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National BioService
National BioService is listed as a small business research supplier in the Scientist.com network, with 3 sites in 2 countries.
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Sites
3
Countries
2
Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Small business
Biomarkers
- Customized Primary Cell Isolation Plan and execute the isolation of primary cells from a specific biosample.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
- Human Primary Cell Isolation Isolate primary cells from various human tissues.
- Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Show all 9 in Biomarkers
- Multi-Omics Study Use an integrated multi-omics study to understand a disease mechanism.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
Cell Culture and Characterization
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
Chemical and Compound Analysis
- Centrifugal Precipitation Chromatography Separate analytes based on their solubility in ammonium sulfate solution.
- Chiral Separation Purify therapeutically active isomers of drug candidates.
- Denaturing High Performance Liquid Chromatography Separate mixtures of denatured and reannealed oligos to identify single nucleotide substitutions, deletions and insertions.
- Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
Show all 18 in Chemical and Compound Analysis
- Headspace Gas Chromatography Analyze volatile organic compounds (VOCs) partitioned above the liquid/solid phase of a sample.
- Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
- Ion Exchange Chromatography Separate and detect analytes.
- Liquid Chromatography Separate substances using a mobile and stationary phase.
- MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Protein Binding HPLC Uses high pressure liquid chromatography to separate protein-drug complexes.
- Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
- Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
Show all 142 services
Chemical and Compound Testing
- Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- In Silico Epigenetic Compound Library Screening Use computer-aided methods to discover new compounds against key regulators of epigenetic signaling.
Developmental and Reproductive Toxicology (DART)
- Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.
Discovery Chemistry
- LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Disease Models
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
- Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
- Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
- Dry Eye Models Measure therapeutic endpoints such as tear induction, TBUT, Schirmer strips (tear volume) and cornea staining.
Show all 10 in Disease Models
- General Pain Models Measure therapeutic endpoints in animal models of general pain.
- Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Pain Models Test therapeutic efficacy of drug candidate in pain model.
DNA & RNA
- Amplified Fragment Length Polymorphism Detection Detect DNA polymorphisms based upon restriction enzyme digestion and PCR.
- Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
- Cell Free DNA Assay Detect known mutations and discover new ones in cell-free plasma DNA.
- ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
- De Novo Genome Sequencing Determine the DNA sequence of uncharacterized genomes.
- DNA Hydroxy Methylation Seq Use epigenetic services to analyze genome-wide DNA hydroxymethylation.
Show all 16 in DNA & RNA
- Exome Sequencing Determine protein-coding nucleotide sequences in a DNA sample.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- Genotyping Examine a DNA sequence to identify specific genetic varients .
- Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
- Restriction Fragment Length Polymorphism Identification Uses gel electrophoresis to identify differences in restriction fragment lengths produced by enzymatic digestion of DNA.
- SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
- Targeted Sequencing/Resequencing Detect variations in a genome subset.
- Whole Genome Bisulphite Seq Profile genome-wide DNA methylation.
- Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.
- Whole Genome Sequencing Determine the entire genetic make-up of an organism.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
Human Biological Samples
- BronchoAlveolar Lavage (BAL) Acquire fresh/frozen normal bronchial lavage based on patient demographics and history.
- HBS Alzheimer's Acquire fresh, frozen, or fixed Alzheimer's tissues or other related Alzheimer's HBS.
- HBS Amyotrophic Lateral Sclerosis (ALS) For requesting HBS Amyotrophic Lateral Sclerosis (ALS).
- HBS Asthma For requesting HBS Asthma.
- HBS Chronic Obstructive Pulmonary Disease (COPD) Acquire fresh, frozen, or fixed COPD tissue or for requesting other COPD human biospecimen samples.
- HBS Diabetes For requesting HBS Diabetes.
Show all 55 in Human Biological Samples
- HBS Healthy/Controls For requesting HBS Healthy/Controls
- HBS Huntington's For requesting HBS Huntington's.
- HBS Leukemia For requesting HBS Leukemia
- HBS NASH For requesting HBS NASH
- HBS NSCLC For requesting HBS NSCLC
- HBS Oncology For requesting Human biospecimens from Oncology indications
- HBS Parkinson's For requesting HBS Parkinson's
- HBS: Human Biological Samples Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- HBS: Human Biological Samples - VMS Request human biosamples including tissues, blood, serum, bone marrow, tissue microarrays, etc.
- Human Amniotic Fluid Acquire fresh/frozen normal amniotic fluid based on patient demographics and history.
- Human Ascites Acquire fresh/frozen Ascites based on patient demographics, disease stage, treatment and history.
- Human Biofluids Acquire fresh/frozen biofluids based on patient demographics, disease stage, history and treatment.
- Human Blood Acquire fresh/frozen human blood based on patient demographics, disease stage, history and treatment.
- Human Blood by-products For requesting Human Blood By-products
- Human Bone Marrow Aspirates Acquire fresh/frozen Bone Marrow mononuclear cells based on patient demographics, disease stage, treatment and history.
- Human Bone Marrow Cells Acquire fresh, frozen, or fixed normal bone marrow based on patient demographics and history.
- Human Breast Milk Acquire fresh/frozen normal breast milk based on patient demographics and history.
- Human Buffy Coats Acquire fresh/frozen Buffy Coats based on patient demographics, disease stage, treatment and history.
- Human Cell Lysates For requesting human Cell lysates.
- Human Cell Products For requesting human cell by products like proteins, lysates, lysosomes etc
- Human Cerebral Spinal Fluid (CSF) Acquire fresh/frozen normal cerebrospinal fluid based on patient demographics and history.
- Human DNA Acquire human DNA.
- Human DNA & RNA Acquire fresh/frozen Human DNA & RNA based on patient demographics, disease stage, treatment and history
- Human Fecal Matter Acquire fresh/frozen normal feces based on patient demographics and history.
- Human Fixed Tissue Acquire Human fixed tissue based on patient demographics, disease stage, history and treatment.
- Human Fresh Tissue For requesting fresh human tissue
- Human Frozen Tissue For requesting frozen human tissue.
- Human Immortalized Cell Culture For requesting human cells Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that...
- Human Leukopaks Obtain enriched leukapheresis-derived products from normal peripheral blood.
- Human Microglia Acquire human microglia isolated from brain tissue.
- Human Nasal Fluid Acquire fresh/frozen normal nasal fluid based on patient demographics and history.
- Human Peripheral Blood Mononuclear Cells (PBMCs) Acquire fresh/frozen normal PBMCs based on patient demographics and history.
- Human Plasma Acquire fresh/frozen human plasma
- Human Primary Cells Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely”...
- Human RNA Acquire fresh/frozen Human RNA based on patient demographics, disease stage, treatment and history.
- Human Saliva Acquire fresh/frozen normal saliva based on patient demographics and history.
- Human Semen Acquire fresh/frozen normal semen based on patient demographics and history.
- Human Serum Acquire fresh/frozen normal serum based on patient demographics and history.
- Human Sputum Acquire fresh/frozen normal sputum based on patient demographics and history.
- Human Synovial Fluid Acquire fresh/frozen normal synovial fluid based on patient demographics and history.
- Human Tears Acquire fresh/frozen Tears based on patient demographics, disease stage, treatment and history.
- Human TMA For requesting Human Tissue MicroArrays
- Human Urine Acquire fresh/frozen normal urine based on patient demographics and history.
- Human Vaginal Fluid/ Swab Acquire fresh/frozen normal vaginal fluid based on patient demographics and history.
- Human Vitreous Humor Acquire fresh/frozen normal vitreous humor based on patient demographics and history.
- Human Whole Blood For requesting Human Whole Blood
- Non-Hodgkin's Lymphoma Human Mononuclear Cells Acquire fresh/frozen Non-Hodgkin's Lymphoma mononuclear cells based on patient demographics, disease stage, treatment and history.
- Ovarian Cancer Human Plasma Acquire fresh/frozen Ovarian Cancer plasma based on patient demographics, disease stage, treatment and history.
- SARS-CoV-2 (COVID-19) Human Biological Samples Search for available SARS-CoV-2 human biological samples
In Vitro ADME
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
- Red Blood Cell (RBC) Partitioning (Blood/Plasma Ratio) Measure the distribution of a compound between red blood cells and plasma.
In Vitro Assays
- Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
- Cell Proliferation Measure cell number, cell viability and cell division.
- Human Custom TMA For requesting Human Custom Microarray Services
In Vitro Pharmacology
- Protease Assay Measure protease activity in biochemical and cell-based assays.
In Vitro Toxicology
- Cytotoxicity Test for effects on cell viability and proliferation
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Non-Human Biospecimen
- Monkey / Non-Human Primate / NHP Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
- Monkey / Non-Human Primate / NHP Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
- Monkey / Non-Human Primate / NHP Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Oncology Models
- Cachexia Models Measure therapeutic endpoints in animal models of cachexia.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Protein Sciences
- Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
- Protein Purification Isolate native or recombinant proteins from a sample.
- Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
REACH Services
- OECD 420: Acute Oral Toxicity - Fixed Dose Procedure A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use...
- OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.
Scientific Data Services
- In Silico Genomics/Transcriptomics Data Analysis Interpret DNA sequencing and microarray data.
Specialty Dosing Routes
- Dermal Toxicology Assess toxicity in rodent dermal testing models.
- Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
Other services
- New Request
- Website
- nbioservice.com/en/home
Where it operates
Sites by country, with the cities in each.
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Russia 2 sites
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Armenia 1 site
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