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Cincinnati Children's Hospital Medical Center Mouse Cytogenetics Core
Cincinnati Children's Hospital Medical Center Mouse Cytogenetics Core is listed as an academic core research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Academic core
Where it operates
Sites by country, with the cities in each.
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Chromosome karyotyping and molecular cytogenetics analyses play an important role in the study of chromosome abnormalities, genetic aberrations, cell line characterization and establishing disease models. The Mouse Cytogenetics Core at the Cincinnati Children’s Division of Human Genetics offers research investigators support for mouse classic karyotyping and molecular cytogenetic studies. Services include chromosome analysis of mouse tissues and cell lines, karyotype characterization of embryonic stem cells and induced pluripotent stem cells (iPSC), and locus copy number enumeration...
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Chromosome karyotyping and molecular cytogenetics analyses play an important role in the study of chromosome abnormalities, genetic aberrations, cell line characterization and establishing disease models.
The Mouse Cytogenetics Core at the Cincinnati Children’s Division of Human Genetics offers research investigators support for mouse classic karyotyping and molecular cytogenetic studies. Services include chromosome analysis of mouse tissues and cell lines, karyotype characterization of embryonic stem cells and induced pluripotent stem cells (iPSC), and locus copy number enumeration, refining chromosome breakage sites, and mapping of transgene integration sites.
Techniques available at the Mouse Cytogenetics Core include:
- Classical Cytogenetic Analyses
- Short-term cell culture / chromosome harvest
- Metaphase chromosome preparations
- G-banded karyotyping
- Breakage study
Fluorescence In Situ Hybridization (FISH)
- Interphase FISH
- Metaphase FISH
- FISH on paraffin-embedded tissues
- Multicolor FISH (M-FISH)
- Custom FISH probe development (BAC / PAC clone acquisition, BAC / PAC DNA isolation, nick translation / DNA labeling reaction)
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