinea Pig Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Guinea Pig Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
Show all 24 in Non-Human Biospecimen
- Guinea Pig Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
- Llama Cells, Tissues, and Biofluids Acquire fresh or frozen cells, tissues, and biofluids including but not limited to whole blood, PBMCs, tissue slides, etc.
- Monkey / Non-Human Primate / NHP Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Monkey / Non-Human Primate / NHP Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Monkey / Non-Human Primate / NHP Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
- Mouse Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Mouse Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
- Pig / Minipig / Porcine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Pig / Minipig / Porcine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Pig / Minipig / Porcine Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
- Rabbit Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Rabbit Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Rabbit Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
- Rat Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Rat Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Rat Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
- Zebrafish Cells, Tissues, and Biofluids Acquire fresh or frozen cells, tissues, and biofluids including but not limited to whole blood, PBMCs, tissue slides, sperm, etc.
Product Orders
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Protein Sciences
- Protein Binding Determine drug-protein binding interactions
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
REACH Services
- OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
- OECD 473: In Vitro Mammalian Chromosomal Aberration Test Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
- OECD 476: In Vitro Mammalian Cell Gene Mutation Test (Mouse Lymphoma Assay) Determine if a compound is mutagenic by using cultured mammalian cells.
- OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Safety Pharmacology
- Tissue Cross Reactivity Assess the toxic effects of humanized monoclonal antibodies in 33 normal types recommended by the FDA.
Testing Services
- Bacterial Reverse Mutation Assay Test whether a cosmetic product or ingredient causes DNA mutations in bacteria.
Other services
- New Request
Service areas:
Biology
DMPK
Pharmacology
Toxicology
Where it operates
Sites by country, with the cities in each.
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United States 3 sites
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China 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
iPhase Pharma Service (IPS) is a Contract Research Organization (CRO) founded by a group of professionals from US pharmaceutical and contract service industries. iPhase Pharma Services offers broad and integrated services for pharmaceutical and biotechnology companies. With our state-of-the-art instruments, AAALAC accredited GLP facility, Phase I clinical center, and professional team in nonclinical, clinical, and bioanalysis, we provide our partners optimal outsourcing solutions ranging from drug discovery, drug metabolism and pharmacokinetics, clinical bioavailability/bioequivalence...
Show the full description
iPhase Pharma Service (IPS) is a Contract Research Organization (CRO) founded by a group of professionals from US pharmaceutical and contract service industries. iPhase Pharma Services offers broad and integrated services for pharmaceutical and biotechnology companies. With our state-of-the-art instruments, AAALAC accredited GLP facility, Phase I clinical center, and professional team in nonclinical, clinical, and bioanalysis, we provide our partners optimal outsourcing solutions ranging from drug discovery, drug metabolism and pharmacokinetics, clinical bioavailability/bioequivalence, and bioanalytical services.
- Website
- www.iphasebiosci.com
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