- Supplier site
- Group of sites (click to zoom)
Scientist.com supplier network (site locations)
Research supplier
PharmaCadence
PharmaCadence is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 1 service area.
View PharmaCadence on Scientist.com
Email me this page as a PDF
Sign in to Scientist.com to open this supplier in your organization's marketplace.
Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Sites
2
Countries
1
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Peptide Bioanalysis Analyze the structure of Peptides.
- Protein Bioanalysis Quantitative measurement of xenobiotics (drugs and their metabolites, and biological molecules in unnatural locations or concentrations) and Proteins in biological systems
- Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Chemical and Compound Analysis
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Show all 7 in Chemical and Compound Analysis
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Clinical Consulting
- Bioanalysis Consulting Expert advice to properly and effectively discover, evaluate, and measure chemical or biological materials.
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Show all 45 services
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Drug Metabolism and Pharmacokinetics (DMPK)
- Biomarkers DMPK Biomarker DMPK and gene analysis services are critical tools in evaluating patients and discovery of new therapeutics.
In Vitro ADME
- Blood Brain Barrier Measure movement of drugs from circulating blood to brain extracellular fluid.
- Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
- Conjugate Detection Measure the conjugation of endogenous small molecules to drug candidates after in vivo administration.
- Intestinal Permeability Use Caco 2 and MCDK cells to assess mono-directional drug transport by passive diffusion in culture.
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
Show all 15 in In Vitro ADME
- Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
- Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- Multidrug Resistance Identify potential causes of drug-drug interactions.
- Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
- Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
- Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
In Vitro Pharmacology
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
- UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.
In Vitro Toxicology
- Zebrafish Embryo Toxicity Use a single animal species to create one models of toxicity.
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Protein Sciences
- LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
- Phosphorylation Analysis Identify phosphorylation sites in target proteins.
- Protein Binding Determine drug-protein binding interactions
- Quantitative MS Quantify small and large molecules in the pg/ml range
Other services
- New Request
Service areas:
DMPK
Where it operates
Sites by country, with the cities in each.
-
United States 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
PharmaCadence is an analytical research services organization serving the pharmaceutical and life sciences fields with expert LC-MS services. We specialize in high quality quantitative LC-MS bioanalytical methods for research and early development. Our service offerings include protein and peptide quantitative LC-MS analysis, as well as a full range of ADME in vitro assays along with the complete suite of preclinical pharmacokinetics capabilities.
- Professional associations
- AAPS, ACS, PABio
- Website
- www.pharmacadence.com
Work with PharmaCadence on Scientist.com
For prices, more details, or to contact PharmaCadence, visit Scientist.com.
Sign in to Scientist.com to open this supplier in your organization's marketplace.