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Research supplier
Research Institute for Liver Diseases (Shanghai) Co., Ltd.
Research Institute for Liver Diseases (Shanghai) Co., Ltd. is listed as a new startup research supplier in the Scientist.com network, with 1 site in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: New startup
Chemical and Compound Analysis
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
Human Biological Samples
- Human Cell Lysates For requesting human Cell lysates.
- Human Plasma Acquire fresh/frozen human plasma
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
In Vitro ADME
- Caco-2 Cell Permeability Measure passive diffusion of drugs across Caco2 cell monolayers.
- Cell Permeability and Absorbance Models Cell Permeability and Absorbance Model assay.
- CYP Induction Detect increases in the expression of various isoforms of cytochrome P450 (CYP450).
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
- Drug Distribution Studies Determine the metabolic fate of compounds within tissues, organs and plasma.
Show all 11 in In Vitro ADME
- Membrane Transporters Use Caco 2 cells to assess bi-directional drug transport in the presence or absence of P-glycoprotein (P-gp) inhibitors.
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
- Metabolic Stability in Hepatocytes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver cells.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
Where it operates
Sites by country, with the cities in each.
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China 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Company Name：Research Institute for Liver Diseases (Shanghai) Co., Ltd Company type：Foreign ownership (Established by oversea student returnees) Biomedical research facilities and equipments in Shanghai Zhangjiang Hi-Tech Park covers an area 560 square meters for in vitro drug metabolism and interaction of services facilities including chemical analysis laboratory, Laboratory of Biochemistry, cell culture room, class II Pathogen Biology Laboratory fully equipped with critical apparatus and equipments such as cell incubator, high performance liquid chromatograph, ultra-low temperature...
Show the full description
Company Name：Research Institute for Liver Diseases (Shanghai) Co., Ltd
Company type：Foreign ownership (Established by oversea student returnees)
Biomedical research facilities and equipments in Shanghai Zhangjiang Hi-Tech Park covers an area 560 square meters for in vitro drug metabolism and interaction of services facilities including chemical analysis laboratory, Laboratory of Biochemistry, cell culture room, class II Pathogen Biology Laboratory fully equipped with critical apparatus and equipments such as cell incubator, high performance liquid chromatograph, ultra-low temperature refrigerators, ultra low temperature process refrigeration equipment and LCMSMS.
Equipped with high quality research equipments and well-trained scientists, RILD provides world-class CRO services in in vitroADME services. RILD is the most leading in vitro ADME service provider in China.
- Website
- www.rild-biotech.com
Work with Research Institute for Liver Diseases (Shanghai) Co., Ltd. on Scientist.com
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