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CIC bioGUNE
CIC bioGUNE is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
- Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
- Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
- Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
- In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
- Rabbit Monoclonal Antibody Development Develop monoclonal antibodies using rabbit as the host animal.
Bioimaging
- Ab-Targeted Positron Emission Tomography Visualize sites of HIV replication that are difficult to access by tissue biopsies.
- Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
- Cryo Electron Microscopy Examine the 3D structure of biological complexes and organelles.
- Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
- In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
- In Vivo Whole Tissue and Animal Imaging Analysis Analysis of images from in vivo studies produced using PET, MRI, CT, etc. in a variety of species.
Show all 77 services
Biomarkers
- Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Cell Membrane Lipidomics Study the pathways and networks of membrane lipids.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Show all 19 in Biomarkers
- Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
- Protein Glycosylation Mapping Technique Map glycosylation sites in proteins using liquid chromatography and mass spectrometry.
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
- TUNEL Assay Detect in situ DNA fragmentation.
Cell Culture and Characterization
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.
Chemical and Compound Analysis
- Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
- MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Structural Chemistry Examine the relationship between protein structure and function.
- Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
- Structural Spectroscopy Assess conformational transitions that proteins undergo in response to changes in their environment.
Clinical Consulting
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
Data Science/Bioinformatics
- Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
- In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
DNA & RNA
- ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
- Metagenomic Sequencing Sequence genetic material recovered directly from environmental samples
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
- Whole Genome Amplification (WGA) Amplify an entire genome from a single cell.
- Whole Genome Sequencing Determine the entire genetic make-up of an organism.
Drug Development
- Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.
Human Biological Samples
- Human Biofluids Acquire fresh/frozen biofluids based on patient demographics, disease stage, history and treatment.
- Human Plasma Acquire fresh/frozen human plasma
- Human Serum Acquire fresh/frozen normal serum based on patient demographics and history.
In Vitro ADME
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.
In Vitro Pharmacology
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
- Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
- Protease Assay Measure protease activity in biochemical and cell-based assays.
- Target Identification Identify the target(s) of a biologically active substance.
Nanotechnology
- Nanoparticle Synthesis Create nano-level structures with unique features.
Protein Sciences
- Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Cytokines Find recombinant cytokines or cytokine assays.
- Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
- Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
- Phosphorylation Analysis Identify phosphorylation sites in target proteins.
Show all 10 in Protein Sciences
- Protein Purification Isolate native or recombinant proteins from a sample.
- Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
- X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
- Cancer Systems Biology Convert complex molecular data obtained from high-throughput technologies to deducible information.
- Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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Spain 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
CIC bioGUNE provides electron microscopy, crystallography, genomics, metabolics, and proteomics services.
- Website
- www.cicbiogune.es
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