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CIC bioGUNE

CIC bioGUNE is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.

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Sites 2
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Antibodies

  • Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
  • Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
  • Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
  • Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
  • In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
  • Rabbit Monoclonal Antibody Development Develop monoclonal antibodies using rabbit as the host animal.

Bioimaging

  • Ab-Targeted Positron Emission Tomography Visualize sites of HIV replication that are difficult to access by tissue biopsies.
  • Confocal/Optical Microscopy Use optical imaging technique to increase optical resolution and contrast of a micrograph.
  • Cryo Electron Microscopy Examine the 3D structure of biological complexes and organelles.
  • Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.
  • In Vivo Whole Tissue and Animal Imaging Visualize, analyze and track light producing reporters in whole animals.
  • In Vivo Whole Tissue and Animal Imaging Analysis Analysis of images from in vivo studies produced using PET, MRI, CT, etc. in a variety of species.
Show all 77 services 65 more

Biomarkers

  • Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
  • Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
  • Cell Membrane Lipidomics Study the pathways and networks of membrane lipids.
  • Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
  • Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Show all 19 in Biomarkers 13 more
  • Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
  • Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
  • Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
  • Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
  • Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
  • Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
  • Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
  • Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
  • Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
  • Protein Glycosylation Mapping Technique Map glycosylation sites in proteins using liquid chromatography and mass spectrometry.
  • Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
  • TUNEL Assay Detect in situ DNA fragmentation.

Cell Culture and Characterization

  • Bacterial Cell Culture Culture and Grow bacterial cells.
  • Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
  • Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
  • RNA-Based Transfection Deliver RNA to cells by microinjection, electroporation or lipid-mediated transfection.

Chemical and Compound Analysis

  • Dynamic Light Scattering Determine the size of particles and extent of molecular aggregation in a suspension.
  • MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
  • Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
  • Structural Chemistry Examine the relationship between protein structure and function.
  • Structural Elucidation Determine chemical structure of a compound. Characterization techniques include mass spectrometry, infrared spectroscopy and X-ray crystallography.
  • Structural Spectroscopy Assess conformational transitions that proteins undergo in response to changes in their environment.

Clinical Consulting

  • Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.

Data Science/Bioinformatics

  • Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
  • In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.

DNA & RNA

  • ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
  • Metagenomic Sequencing Sequence genetic material recovered directly from environmental samples
  • RNA Extraction Isolate total RNA or mRNA from cells or tissues
  • Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
  • Whole Genome Amplification (WGA) Amplify an entire genome from a single cell.
  • Whole Genome Sequencing Determine the entire genetic make-up of an organism.

Drug Development

  • Target Validation Consulting Help to demonstrate that modification of target activity has potential therapeutic benefits.

Human Biological Samples

  • Human Biofluids Acquire fresh/frozen biofluids based on patient demographics, disease stage, history and treatment.
  • Human Plasma Acquire fresh/frozen human plasma
  • Human Serum Acquire fresh/frozen normal serum based on patient demographics and history.

In Vitro ADME

  • Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
  • Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.

In Vitro Assays

  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.

In Vitro Pharmacology

  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.
  • Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
  • Protease Assay Measure protease activity in biochemical and cell-based assays.
  • Target Identification Identify the target(s) of a biologically active substance.

Nanotechnology

  • Nanoparticle Synthesis Create nano-level structures with unique features.

Protein Sciences

  • Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
  • Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
  • Cytokines Find recombinant cytokines or cytokine assays.
  • Immunoprecipitation Precipitate a protein of interest out of solution using an antibody to which it binds.
  • Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
  • Phosphorylation Analysis Identify phosphorylation sites in target proteins.
Show all 10 in Protein Sciences 4 more
  • Protein Purification Isolate native or recombinant proteins from a sample.
  • Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
  • X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.

Scientific Data Services

  • Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
  • Cancer Systems Biology Convert complex molecular data obtained from high-throughput technologies to deducible information.
  • Discovery Computational Systems Biology Model the interaction of biological system with drug candidates.

Other services

  • New Request  

Service areas:

Biology Chemistry

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Spain Derio 2 sites

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

CIC bioGUNE provides electron microscopy, crystallography, genomics, metabolics, and proteomics services.

Website
www.cicbiogune.es

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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