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Aviva Biosciences
Aviva Biosciences is listed as a new startup research supplier in the Scientist.com network, with 1 site in 1 country and 3 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Chemical and Compound Analysis
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Disease Models
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Ventricular Tachycardia Models Measure therapeutic endpoints in animal models of ventricular tachycardia.
DNA & RNA
- RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
In Vitro Assays
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
In Vitro Pharmacology
- Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
- Potassium Channel Assays Use biochemical, cell-based or in vivo assays to measure potassium channel activity.
- Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
Show all 7 in In Vitro Pharmacology
- Sodium Channel Assays Use biochemical, cell-based or in vivo assays to measure sodium channel activity.
Show all 25 services
In Vitro Toxicology
- Cardiac Channels Measure the arrhythmia producing potential of test compounds.
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
- Cytotoxicity Test for effects on cell viability and proliferation
Model Development
- Fresh Functional Human Tissue Ion Channel Activity Assays Use fresh functional human tissue to assess ion channel activity with various compounds.
- Fresh Functional Human Tissue Muscle Contraction Assays Use fresh functional human tissue to assess muscle contraction with various compounds.
- Fresh Functional Human Tissue Muscle Relaxation Assays Use fresh functional human tissue to assess muscle relaxation with various compounds.
- Fresh Functional Human Tissue Vasoconstriction Assays Use fresh functional human tissue to assess vasoconstriction with various compounds.
- Fresh Functional Human Tissue Vasodilation Assays Use fresh functional human tissue to assess vasodilation with various compounds.
Safety Pharmacology
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Other services
- RNA Isolation Purify RNA from pre-clinical and clinical samples.
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Aviva Biosciences provides electrophysiological and ion channel drug screening services. Our clients also benefit from the full support of our bank of automated electrophysiology instruments, highly qualified and experienced personnel and reliable and timely customer service. Conventional electrophysiology assays are also available upon request. Aviva Biosciences can evaluate cardiac and vascular safety of experimental compounds using in vitro human tissue assays. These studies eliminate all concerns about cross species pharmacological differences and represent an efficient and cost...
Show the full description
Aviva Biosciences provides electrophysiological and ion channel drug screening services. Our clients also benefit from the full support of our bank of automated electrophysiology instruments, highly qualified and experienced personnel and reliable and timely customer service. Conventional electrophysiology assays are also available upon request.
Aviva Biosciences can evaluate cardiac and vascular safety of experimental compounds using in vitro human tissue assays. These studies eliminate all concerns about cross species pharmacological differences and represent an efficient and cost effective approach to first-in-human safety. We have also developed a set of tools and protocols that allow the ultra-rapid generation of new custom cell lines. Up to 3 different polypeptides can be co-expressed in each cell line. This revolutionary approach allows us to provide our customers with new cell lines in as little as three weeks.
- Website
- www.avivabio.com
Work with Aviva Biosciences on Scientist.com
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