- Supplier site
- Group of sites (click to zoom)
Scientist.com supplier network (site locations)
Research supplier
Axol Bioscience
Axol Bioscience is listed as a small business research supplier in the Scientist.com network, with 4 sites in 3 countries.
Sign in to Scientist.com to open this supplier in your organization's marketplace.
Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
- Cell Migration Assays Measure chemotaxis, haptotaxis, transmigration and wound-healing.
- Chemotaxis Assays Investigate the in vivo or in vitro movement of cells towards or away from a chemotactic agent.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Show all 7 in Biomarkers
- Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
Cell Culture and Characterization
- 3D Cell Culture Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
- Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
- Cell Culture Culture primary or immortalized cell lines.
- Cell Lines Purchase culture reagents, cell lines and cellular material of any species. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have...
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Gene-Edited iPSCs Disease Models Use gene-edited iPSCs to model human diseases.
Show all 13 in Cell Culture and Characterization
- Induced Pluripotent Stem (iPS) Cell Reprogramming Generate induced pluripotent stem cells from adult somatic cells.
- Isogenic Knockout iPSC Lines Mimic loss of function of genes associated with various diseases and disorders.
- Karyotyping Evaluate the number and appearance of chromosomes in the nucleus of a eukaryotic cell.
- Stem Cell Differentiation Acquire specialized cells from differentiated stem cells.
- Stem Cell Methodologies Study Stem Cell characteristics.
- STR Profiling - Microsatellite Short Tandem Repeat Confirm cell line identity and detect cross-contamination.
- Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.
Show all 61 services
Data Science/Bioinformatics
- Discovery Compound Screening Analytics Screening of an entire compound library directly against the drug target or in a more complex assay.
Disease Models
- Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
- Disease Simulation Modeling Disease Simulation Modeling
- Dry Eye Models Measure therapeutic endpoints such as tear induction, TBUT, Schirmer strips (tear volume) and cornea staining.
- Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
- Macular Degeneration Models Use a single animal species to create one or more models for eye disease.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
Show all 7 in Disease Models
- Pain Models Test therapeutic efficacy of drug candidate in pain model.
DNA & RNA
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
Human Biological Samples
- Biospecimen Finder Explore listings of Human Biological Samples from the suppliers on the scientist.com HBS database
- FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
- HBS Amyotrophic Lateral Sclerosis (ALS) For requesting HBS Amyotrophic Lateral Sclerosis (ALS).
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Adult Stem Cells Acquire human stem cells isolated from various adult tissues.
- Human iPSC's For requesting human sourced induced pluripotent stem cells.
Show all 8 in Human Biological Samples
- Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Apoptotic Cell Staining Detect apoptotic cells in culture.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell-based Screening Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
Show all 8 in In Vitro Assays
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Stem Cell Differentiation Microscopy Assay› Elucidate mechanisms of stem cell renewal and differentiation in vitro using fluorescence microscopy.
In Vitro Pharmacology
- In Vitro Cardiovascular Models Measure stimulation and inhibition of lipolysis, adipogenesis and endothelial cell migration.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Eye Models Measure cytokine production, cell viability, apoptosis and wound healing.
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
In Vitro Toxicology
- Cardiac Channels Measure the arrhythmia producing potential of test compounds.
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
- Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
- hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
- Microelectrode Array Cardiotoxicity Assays Use microelectrode array to measure cardiotoxicity-related activities.
Model Development
- Custom Model Development Develop a custom disease model.
Specialty Dosing Routes
- Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
Testing Services
- In Vitro Skin Models Measure skin model penetration and invasion, photosensitivity and toxicity.
- Safety In-Use Studies Safety-in-use studies assess the potential for a product to elicit adverse reactions under normal use conditions.
Other services
- iPSC-Derived Neural Stem Cells Use iPSC-derived neural stem cells as a CNS model to study neuronal behavior in development and neurodegeneration.
- New Request
Where it operates
Sites by country, with the cities in each.
-
United States 2 sites
-
France 1 site
-
United Kingdom 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Axol is a fresh and exciting biotech company founded to fulfil the unmet demand for high quality iPS cell-derived, clinically relevant cells for use in biomedical research and discovery. We are applying cutting-edge stem cell technologies to generate high quality human neural stem cells and neurons. Cerebral cortical neurons are implicated in numerous neurological diseases including Alzheimer’s, autism, epilepsy, traumatic brain injury and stroke. Despite growing support for research in these areas, high quality human in vitro cell models for cortical neurophysiology have been unavailable...
Show the full description
Axol is a fresh and exciting biotech company founded to fulfil the unmet demand for high quality iPS cell-derived, clinically relevant cells for use in biomedical research and discovery. We are applying cutting-edge stem cell technologies to generate high quality human neural stem cells and neurons. Cerebral cortical neurons are implicated in numerous neurological diseases including Alzheimer’s, autism, epilepsy, traumatic brain injury and stroke. Despite growing support for research in these areas, high quality human in vitro cell models for cortical neurophysiology have been unavailable until now. Axol has led the launch of their technology with a focus on providing both healthy and Alzheimer’s disease relevant human neurons derived from iPS cells.
We are providing researchers with an affordable, easily accessible, in vitro human system to complement their existing studies of cortical development, function and diseases, while helping them to avoid potential ethical challenges faced when considering the use of embryonic stem cells. Our technology provides a platform for developing or testing novel therapeutic interventions and understanding the disease pathologies more thoroughly.
Axol is headquartered and maintains production on the Babraham Research Campus, a bio-incubator renown for inspiring innovation and success, located in Cambridge, UK. We expect to see significant growth through milestone driven strategy and global diversification. As we expand, we will bring on a plethora of exceptional talent to help us further extend our manufacturing and marketing capabilities, including a diverse evolution of the product lines to ensure we become the leading global market authority for iPS Cell derived research components.
- Website
- www.axolbio.com
Work with Axol Bioscience on Scientist.com
For prices, more details, or to contact Axol Bioscience, visit Scientist.com.
Sign in to Scientist.com to open this supplier in your organization's marketplace.