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Research supplier
Gentronix
Gentronix is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
General in vivo Toxicology
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
In Vitro Assays
- Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
In Vitro Toxicology
- Genotoxicity Evaluate potential of a compound to cause mutations and chromosomal aberations
REACH Services
- In Vitro REACH Services Perform skin or eye irriation tests, sensitivily and geneotoxicity tests
- OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...
- OECD 432: In Vitro 3T3 NRU Phototoxicity Test Test the cytotoxic effects of chemical substances and environmental samples on cell membranes.
- OECD 437: Bovine Corneal Opacity and Permeability Test Method (BCOP) for Identifying Ocular Corrosives and Severe Irritants The Bovine Corneal Opacity and Permeability test method (BCOP) is an in vitro test method that can be used to classify substances as 'ocular corrosives and severe irritants'.
- OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
- OECD 473: In Vitro Mammalian Chromosomal Aberration Test Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
Show all 10 in REACH Services
- OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
- OECD 476: In Vitro Mammalian Cell Gene Mutation Test (Mouse Lymphoma Assay) Determine if a compound is mutagenic by using cultured mammalian cells.
- OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Testing Services
- Bacterial Reverse Mutation Assay Test whether a cosmetic product or ingredient causes DNA mutations in bacteria.
- OECD 439: Skin Irritation Test (SIT) Reconstructed Human Epidermis Test (RhE) Method - An in vitro testing method designed to identify chemicals and/or mixtures capable of inducing moderate skin irritation.
- OECD 442C: Direct Peptide Reactivity Assay (DPRA) Determine whether a test article satisfies the protein-binding criterion for skin sensitizers.
- OECD 442D: ARE-Nrf2 Luciferase Test An in vitro test method (KeratinoSensTM and/or LuSens) that models the second key event in the Adverse Outcome Pathway for Dermal Sensitization.
- OECD 442E: Human Cell Line Activation Test (h-CLAT) In vitro skin sensitization test to predict skin sensitization potency.
Show all 19 services
Other services
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Service areas:
Where it operates
Sites by country, with the cities in each.
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United Kingdom 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Gentronix offers toxicology, genotoxicity assays, and predictive toxicology. Gentronix is a well established biotechnology innovation and service company specialising in early screening for genotoxicity for a range of industries including; pharmaceuticals, chemicals, agrochemicals, personal care, consumer products, flavours, fragrances and taste enhancers, and medical devices. In addition to classical genotoxicity assays, Gentronix has developed BlueScreen™HC and GreenScreen®HC which are novel, patented systems that unlike earlier assays, detect all known classes of genotoxin. In addition...
Show the full description
Gentronix offers toxicology, genotoxicity assays, and predictive toxicology. Gentronix is a well established biotechnology innovation and service company specialising in early screening for genotoxicity for a range of industries including; pharmaceuticals, chemicals, agrochemicals, personal care, consumer products, flavours, fragrances and taste enhancers, and medical devices.
In addition to classical genotoxicity assays, Gentronix has developed BlueScreen™HC and GreenScreen®HC which are novel, patented systems that unlike earlier assays, detect all known classes of genotoxin.
In addition to early screening, Gentronix provides assays and advice on follow-up strategies for positive results and mechanism elucidation to help chemists modify compounds to eliminate genotoxicity early in product discovery and development thereby preventing late stage failure.
- Website
- gentronix.co.uk
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