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Human Metabolome Technologies (HMT)
Human Metabolome Technologies (HMT) is listed as a mid sized business research supplier in the Scientist.com network, with 4 sites in 3 countries and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Biomarkers
- Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Complete Metabolic Panel Testing Detect electrolyte or glucose imbalance to identify or monitor related disorders.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
Show all 12 in Biomarkers
- Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
Cell Culture and Characterization
- Cell Culture Culture primary or immortalized cell lines.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Clinical Consulting
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Disease Models
- Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
Effectiveness
- In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
Show all 36 services
Human Biological Samples
- Human Fecal Matter Acquire fresh/frozen normal feces based on patient demographics and history.
- Human Plasma Acquire fresh/frozen human plasma
- Human Saliva Acquire fresh/frozen normal saliva based on patient demographics and history.
- Human Serum Acquire fresh/frozen normal serum based on patient demographics and history.
- Human Urine Acquire fresh/frozen normal urine based on patient demographics and history.
- Human Vaginal Fluid/ Swab Acquire fresh/frozen normal vaginal fluid based on patient demographics and history.
In Vitro ADME
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
In Vitro Assays
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Fully Automated Assays Develop and perform assays that require no manual steps
- Microbiology Study microbes and their role in human health.
- Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Target Characterization Characterize potential drug targets during the drug discovery process.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
Protein Sciences
- Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 2 sites
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Japan 1 site
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Netherlands 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Human Metabolome Technologies (HMT) is a Japan-based biotechnology company developing capillary electrophoresis mass spectrometry (CE-MS) based metabolomics technologies and solution to drive drug discovery, companion diagnostics (Biomarkers), and food production. Our research and development methodology are at the heart of an emerging field of metabolomics and systems biology. HMT can identify more than 1,000 species of metabolites by the metabolome analysis technology using CE-MS. In addition, HMT develops an original software analysis platform along with the measuring technologies, such...
Show the full description
Human Metabolome Technologies (HMT) is a Japan-based biotechnology company developing capillary electrophoresis mass spectrometry (CE-MS) based metabolomics technologies and solution to drive drug discovery, companion diagnostics (Biomarkers), and food production. Our research and development methodology are at the heart of an emerging field of metabolomics and systems biology. HMT can identify more than 1,000 species of metabolites by the metabolome analysis technology using CE-MS. In addition, HMT develops an original software analysis platform along with the measuring technologies, such as CE-MS, LC-MS, and MS/MS, that we have newly developed for the realization of metabolome analysis. Furthermore, we aim to develop a faster metabolome analysis technology with higher sensitivity and higher efficiency by collaboration with the Institute for Advanced Biosciences (IAB), Keio University. HMT’s primary business aims to provide complete solution for biomarker studies and metabolome analysis in drug design, diagnostic technology, and food production, using wide range of targets including human and animal samples — we thus call ourselves as “metabolomics provider.”
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- Website
- en.humanmetabolome.com
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