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Institute for Biopharmaceutical Research (IBR)
Institute for Biopharmaceutical Research (IBR) is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 3 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
- Immunodetection Use antibodies to identify a protein or antigen.
Biomarkers
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
- Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Show all 16 in Biomarkers
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Histamine Release Assay Use in vivo or in vitro assays to measure the release of histamine in response to an allergen stimulation.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Interferon Gamma Release Assay Use in vivo or in vitro assays to measure the cell-mediated immune response to an infectious agent.
- Propidium Iodide FACS Analysis Use DNA staining and flow cytometry to analyze the cell cycle and detect apoptosis or cell proliferation.
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
- Wound Healing Assay Use cell-based assays to investigate cell proliferation, cell migration and wound closure.
Cell Culture and Characterization
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Bacterial Cell Culture Culture and Grow bacterial cells.
- Cell Culture Culture primary or immortalized cell lines.
Chemical and Compound Analysis
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Show all 70 services
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Clinical Consulting
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Discovery Chemistry
- Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
DNA & RNA
- PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
- RNA Extraction Isolate total RNA or mRNA from cells or tissues
Human Biological Samples
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
In Vitro Assays
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- BrdU S-Phase Analysis Assess cell division or apoptosis by measuring thymidine-analog label incorporation during DNA replication.
- Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Show all 14 in In Vitro Assays
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
- ELISpot Assay and Testing Detect low levels of antigens.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.
- Oxidative Burst Examine the release of reactive oxygen species (ROS) from neutrophils and other immune cells.
- Serine Protease Assay Detect apoptosis by measuring protease activity.
In Vitro Pharmacology
- ATP Competitive Study Determine whether or not a compound is competitive with ATP.
- B-Cell Lymphoma 2 (BCL-2) Assays Use biochemical, cell based or in vivo assays to measure BCL-2 protein activity.
- Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.
- Human Epidermal growth factor Receptor (HER) Assays Use biochemical, cell based or in vivo assays to measure HER receptor activity.
- In Vitro Hemolysis Assay Evaluate the toxicity of a drug, metabolite or excipient by hemolytic release of hemoglobin in the plasma.
- Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
Show all 9 in In Vitro Pharmacology
- Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
- Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.
- Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- CH50 Assays Measure the functional activity of the classical complement activation pathway in serum or other fluid samples.
- Cytotoxicity Test for effects on cell viability and proliferation
- Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
Management Optimization & Development Strategies
- OECD Regulatory Development Consultation in safety testing, chemical notification and registry within OECD.
Other Specialty Toxicology
- Residual DNA Analysis Measure contaminants found in therapeutics like biologicals and biosimilars that are produced in cells.
Protein Sciences
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Cytokines Find recombinant cytokines or cytokine assays.
- Protein Binding Determine drug-protein binding interactions
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
Safety Pharmacology
- Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
Switzerland 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
IBR Inc., Institute for Biopharmaceutical Research (IBR) is a science driven Swiss Contract Research Organisation with core competence in inflammation research and GLP compliant laboratories offering preclinical and clinical R&D services to biotechnology and pharmaceutical companies. Key areas of services are: • Cell-based assays for comparative potency determination of Biologics and Biosimilars • Reporter gene assays • Anti-Drug-Antibody assay development and validation • Cellular and humoral immunology and functional in-vitro analyses • ELISA development and validation Associated services...
Show the full description
IBR Inc., Institute for Biopharmaceutical Research (IBR) is a science driven Swiss Contract Research Organisation with core competence in inflammation research and GLP compliant laboratories offering preclinical and clinical R&D services to biotechnology and pharmaceutical companies.
Key areas of services are:
• Cell-based assays for comparative potency determination of Biologics and Biosimilars
• Reporter gene assays
• Anti-Drug-Antibody assay development and validation
• Cellular and humoral immunology and functional in-vitro analyses
• ELISA development and validation
Associated services
Residual host cell proteins
• Generic and host cell-specific ELISAs
• Isoelectric focussing, SDS PAGE and Western blotting
Method Development, Validation, Sample Analysis
Residual host DNA
• Production strain-specific qPCR methods
Method Development, Validation, Sample Analysis
Quality System
IBR Inc. is a current member of the Swiss GLP Compliance programme.
"Latest GLP audit by Swissmedic (Swiss Monitoring Authority): January 2014
- Website
- www.ibr-inc.com
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