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Yale University - Mass Spectrometry and Proteomics Resource Core
Yale University - Mass Spectrometry and Proteomics Resource Core is listed as an academic core research supplier in the Scientist.com network, with 1 site in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Academic core
Protein Sciences
- Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
Where it operates
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
To address the broad range of complexity inherent in many proteomics projects, the Keck Laboratory offers a comprehensive array of instrumentation and services, and if necessary can develop complementary methods to achieve successful sample analysis. The methods generally follow two mainstream workflows. One workflow uses a gel based Quantitative or Differential 2D gel electrophoresis (DIGE) combined with tandem mass spectral identification of proteins, and another, uses an automated “bottom-up” or “shot-gun” tandem mass spectral peptide identification approach. Both of these approaches can...
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To address the broad range of complexity inherent in many proteomics projects, the Keck Laboratory offers a comprehensive array of instrumentation and services, and if necessary can develop complementary methods to achieve successful sample analysis. The methods generally follow two mainstream workflows. One workflow uses a gel based Quantitative or Differential 2D gel electrophoresis (DIGE) combined with tandem mass spectral identification of proteins, and another, uses an automated “bottom-up” or “shot-gun” tandem mass spectral peptide identification approach. Both of these approaches can be quantitative with chemical and stable-isotope tagging of proteins or peptides (e.g., ICAT, iTRAQ, SILAC). In addition, two new cutting edge MS based technology services involving phosphoproteome profiling, and absolute quantitative (“targeted”) proteomic analysis of multiple pre-selected biomarker proteins have been recently developed and being implemented.
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