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Ambiotis
Ambiotis is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Membrane Lipidomics Study the pathways and networks of membrane lipids.
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
- Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
Show all 16 in Biomarkers
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Histamine Release Assay Use in vivo or in vitro assays to measure the release of histamine in response to an allergen stimulation.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Lipid Peroxidation Assay Use in vitro or in vivo assays to evaluate the effects of oxidative stress on lipid structure and function.
- Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
- Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
- Single Cell quantitative Real Time-PCR Assess gene expression levels and patterns in a single cell.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
Chemical and Compound Analysis
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Disease Models
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Inflammatory Bowel Disease Models Measure IBD symptom severity, cytokine levels and body weight, and evaluate IHC and Ariol images.
- Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
Show all 38 services
Human Biological Samples
- Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Show all 8 in In Vitro Assays
- Lipolysis Measure the hydrolysis of triglycerides into glycerol and free fatty acids.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
Service areas:
Where it operates
Sites by country, with the cities in each.
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France 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Ambiotis is a pre-clinical CRO focused on inflammation and with a worldwide recognized expertise on the resolution phase of inflammation. The company has developed a state-of-the-art technology platform and is offering a wide range of services : - a set of in vivo and in vitro models (human primary cells) to evaluate anti-inflammatory, pro-resolutive or immuno-modulatory properties of a variety of entities (molecule candidate, vaccine components...) and perform their proof of concept. Covered therapeutic areas include intestinal diseases, metabolic disorders, arthritis, fibrosis...
Show the full description
Ambiotis is a pre-clinical CRO focused on inflammation and with a worldwide recognized expertise on the resolution phase of inflammation.
The company has developed a state-of-the-art technology platform and is offering a wide range of services :
- a set of in vivo and in vitro models (human primary cells) to evaluate anti-inflammatory, pro-resolutive or immuno-modulatory properties of a variety of entities (molecule candidate, vaccine components...) and perform their proof of concept.
Covered therapeutic areas include intestinal diseases, metabolic disorders, arthritis, fibrosis, respiratory diseases, infectious diseases, skin diseases, cancer...
- a core expertise in lipidomics targeting inflammatory mediators (prostaglandines,...), specialized pro-resolving mediators (SPM) (lipoxins, resolvins, protectins, maresin...) and endocannabinoids. Our method based on LC/MS/MS technology allows the detection and quantification of lipid biomarkers in various kinds of samples (cell supernatants, serum, plasma, urine, tissues...) thus allowing it to be used in both preclinical and clinical studies.
- Website
- www.ambiotis.com
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