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Smithers

Smithers is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country and 1 service area.

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Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Agricultural Sciences Compliance and Quality Control Measures

  • Juvenile Growth Test Examine the adverse effects of recurrent and long-term toxin exposure on juvenile fish development.
  • OECD 104: GLP Vapour Pressure Measure the vapor pressure of a test substance.
  • OECD 106: Adsorption Study Estimate the adsorption/desorption behavior of a chemical on different soil types.
  • OECD 213: Honey Bee Acute Oral Toxicity Test Expose adult bees to a test chemical by feeding over 2 days for short-term toxicity assessment.
  • OECD 214: Honey Bee Acute Contact Toxicity Test Expose adult bees to a test chemical by topical application over 2 days for short-term toxicity assessment.
  • Sediment-Water Toxicity Test Isolate the water of a sediment-based habitat to analyze the properties for toxicity evaluation.
Show all 9 in Agricultural Sciences Compliance and Quality Control Measures 3 more
  • Seed Germination Test Assess the potential of live seeds to develop into normal seedlings under conducive conditions.
  • Seed Vigor Test Use a range of tests to monitor seed capacity for plant growth under sub-optimal conditions.
  • Spray Drift Testing requirements for the movement of product through air.

Agricultural Sciences Research & Development

  • Agro-product Storage Stability Testing Monitor agro-product changes over time to optimize packaging, storage conditions and product longevity.
  • Agrochemical Analytical Method Development Engineer sensitive and selective methods that meet GLP validation requirements to assess different agrochemical properties.
  • Agrochemical Physio-Chemical Testing Conduct extensive property characterization of agrochemicals for geo-specific product approval and registration.

Chemical and Compound Analysis

  • Adsorption/Desorption Studies Obtain data on groundwater risk assessment.
  • API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
  • Chemical Stability Measure the stability of small molecules in solution.
  • Chiral Separation Purify therapeutically active isomers of drug candidates.
  • Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
  • Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
Show all 13 in Chemical and Compound Analysis 7 more
  • High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
  • Liquid Chromatography Separate substances using a mobile and stationary phase.
  • MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
  • Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
  • Partition Coefficient Determine lipophilicity (hydrophobicity) of compounds by measuring log P.
  • Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
  • UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.
Show all 63 services 48 more

Chemistry, Manufacturing and Controls (CMC)

  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Forced Degradation Run light, heat, humidity, acid hydrolysis and oxidation tests to evaluate substance degradation.
  • Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.
  • Thermo Scientific iCAP Q ICP-MS Expand your analytical capabilities with this complete trace elemental analysis solution for your high-throughput lab.

Developmental and Reproductive Toxicology (DART)

  • Early-Life Stage Toxicity Test Use survival and growth metrics of embryos or larvae to predict effects or find maximum acceptable value of a toxin.

Discovery Chemistry

  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
  • Leaching and Aged Leaching Assess the leaching potential of products with studies that follow the formation and movement of metabolites or show restricted leaching under simulated use conditions.

Environmental Assessment

  • Aquatic Effects Studies Assess the impact of human and veterinary drugs on aquatic ecosystems and animals, like fish and zooplankton (Daphnia).
  • Environment Fate Studies Evaluate the behavior of veterinary drugs and additives under controlled field and lab conditions.
  • Hydrolysis Studies Meet international regulatory guidelines with fully compliant hydrolysis testing.
  • Soil Dissipation Studies Find out how products degrade and dissipate in soil under typical use conditions.
  • Terrestrial Effects Studies Assess the exposure and adverse effects of veterinary antibiotics to terrestrial ecosystems.
  • Veterinary Environmental Assessment Assess whether environmental impacts may occur from the manufacture, use, or disposal of veterinary drugs.

Farm & Livestock Solutions

  • OECD 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC) This Test Guideline describes an experimental method using HPLC for the estimation of the adsorption coefficient Koc in soil and in sewage sludge.
  • Soil Acidity Testing Determine soil acididty to assess plant suitability or amend soil pH.
  • Soil Alkalinity Testing Determine soil alkalinity to assess plant suitability or amend soil pH.
  • Soil Environmental Testing Measure environmental contaminants using soil sample analysis.
  • Soil Fumigation Services Apply precise soil treatments to reduce soil-borne pests and maximize crop yield.
  • Soil Organic Matter Testing Evaluate soil organic matter to enable long-term soil health and optimal crop yield.
Show all 7 in Farm & Livestock Solutions 1 more
  • Soil Testing Use various tests to characterize a soil sample.

General in vivo Toxicology

  • Avian Toxicology Investigation Use toxicity tests to predict avian exposure risk, assess exposure effects or confirm product safety for registration.
  • Short-Term Toxicity Tests Acquire preliminary data about the concentrations, exposure duration and effects of a toxin on organisms.

In Vitro Toxicology

  • Cytotoxicity Test for effects on cell viability and proliferation

In Vivo ADME

  • In Vivo Radiolabeled Metabolism Determine the qualitative and quantitative metabolism and/or degradation of an active ingredient in animals.

Other Specialty Toxicology

  • Hypoaspis Toxicity Tests Use Hypoaspis mortality to measure the short-term impact of a single or multiple exposure(s) to a test chemical.
  • Larval Honey Bee Toxicity Test (Repeated Exposure) Use repeated agrochemical feeding exposures measured at defined intervals to assess fatality in larval honey bees.
  • Larval Honey Bee Toxicity Test (Single Exposure) Use a single agrochemical feeding exposure to determine lethality or sub-lethal toxicity in larval honey bees.
  • Semi-Static Acute Toxicity Test Measure toxicity endpoints in aquatic organisms exposed to renewed test solutions at defined intervals of an experiment.
  • Static Acute Toxicity Test Measure toxicity endpoints in aquatic organisms exposed to a non-renewed test solution for the entire experiment.

REACH Services

  • OECD 209: Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation) This Test Guideline is designed to assess the effects of a substance on micro-organisms from activated sludge of waste-water treatment plants by measuring their respiration rate (carbon and/or ammonium oxidation) as...
  • OECD 417: Toxicokinetics Study Obtain data on absorption, distribution, metabolism, and elimination of test substances.
  • OECD 452: Chronic Toxicity Studies Evaluate the direct and indirect impact of prolonged and repeated toxin exposure to test organisms.

Regulatory Consulting

  • Environmental Fate and Ecotoxicology Data Review Identify relevant endpoints for fate and behavior (metabolism and excretion, degradation and soil adsorption) and toxicity (soil organisms, aquatic organisms, and dung fauna) of animal health products.
  • Environmental Risk Assessment Conduct EU and US Environmental Assessment (ERA/EA) phases one and two according to VICH guidelines.

Target Animal and Human Food Safety

  • Honey Bee Chronic Feeding Test Evaluate the toxic effects of an agrochemical after 10 days of feeding exposure in adult honey bees.

Testing Services

  • Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
  • Elevated Temperature Stability Determine the stability of a product at elevated temperature.
  • Real-time Stability Test Assure stability and physical integrity of consumer products in real-time conditions.

Service areas:

Toxicology

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United Kingdom Harrogate 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Smithers Viscient offers in vitro toxicology testing, ecotoxicology testing, and in vivo toxicology testing services.

Website
www.smithers.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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