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Xentech
Xentech is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Bioimaging
- Bioimaging Visualize biological process non-invasively in real time.
Biomarkers
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
- Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
- Colony Forming Cell Assay Examine ability of hematopoietic stem cells to form colonies in vitro.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Cell Culture and Characterization
- Explant Culture Culture cells obtained from a part or parts of an in vivo structure.
- In Vitro Hydrogel-Based Culture of PDXs Enable the extended laboratory culture of cancer PDXs and other primary cells in 3D.
Disease Models
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
Effectiveness
- In Vitro Dose Determination Tests Determine the most appropriate effective drug dosage regimen(s) in vitro.
General in vivo Toxicology
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
- Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Show all 47 services
Human Biological Samples
- Custom PDX models For requesting Custom PDX models
- Existing PDX models For requesting Existing PDX models
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
In Vitro Assays
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.
In Vitro Pharmacology
- Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
- In Vitro Oncology Models Use cell-based and biochemical models of cancer.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
- Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
In Vivo Pharmacokinetics
- In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
- Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Model Development
- Disease Model Database For sourcing disease models.
- PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
- SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
- SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.
Oncology Models
- Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
- Cachexia Models Measure therapeutic endpoints in animal models of cachexia.
- Digestive System PDX Patient derived xenografts relating to organs and components of the digestive system. This includes, but is not limited to the Stomach, Intestines, Liver, Colon, Colorectal samples and Gastric samples.
- Endocrine System PDX Patient derived xenografts related to the endocrine system. PDX related to glands controlling hormone regulation such as the Pituitary glands, Thyroid Glands, Adrenals, and Pancreas.
- Immuno-PDX Utilize the patient-derived xenograft for drug response profiling and biomarker discovery of immuno-oncology drug candidates.
- Liver PDX Measure therapeutic endpoints in patient-derived xenografts of liver cancer.
Show all 15 in Oncology Models
- Nervous System PDX Patient derived xenografts relating to the components of the Nervous System. This includes PDX from the Brain, Spinal Cord, and Nerves.
- Oncology Derived PDX Patient derived xenografts derived from various oncological samples. This includes, but is not limited to, samples from Lymphoma, Melanoma, and Leukemia.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
- Oncology Xenografts Xenografts derived from oncological samples.
- Ovarian Cancer Mouse Measure therapeutic endpoints in animal models of ovarian cancer.
- Renal Xenograft Measure therapeutic endpoints in renal models of cancer.
- Reproductive System PDX Patient derived xenografts relating to reproductive systems. This includes PDX from reproductive organs such as the Ovaries, Cervix, Breasts, Testes, Prostate, and Scrotum.
- Urinary System PDX Patient Derived Xenografts relating to organs that comprise the Urinary system. This includes, but is not limited to, samples from the Kidneys, Liver, and Bladder.
- Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.
Scientific Data Services
- Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.
Other services
- Apcmin/+ Mouse Use a single animal species to create one or more disease models for cachexia.
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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France 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
XenTech provides contract research services for the preclinical evaluation of cancer drug efficacy in patient-derived tumor xenografts (PDX). Our team delivers a high quality, flexible and tailored approach to all research objectives in preclinical oncology, whether a one-off service or a complete research program. The range of services provided by Xentech includes: dose finding PK/PD lead identification and drug response biomarker identification. A unique PDX collection In vivo and in vitro assays are performed on tumor PDX models. XenTech's collection includes breast cancer (the world’s...
Show the full description
XenTech provides contract research services for the preclinical evaluation of cancer drug efficacy in patient-derived tumor xenografts (PDX). Our team delivers a high quality, flexible and tailored approach to all research objectives in preclinical oncology, whether a one-off service or a complete research program.
The range of services provided by Xentech includes:
- dose finding
- PK/PD
- lead identification
- and drug response biomarker identification.
A unique PDX collection
In vivo and in vitro assays are performed on tumor PDX models. XenTech's collection includes breast cancer (the world’s largest panel of breast cancer PDX), lung cancer (NSCLC and SCLC), colon cancer, prostate cancer, kidney cancer, ovarian cancer, pancreas cancer, melanoma, liposarcoma, glioma and liver pediatric tumors.
Highly characterized PDXs
We put a lot of effort into PDX characterization such as high-content molecular databases (gene expression, CNV, sequence checked mutations) and drug response profiles.
- Website
- www.xentech.eu
Work with Xentech on Scientist.com
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