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Research supplier
MedPharm
MedPharm is listed as a mid sized business research supplier in the Scientist.com network, with 4 sites in 2 countries and 5 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Cell Culture and Characterization
- Organotypic Culture Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
Chemical and Compound Analysis
- Chemical Stability Measure the stability of small molecules in solution.
- Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
- Photostability Measure drug degradation rates after exposure to various light sources.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Chemistry, Manufacturing and Controls (CMC)
- Analytical Development and Validation Request services related to Analytical Development and Validation
- API and Drug Product Stability Testing API and Drug Product Stability Testing.
- API and drug product storage and release API and drug product storage and release
- API Stress Testing Studies Develop analytical methods to predict stability problems and identify degradation products/pathways under forced degradation conditions.
- API/ Excipients Compatibility Studies Delineate real and possible interactions between potential formulation excipients and the API as an important risk reduction exercise early in formulation development.
- API/DP specific test methods API/DP specific test methods (e.g., stability indicating HPLC assay and purity)
Show all 17 in Chemistry, Manufacturing and Controls (CMC)
- Bulk Manufacturing Find facilities for large-scale mass production.
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Compendial test methods Run Compendial test methods (e.g., KF)
- Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
- Drug product packaging and labeling Drug product packaging and labelling
- Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
- Drug Repurposing Discovering new therapeutic uses for existing drugs that are outside the scope of the original medical indication.
- Drug Substance and Drug Product Characterization and Manufacturing Drug Substance and Drug Product Characterization and Manufacturing.
- Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
- ICH-compliant stability testing Perform ICH-compliant stability testing
- Salt Form Selection Use high-throughput automated arrays to combine APIs with multiple salts and ions to optimize formulation.
Show all 60 services
Disease Models
- Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
- Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
- Hair Growth Models Measure dermal histology, skin thickness, % anagen induction, hair proliferation and other hair growth markers.
- Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
- Microbiome-Based Skin Disease Technology Modify the skin microbiome and deliver therapeutic proteins to the target.
- Pain Model Consulting Expert advice to better evaluate and understand pain thresholds and phenomena within living organisms. Can be used to evaluate pain associated with specific diseases or injuries affecting the sensory and nervous systems.
Show all 8 in Disease Models
- Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
- Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.
In Vitro ADME
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- Nasal Permeability Test for passive diffusion and active transport in nasal permeability models.
- Skin Permeability Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
In Vitro Assays
- Assay Development Construct or create new assays or modify existing ones.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Pharmacology
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
In Vitro Toxicology
- Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
In Vivo Pharmacokinetics
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
Product Development
- Over-The-Counter (Other) - Manufacturing Other manufacturing services for Over-The-Counter (OTC) products
- Personal/Consumer Care Product or Service Request relating to the creation, testing or manufacturing of a personal care/consumer health/cosmetic product, ingredient or raw material.
- Specialty (Other) - Manufacturing Other manufacturing services for specialty products in personal care
REACH Services
- In Vitro Skin Sensitization Determine whether a drug or cosmetic product may cause dermal sensitization.
- OECD 405: Acute Eye Irritation/Corrosion This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye.
- OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...
Specialty Dosing Routes
- Dermal Toxicology Assess toxicity in rodent dermal testing models.
Testing Services
- Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
- Freeze-Thaw Testing Use freeze-thaw cycling to measure the long-term durability of cosumer products.
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
- OECD 428: In Vitro Skin Penetration Request OECD 428 services. This method is designed to provide information on absorption of a test substance, (ideally radiolabelled), applied to the surface of a skin sample separating the two chambers (a donor...
- OECD 435: Skin Corrosion Test - Membrane Barrier Method Use in vitro models to determine whether a cosmetic product or ingredient can cause skin corrosion.
- OECD 439: Skin Irritation Test (SIT) Reconstructed Human Epidermis Test (RhE) Method - An in vitro testing method designed to identify chemicals and/or mixtures capable of inducing moderate skin irritation.
Show all 11 in Testing Services
- OECD TG 492: Ocular Irritation Testing Use in vitro skin models to determine whether a product can cause dermal sensitization (e.g. EpiOcular Eye Irritation Test - EIT)
- Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
- Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.
- Skin Elasticity Testing Measure the skin's ability to resist pressure (firmness) and its ability to return to its original position pre- and post-treatment.
- Skin Lightening Product Test Measure qualitative and quantitative changes in skin pigmentation under the influence of the test sample.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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United States 3 sites
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United Kingdom 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
MedPharm is a world leading specialist contract service company committed to the creation and development of topical and transdermal formulations for application to the skin, nail, mucous membranes, eye, nose and lung. With over 150 customers worldwide, MedPharm offers a unique and highly specialised service in pharmaceutical contract research and development. Services range from pre-formulation and feasibility studies, through formulation development, efficacy and toxicity testing, all the way to the manufacturing of GMP clinical trails materials (up to phase II). The company operates...
Show the full description
MedPharm is a world leading specialist contract service company committed to the creation and development of topical and transdermal formulations for application to the skin, nail, mucous membranes, eye, nose and lung.
With over 150 customers worldwide, MedPharm offers a unique and highly specialised service in pharmaceutical contract research and development. Services range from pre-formulation and feasibility studies, through formulation development, efficacy and toxicity testing, all the way to the manufacturing of GMP clinical trails materials (up to phase II).
The company operates a hybrid business model, with a CRO business and a development programme with a substantial patent portfolio of novel topical and transdermal drug delivery systems. These systems include MedSpray®, MedTherm™ and AquaRMed. It has produced these innovations by exploiting its internal product development expertise, with a particular focus on dermatology. The company is actively seeking to license these technologies to third parties for developing their own compounds in non-competing indications. MedPharm’s laboratories in the UK meet the requirements for GMP and GLP.
- Professional associations
- AAPS, RSC
- Website
- www.medpharm.com
Supplier diversity
SAM.gov small-business designations
US small-business federal-contractor designation, self-certified in the U.S. federal System for Award Management (SAM.gov). Coverage is limited to matched U.S. small-business suppliers, so an absent designation is not evidence of its absence.
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