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Research supplier
TRN - The Research Network Ltd.
TRN - The Research Network Ltd. is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
Clinical Consulting
- Bioanalysis Consulting Expert advice to properly and effectively discover, evaluate, and measure chemical or biological materials.
- Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.
- Cell Services Consulting Whether you are an experienced drug hunter working in the pharmaceutical industry or an academic researcher looking to submit g...
Data Science/Bioinformatics
- In Silico ADME-PK Consultation Consult with experts for ADME-PK data analysis or predictive modelling design in different in vivo or in vitro states.
- In Silico ADME-PK Predictions Use computer software to simulate in vivo physiological conditions of animals or humans to predict ADME-PK properties.
Discovery Chemistry
- Activity Prediction Identify possible chemical hits based on the known three-dimensional structure of a protein.
- Compound Docking Identify potential compound hits based on the 3D structure of a target protein.
- Compound Purchase Consulting Buy compounds, building blocks or compound libraries.
- Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
- Discovery Computational Chemistry Model the interaction of a drug candidate with protein targets such as kinases, GPCRs, receptors, ion channels or enzymes.
- Library Design & Evaluation Use structural knowledge to design target-focused compound libraries for screening.
Show all 10 in Discovery Chemistry
- Pharmacophore Modeling Use computer models to identify hits based on structural similarity to known active compounds.
- QSAR Analysis Develop quantitative structure–activity relationship models for drug design.
- Structure Activity Relationship (SAR) Analyze the relationship between the structure of a compound and its biological activity.
- Virtual Screening Use software algorithms to virtually screen millions of potential compounds and peptides for binding.
Show all 52 services
Disease Models
- Acne Models Measure therapeutic endpoints in animal models of acne.
- Acute Kidney Failure Models Measure therapeutic endpoints in animal models of acute kidney failure.
- Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
- Hematopoiesis Models Measure therapeutic endpoints in animal models of hematopoiesis.
- Pain Model Consulting Expert advice to better evaluate and understand pain thresholds and phenomena within living organisms. Can be used to evaluate pain associated with specific diseases or injuries affecting the sensory and nervous systems.
DNA & RNA
- NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
- RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
- Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
- Consulting Services Work with consultants who provide expert advice in various areas of research and technology.
- Medicinal Chemistry Consulting Apply chemistry training to the process of synthesizing new pharmaceuticals.
- Pathophysiology Consulting Request services related to Pathophysiology Consulting
- Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.
Show all 9 in Drug Development
- Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.
- Structural Chemistry Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
- Toxicology Consulting Use models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
In Vitro Assays
- Cell Based Assays Consulting Expert advice to evaluate the functions of specific chemicals based on their constructions and systems.
In Vitro Pharmacology
- Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
- Protease Assay Measure protease activity in biochemical and cell-based assays.
In Vitro Toxicology
- ADCC and CDC Assay Services Measure toxicity of antibodies.
- Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
- Cardiotoxicity Consulting Evaluate cardiotoxicity via drug-drug interactions.
- Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
In Vivo Pharmacokinetics
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
Model Development
- Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
- Juvenile Toxicology Assess developmental and reproductive defects due to neurobehavioral, skeletal and muscle growth effects.
- Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Other Specialty Toxicology
- Biosafety Testing Consulting Expert advice to conduct safe and responsible biological procedures and practices.
Protein Sciences
- Protein Engineering Alter the features or properties of a protein for a specific purpose.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
Regulatory Consulting
- Environmental Fate and Ecotoxicology Data Review Identify relevant endpoints for fate and behavior (metabolism and excretion, degradation and soil adsorption) and toxicity (soil organisms, aquatic organisms, and dung fauna) of animal health products.
- Environmental Risk Assessment Conduct EU and US Environmental Assessment (ERA/EA) phases one and two according to VICH guidelines.
- Toxicology Data Review Identify relevant toxicological endpoints for “No Observed (Adverse) Effect Level” (NO(A)EL) or “Lowest Observed (Adverse) Effect Level” (LO(A)EL).
Safety Pharmacology
- Abuse Liability Determine the dependence potential of a therapeutic.
Service areas:
Where it operates
Sites by country, with the cities in each.
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United Kingdom 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
The Research Network (TRN) is dedicated to making life easier and more productive for those involved in outsourcing TRN provides practical guidance and assistance to help you rapidly search and identify service providers to meet your needs and if required can oversee effectively delivery of that work form bespoke reagents/compounds/screens to fully integrated project management. Our experienced team has in depth expertise in Medicinal Chemistry, Biology, ADME, Safety Pharmaciology, Toxicology, Pharmaceutical Science, CMC and API with extensive outsourcing experience. TRN provides a complete...
Show the full description
The Research Network (TRN) is dedicated to making life easier and more productive for those involved in outsourcing
TRN provides practical guidance and assistance to help you rapidly search and identify service providers to meet your needs and if required can oversee effectively delivery of that work form bespoke reagents/compounds/screens to fully integrated project management. Our experienced team has in depth expertise in Medicinal Chemistry, Biology, ADME, Safety Pharmaciology, Toxicology, Pharmaceutical Science, CMC and API with extensive outsourcing experience.
TRN provides a complete package of expertise and IT solutions to ensure that their client’s outsourced projects deliver on time and on budget. These services include developing workplans for contract, price negotiating, supporting the science, materials and data logistics including customs and other licence applications and vendor relationship management.
TRN works on behalf of its clients and accepts no commission from CRO to ensure that its advice is completely independent and impartial. Integrity and delivery are our core values and we strive to achieve customer delight. Please visit our website for a full list of services.
- Website
- www.trn.net
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