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BioAgilytix Labs
BioAgilytix Labs is listed as a mid sized business research supplier in the Scientist.com network, with 7 sites in 2 countries and 1 service area.
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Sites
7
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Anatomic Pathology
- Immunohistochemistry Services Prepare, stain and label with histological and immunological reagents, then evaluate slide preparation of cells or tissue.
Antibodies
- Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
- Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
Biomarkers
- Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
- Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
Show all 17 in Biomarkers
- Cytogenetics Examine the structure and function of the cell, especially chromosomes.
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- NBE Biomarkers Request information or a price quote for NBE Biomarkers services
- Osteoclasts Measure osteoclast activity and bone resorption in human, mouse or rat assays.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
Cell Culture and Characterization
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
Show all 110 services
Chemical and Compound Analysis
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Show all 9 in Chemical and Compound Analysis
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Chemical and Compound Testing
- Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
- Regulatory Consulting Ensure that each product or device complies with all FDA rules and regulations.
Clinical Trials
- Bioequivalence Studies Assess the expected biological equivalence of two proprietary preparations of a drug.
Data Science/Bioinformatics
- Clinical Data Management A process that includes acquiring, validating, storing, protecting, and processing required data to ensure the accessibility, reliability, and timeliness of the data.
Discovery Chemistry
- Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
- Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...
Disease Models
- Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
- Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.
DNA & RNA
- qPCR Analysis Measure the accumulation of PCR products in real time.
- RNA Amplification Produce RNA from pre-clinical and clinical samples for use in gene expression studies.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Drug Metabolism and Pharmacokinetics (DMPK)
- Biomarkers DMPK Biomarker DMPK and gene analysis services are critical tools in evaluating patients and discovery of new therapeutics.
In Vitro ADME
- Cell Fractionation Isolate organelles and subcellular components.
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
- Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
Show all 19 in In Vitro ADME
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
- Metabolite Generation Analyze the formation of drug metabolites after administration of drug to an animal model or patient.
- Metabolite Identification Identify drug metabolites that are formed after administration of drug to an animal model or patient.
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
- Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
- Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
- Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
- Protein Binding Ultrafiltration Measure the rate at which unbound drug passes through a dialysis membrane that models epithelial barrier pore size.
- Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
Show all 10 in In Vitro Assays
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Monoamine Transporter Assays Measure monoamine neurotransmitter uptake in cultured cells.
- Pathway Mapping Define mechanisms of action by analyzing protein pathways affected by drug treatment.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
In Vitro Pharmacology
- Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
- Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Show all 17 in In Vitro Pharmacology
- Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
- Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
- Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
- Phosphodiesterase Assays Measure phosphodiesterase activity in biochemical and cell-based assays.
- Protease Assay Measure protease activity in biochemical and cell-based assays.
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
- Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
- Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
- Ubiquitin Ligase Assays Measure ligase enzyme activity in the presence of cofactors or chemical modifiers.
- UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
- Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Medical Communications
- Quality Control/ Quality Assurance Documents Develop quality control or quality assurance documents.
Nanotechnology
- Drug Delivery Technology Create microstructures that enhance drug metabolism properties.
Pharmacovigilance
- GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.
Product Orders
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Phosphorylation Analysis Identify phosphorylation sites in target proteins.
- Protein Binding Determine drug-protein binding interactions
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Other services
- New Request
Service areas:
Biology
Where it operates
Sites by country, with the cities in each.
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United States 5 sites
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Germany 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
BioAgilytix is a leading contract research organization (CRO) specializing in large-molecule bioanalysis, offering PK, immunogenicity, biomarkers, and cell-based assays under GLP, GMP, fit-for-purpose, and discovery. BioAgilytix provides quality & efficient science with proven results from discovery to clinical trials, manufacturing, and post-marketing surveillance. Our veteran scientists and experienced Quality Assurance department work in sync to guarantee reliable and reproducible data of the highest quality. BioAgilytix ensures high quality science, sample and data integrity...
Show the full description
BioAgilytix is a leading contract research organization (CRO) specializing in large-molecule bioanalysis, offering PK, immunogenicity, biomarkers, and cell-based assays under GLP, GMP, fit-for-purpose, and discovery. BioAgilytix provides quality & efficient science with proven results from discovery to clinical trials, manufacturing, and post-marketing surveillance. Our veteran scientists and experienced Quality Assurance department work in sync to guarantee reliable and reproducible data of the highest quality.
BioAgilytix ensures high quality science, sample and data integrity, and regulatory compliance through the use of an exclusive operational model coupled with dedicated systems and procedures. Our bioanalytical project management model engages senior lab leads in program management, ensuring clear and transparent collaboration on your project. Our unique tracking and backup systems are highly advanced, guaranteeing sample security and data integrity. Finally, our Quality Assurance team is experienced in all GxP areas, making certain that your study is performed to industry quality standards. Together, these operational methods allow BioAgilytix to promise quality science on-time and on-budget and have enabled us to become a trusted partner to 6 out of the top 10 global pharmaceutical and biotech companies.
- Website
- www.bioagilytix.com
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