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Research supplier
Neuro-Zone
Neuro-Zone is listed as a small business research supplier in the Scientist.com network, with 3 sites in 1 country and 4 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Antibodies
- Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
Biomarkers
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
- Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
Cell Culture and Characterization
- Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
DNA & RNA
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
- Targeted Sequencing/Resequencing Detect variations in a genome subset.
Show all 44 services
In Vitro ADME
- Cell Fractionation Isolate organelles and subcellular components.
In Vitro Assays
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Assay Development Construct or create new assays or modify existing ones.
- Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
Show all 13 in In Vitro Assays
- Cell Proliferation Measure cell number, cell viability and cell division.
- High Content Screening Analyze whole cells or components of cells with simultaneous readout of several parameters.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
- Inflammation Assays Identify and validate pro- and anti-inflammatory molecules, recruitment inhibitors and chemotaxis modulators.
- Oxidative Burst Examine the release of reactive oxygen species (ROS) from neutrophils and other immune cells.
- Phenotype Assays Measure effects of drug candidate on the morphology or function of cells and whole animals.
- Reactive Species Assays Use biochemical, cell-based or in vivo assays to detect and evaluate the effects of reactive species.
In Vitro Pharmacology
- Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
- Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
- Immuno-oncology Assays Use biochemical, cell based or in vivo assays to measure the activity of immuno-therapy targets.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
Show all 10 in In Vitro Pharmacology
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
- Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
- Target Identification Identify the target(s) of a biologically active substance.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
- Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
Product Orders
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Protein Sciences
- Cytokines Find recombinant cytokines or cytokine assays.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
Other services
- In Vitro Neurodegenerative Disease Platform Use an IVND platform to screen different compounds/drugs in a finely controlled synaptopathies scenario.
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
Italy 3 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Neuro-Zone s.r.l. mission is to support drug discovery programs by providing well controlled physiologically relevant primary cell models and a multiparametric cell-based assay platform in order to increase efficiency of lead optimization projects. By combining over 15 years of basic research expertise in culturing physiologically relevant cell systems with innovative approaches in the fields of microengineering, microfluidics and advanced biocompatible materials, Neuro-Zone srl aims at becoming the reference company for both customized assistance to primary cell culturing activities...
Show the full description
Neuro-Zone s.r.l. mission is to support drug discovery programs by providing well controlled physiologically relevant primary cell models and a multiparametric cell-based assay platform in order to increase efficiency of lead optimization projects.
By combining over 15 years of basic research expertise in culturing physiologically relevant cell systems with innovative approaches in the fields of microengineering, microfluidics and advanced biocompatible materials, Neuro-Zone srl aims at becoming the reference company for both customized assistance to primary cell culturing activities and high profile lead optimization screening services.
Neuro-Zone s.r.l is the 2008 Winner of the Most Innovative and Creative Company in the Province of Milano and was ranked among the top 25 Most Innovative European Life Science SMEs at the 2009 Eurecan Venture Summit.
- Website
- www.neuro-zone.com
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