BioCydex

BioCydex is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1

Countries 1

Type of company: Small business

Bioimaging

Electron Microscopy Examine the fine structures of molecules, cells and tissues with sub-nanometer resolution.

Biomarkers

Antioxidant Assays Use biochemical, cell-based or in vivo assays to measure total antioxidant capacity.
Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.

Cell Culture and Characterization

Adherent Cell Culture Grow monolayers of anchorage-dependent cells.
Cell Culture Culture primary or immortalized cell lines.

Chemical and Compound Analysis

API Physical Characteristics Characterize physical and chemical properties of new drug molecules to develop safe, effective, and stable dosage forms.
Chemical Stability Measure the stability of small molecules in solution.
Differential Scanning Calorimetry Elucidate the thermodynamics associated with conformational transitions.
Dissolution Profiling Measure release of API from formulation (tablet or capsules) under GMP guidelines.
Elemental Impurity Analysis Identify and evaluate the presence of heavy metals in pharmaceuticals.
Excipient Compatibility Test excipients for drug formulation, effects of temperature, time, humidity, pH and light exposure as well as excipient release.

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High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
Liquid Chromatography Separate substances using a mobile and stationary phase.
MALDI-TOF Analysis Use mass spectrometry technique to analyze compound, biomolecules and large organic molecules.
Melting Point Use melting point analysis to characterize compounds based on calorimetry and thermodynamic data.
NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
Particle Size Analysis Measure particle size distribution and characterize particle size, porosity and composition.
Photostability Measure drug degradation rates after exposure to various light sources.
Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
Structural Chemistry Examine the relationship between protein structure and function.
Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.
UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.

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Chemistry, Manufacturing and Controls (CMC)

Drug Formulation Combine substances including the active drug into a final product with the desired metabolic and therapeutic properties.
Drug Product Stability Use accelerated stress conditions to determine degradation pathways and identify manufacturing issues.
Thermal Analysis Characterize compounds based on calorimetry and thermodynamic data.

Discovery Chemistry

Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
Method Development and Validation Develop and validate methods for synthesis and scale up of drug candidates.
UV and IR Profiling Analyze the integrity of a compound or large biomolecule.

In Vitro Assays

Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
Cell Proliferation Measure cell number, cell viability and cell division.
Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation

Protein Sciences

LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
X-Ray Crystallography Elucidate structures of biological macromolecules such as proteins and nucleic acids.

Testing Services

Accelerated Stability Determine shelf life of drug formulations by comparing API breakdown at elevated temperature.
Elevated Temperature Stability Determine the stability of a product at elevated temperature.
Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.

France Poitiers 1 site

At BioCydex, we develop products and procedures designed for the formulation and delivery of active principles in the field of Human Health and Biological engineering improving their solubility, stability and bioavailability. BioCydex assists you throughout the development of your product including the determination and characterization of degradation products and the validation of chemical and physico-analytical methods (HPLC, NMR, IR,…) under US and European Pharmacopoeia guidelines.

Website: www.biocydex.com

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