Supplier site
Group of sites (click to zoom)

Scientist.com supplier network (site locations)

Research supplier

Southern Research Institute

Southern Research Institute is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country and 4 service areas.

View Southern Research Institute on Scientist.com

Email me this page as a PDF

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Logo Southern Research / Big Communications, via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.

Type of company: Mid sized business

Antibodies

SARS-CoV-2 (COVID-19) Antibodies Search for available SARS-COV-2 antibodies

Biomarkers

In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
Plaque Assays Determine infectious viral titer using plaque-forming units or purify viral stocks.

Cell Culture and Characterization

Bacterial Cell Culture Culture and Grow bacterial cells.
Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

Discovery Chemistry

Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
Natural Product Screening Screen large natural product collections for therapeutic activity.
Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.

Disease Models

Hepatitis B Virus Models Measure therapeutic endpoints in animal models of Hepatitis B virus infection.
Hepatitis C Virus Models Measure therapeutic endpoints in animal models of Hepatitis C virus infection.
Infectious Disease Models Test therapeutic efficacy of drug candidate in infectious disease model.
Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Influenza Models Measure therapeutic endpoints in animal models of influenza.
Malaria Models Measure therapeutic endpoints in animal models of malaria.

Show all 10 in Disease Models 4 more

Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
Pain Models Test therapeutic efficacy of drug candidate in pain model.
Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
Viral Infection Models Measure therapeutic endpoints in animal models of viral infection.

Show all 102 services 86 more

Drug Development

Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Small Molecule Drug Development Consulting Request consulting services related to small molecule development.

Effectiveness

Antimicrobial Pharmacodynamics Ascertain the effectiveness of an antimicrobial compound and test levels of antibiotic resistance against specific bacterial pathogens.
Bioequivalence Studies for Veterinary Drugs Assess the expected biological equivalence of two proprietary preparations of a veterinary drug.
In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
Laboratory Dose Confirmation Studies Conduct in vivo studies to confirm the effectiveness of a selected drug dose in the lab.

Food Safety & Regulations

Total Viable Count (TVC) Estimate the total living microbial populations present in a food or beverage sample to guarantee product quality.

General in vivo Toxicology

Carcinogenicity Study - Mouse Conduct a repeat dose, chronic carcinogenicity study in mice to determine the tendency of your compound to produce tumors.
Carcinogenicity Study - Rat Conduct a repeat dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
Dose Range Finding Study - Dog /Canine Conduct a study to determine the dose range of your compound in dogs/canines.
Dose Range Finding Study - Mouse Conduct a study to determine the dose range of your compound in mice.
Dose Range Finding Study - Rat Conduct a study to determine the dose range of your compound in rats.
General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

Show all 16 in General in vivo Toxicology 10 more

IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
Repeat Dose Toxicity Study - Dog / Canine Conduct a repeat dose study in dogs to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Monkey / Non-human Primate Conduct a repeat dose study in monkey/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Rat Conduct a repeat dose study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Dog / Canine Conduct a single dose study in Dogs and Canines to determine the toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Monkey / Non-human Primate Conduct a single dose study in Monkeys and Non-human Primates to determine the toxicokinetic behavior of your compound.
Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.

In Vitro Assays

Antivirals Measure anti-viral activity in biochemical and cell assays.
Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
HTS Assay Development Develop assays to use in high throughput screening.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
Microbiology Study microbes and their role in human health.

Show all 12 in In Vitro Assays 6 more

Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.
Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
Reporter Virus Particles (RVPs) - Dengue Neutralization Assay Use Dengue Reporter Virus Particles to measure neutralizing antibodies against each of the four Dengue serotypes.
SARS-CoV-2 (COVID-19) Assays Search for Available SARS-CoV-2 Assays
Viral Clearance Assays Measure the capacity to remove or inactivate infectious agents during the manufacturing process.
Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Pharmacology

Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
In Vitro Hypoxia Models Use in vitro models to measure therapeutic endpoints associated with hypoxia.

In Vivo ADME

Absorption studies Study the factors determning how efficiently a compound may enter the bloodstream.
In Vivo Radiolabeled Metabolism Determine the qualitative and quantitative metabolism and/or degradation of an active ingredient in animals.
Quantitative Whole Body Autoradiography (QWBA) Determine the tissue distribution of a radiolabeled compound in Rodent and Non-Rodent Species.
Quantitative Whole Body Autoradiography (QWBA) - Rodent Species (Mouse, Rat) Conduct a study to determine the tissue distribution of your compound radiolabeled compound in rodent species.
Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.

In Vivo Pharmacokinetics

In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
Mouse Efficacy Monotherapy Use mouse models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Pharmacokinetic (PK) Screening Measure the absorption, distribution, metabolism and excretion of a compound.
Pharmacokinetic (PK) Screening - Dog / Canine Run pharmacokinetic studies in dogs that measure a drug’s absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Monkey / Non-human Primate Conduct a pharmacokinetic screening study in monkeys/non-human primates that measures the absorption, distribution, metabolism and excretion of your compound.

Show all 13 in In Vivo Pharmacokinetics 7 more

Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Rat Efficacy Combination Use rat models to determine the anti-cancer efficacy and potential synergy of a drug candidate with a standard drug treatment.
Rat Efficacy Monotherapy Use rat models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.
Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Model Development

Non-Human Primate Models Use a single animal species to create one or more disease models.
Transgenic Models Create animal models engineered for use in a specific therapeutic area.

Oncology Models

Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.

Other Specialty Toxicology

Viral Testing Characterize viral products for functional activity and possible contamination.

Protein Sciences

Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
Protein Binding Determine drug-protein binding interactions

REACH Services

OECD 421: Reproduction/Developmental Toxicity Screening Test The test substance is administered in graduated doses to several groups of males and females.
OECD 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance.

Safety Pharmacology

Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.

Specialty Dosing Routes

Dermal Toxicology Assess toxicity in rodent dermal testing models.
Intravitreal Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intravitreal ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intravenous Infusion Study - Dog / Canine Conduct a repeat dose intravenous infusion study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intravenous Infusion Study - Monkey / Non-human Primate Conduct a repeat dose intravenous infusion study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intravenous Infusion Study - Rats Conduct a repeat dose intravenous infusion study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Single Dose Acute Intravenous Infusion Study - Dog / Canine Conduct a single dose intravenous infusion study in dogs/canines to determine the toxicokinetic behavior of your compound.

Show all 14 in Specialty Dosing Routes 8 more

Single Dose Acute Intravenous Infusion Study - Monkey / Non-human Primate Conduct a single dose intravenous infusion study in monkeys/non-human primates to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intravenous Infusion Study - Other Species Conduct a single dose intravenous infusion study in other species to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intravenous Infusion Study - Rats Conduct a single dose intravenous infusion study in rats to determine the toxicokinetic behavior of your compound.
Topical Dermal Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to dogs/canines.
Topical Dermal Toxicity and/or Toxicokinetic Study - Monkeys/Non-human Primates Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to monkeys/non-human primates.
Topical Dermal Toxicity and/or Toxicokinetic Study - Mouse Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to mice.
Topical Dermal Toxicity and/or Toxicokinetic Study - Rabbit Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rabbits.
Topical Dermal Toxicity and/or Toxicokinetic Study - Rat Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rats.

Testing Services

In Vitro Toxicology Testing Non-animal testing employing US and international methodologies for determining irritation and other undesirable potentials.

Other services

New Request

Service areas:

Biology DMPK Pharmacology Toxicology

United States Birmingham 2 sites

Southern Research Institute offers pathology, veterinary services, metabolism studies, tumor xenograft models, immunogenicity studies, and genetic services.

Professional associations: ACS, BioAlabama
Website: www.southernresearch.org

Work with Southern Research Institute on Scientist.com

For prices, more details, or to contact Southern Research Institute, visit Scientist.com.

View on Scientist.com