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WuXi Biologics

WuXi Biologics is listed as a large business research supplier in the Scientist.com network, with 12 sites in 4 countries.

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Sites 12
Countries 4

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Large business

Agricultural Sciences Compliance and Quality Control Measures

  • Production and Preservation Assistance with the transfer of primary products to end consumer.

Antibodies

  • Antibody based Assay Development Create specific and sensitive assays for the immunodetection of disease-specific target antigens.
  • Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
  • Antibody Detection Quantitate, localize and visualize proteins and other antigens.
  • Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
  • Antibody Isotype Switching Modify antibody isotypes from any species to any human IgG isotype.
  • Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
Show all 29 in Antibodies 23 more
  • Antibody Protein De Novo Sequencing Sequence antibody proteins using multiple enzyme digestion and high-resolution LC-MS/MS.
  • Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.
  • Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
  • Antibody-Dependent Cell-Mediated Cytotoxicity Request services related to cell-mediated immune defense.
  • Antibody-Drug Conjugation Improve therapeutic properties of an antibody or drug by joining them together.
  • Antigen Specific T-cells T cell lines that recognize specific peptide antigens to enable analysis of T cell immunity.
  • Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
  • Custom Antibodies Design and produce polyclonal and monoclonal antibodies.
  • Direct Antibody Labeling Conjugate a primary antibody to a label for direct antigen detection.
  • Epitope Mapping Map the antibody-antigen binding region to define protein-protein interaction sites.
  • Hybridoma Sequencing/Antibody Sequencing Determine the sequences of monoclonal antibodies.
  • In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
  • Monoclonal/Polyclonal Antibody Development Develop a monoclonal and/or polyclonal antibody.
  • OmniRat Transgenic Animal Platform Produce humanized antibodies using a transgenic rat platform.
  • Pepscan Analysis Screen overlapping peptide sequences to identify linear epitopes.
  • Phosphospecific Antibodies Create antibodies to detect phosphorylated protein targets.
  • Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
  • Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
  • Rabbit Monoclonal Antibody Development Develop monoclonal antibodies using rabbit as the host animal.
  • Recombinant Antibody Production Request services related to antibody production services.
  • SARS-CoV-2 (COVID-19) Antibodies Search for available SARS-COV-2 antibodies
  • SARS-CoV-2 (COVID-19) Protein and Antigen Search for available SARS-CoV-2 proteins and antigens
  • Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.

Biomarkers

  • Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
  • Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
  • Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
  • Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
  • Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
  • Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Show all 11 in Biomarkers 5 more
  • Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
  • In Vivo Apoptosis Detection Visualize and quantify apoptosis in real time.
  • Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.
  • Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
  • Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Show all 253 services 240 more

Cell Culture and Characterization

  • Bacterial Cell Culture Culture and Grow bacterial cells.
  • Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
  • Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
  • Cell Line Construction Create new recombinant cell lines to exact specifications.
  • Endotoxin Characterization Identify specific molecular structure (e.g., Lipid A profiling), determine bacterial source/strain, and assess biological potency of endotoxins
  • In Vitro Hydrogel-Based Culture of PDXs Enable the extended laboratory culture of cancer PDXs and other primary cells in 3D.
Show all 9 in Cell Culture and Characterization 3 more
  • Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
  • Signaling Pathways Find proteins, assays and custom reagents for the analysis of cell signaling pathways.
  • Single Cell Services Request services to perform genomics, transcriptomics, proteomics, metabolomics and cell–cell interactions at the single cell level

Chemical and Compound Analysis

  • Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
  • Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
  • Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
  • High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
  • Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
  • Ion Exchange Chromatography Separate and detect analytes.
Show all 16 in Chemical and Compound Analysis 10 more
  • Liquid Chromatography Separate substances using a mobile and stationary phase.
  • Natural Product Libraries Find microbial, botanical and marine sources of natural products.
  • NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
  • NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
  • Protein Crystallization Create high quality protein-ligand crystals for x-ray diffraction studies.
  • Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
  • Protein Structure Determine the three dimensional structure of a protein by NMR or x-ray crystallography.
  • Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
  • Spray Drying Convert a liquid into a powder by rapidly drying the mixture and removing the moisture component.
  • Structural Chemistry Examine the relationship between protein structure and function.

Chemical and Compound Testing

  • Limulus Amebocyte Lysate (LAL) Test Detect bacterial endotoxins in raw materials used for the production of cosmetics products.
  • USP <85> Bacterial Endotoxin Test Test to detect or quantify bacterial endotoxins that may be present in or on a sample.

Chemistry, Manufacturing and Controls (CMC)

  • API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
  • Bi-specific Antibodies Create a protein made of fragments of two monoclonal antibodies that bind to different antigens.
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Crystallization studies Crystallization studies
  • GMP Synthesis Synthesize APIs including small molecules, formulations and protein-based drugs under GMP compliance.
  • Integrated Antibody Development Package-Europe Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...

Clinical Consulting

  • Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.

Clinical Trials

  • Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.

Data Science/Bioinformatics

  • In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
  • In Silico Epigenetic Compound Library Screening Use computer-aided methods to discover new compounds against key regulators of epigenetic signaling.
  • In Silico Protein Microarray Analysis Use software to visualize and evaluate protein function and expression on a large scale.
  • In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.

Discovery Chemistry

  • Fragment Libraries Find fragment libraries for screening against a protein or cellular target.
  • HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.
  • Large Scale Purification Purify gram to kilogram amounts of recombinantly-expressed or wild-type proteins.
  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.

Disease Models

  • Cough Models Test the therapeutic efficacy of drug candidates in cough models.
  • LPS Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
  • OVA Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
  • Pulmonary Fibrosis Models Measure therapeutic endpoints in animal models of pulmonary fibrosis.

DNA & RNA

  • Bisulfite Seq DNA Methylation Analysis Determine DNA methylation status at single-base resolution
  • cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
  • cDNA library construction Generate a library of recombinant cDNA clones.
  • Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
  • CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
  • DNA Library Screening Screen genomic or cDNA libraries for positive clones.
Show all 34 in DNA & RNA 28 more
  • DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
  • DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
  • DNA Sequencing Determine the nucleotide sequence of DNA samples.
  • DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
  • DNA/RNA Extraction & Purification DNA/RNA Extraction & Purification.
  • Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
  • Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
  • Genomic DNA cloning Clone and propagate genomic DNA inserts of 5-50kb.
  • Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
  • Genotyping Examine a DNA sequence to identify specific genetic varients .
  • Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
  • mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
  • Multiplex Cellular miRNA Assay Use Firefly™ technology for multiplex cellular microRNA profiling.
  • NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
  • Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
  • PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
  • Plant siRNA Design Create selective and potent small interfering RNA constructs for plant gene analysis or crop improvement.
  • Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
  • qPCR Analysis Measure the accumulation of PCR products in real time.
  • RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
  • RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
  • RNA Sequencing Use Next Generation Sequencing techniques to Identify RNA transcripts, examine differential expression patterns and analyze splice variants.
  • RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
  • Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.
  • shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.
  • siRNA Synthesis Produce high quality siRNAs for gene silencing studies.
  • SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
  • Total RNA Sequencing Identify novel RNA transcripts and detect gene expression changes.

Drug Development

  • Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
  • Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.

Human Biological Samples

  • Human Cell Products For requesting human cell by products like proteins, lysates, lysosomes etc

In Vitro ADME

  • Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
  • Isotopic Labeling Track labeled isotopes through a metabolic pathway or cell by measuring mass, vibrational mode or radioactive decay.

In Vitro Assays

  • Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
  • Anti-thrombin Assays Use clotting and chromogenic assays to detect and classify anti-thrombin deficiency.
  • Antivirals Measure anti-viral activity in biochemical and cell assays.
  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Apoptotic Cell Staining Detect apoptotic cells in culture.
  • Assay Development Construct or create new assays or modify existing ones.
Show all 16 in In Vitro Assays 10 more
  • Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • Cell Proliferation Measure cell number, cell viability and cell division.
  • ELISpot Assay and Testing Detect low levels of antigens.
  • Glycobiology Study the structure biosynthesis and biology of carbohydrates
  • In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
  • Microbiology Study microbes and their role in human health.
  • SARS-CoV-2 (COVID-19) Assays Search for Available SARS-CoV-2 Assays
  • Serine Protease Assay Detect apoptosis by measuring protease activity.
  • Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Pharmacology

  • Calcium Channel Assays Use biochemical, cell-based or in vivo assays to measure calcium channel activity.
  • Chloride Channel Assays Use biochemical, cell-based or in vivo assays to measure chloride channel activity.
  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
  • Immuno-oncology Targets Develop drugs that take advantage of the immune system to target cancer cells.
  • In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
Show all 24 in In Vitro Pharmacology 18 more
  • In Vitro Oncology Models Use cell-based and biochemical models of cancer.
  • Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
  • Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
  • Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
  • Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
  • Phosphodiesterase Assays Measure phosphodiesterase activity in biochemical and cell-based assays.
  • Polymerase Assays Measure polymerase activity in biochemical and cell-based assays.
  • Potassium Channel Assays Use biochemical, cell-based or in vivo assays to measure potassium channel activity.
  • Protease Assay Measure protease activity in biochemical and cell-based assays.
  • Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
  • Protein/Enzyme Targets For requesting Protein/Enzyme Targets
  • Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
  • SELEX Select and identify highly specific aptamers with binding affinities comparable to traditional antibodies.
  • Sodium Channel Assays Use biochemical, cell-based or in vivo assays to measure sodium channel activity.
  • Target Characterization Characterize potential drug targets during the drug discovery process.
  • Target Identification Identify the target(s) of a biologically active substance.
  • Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
  • Ubiquitin Ligase Assays Measure ligase enzyme activity in the presence of cofactors or chemical modifiers.

In Vitro Toxicology

  • ADCC and CDC Assay Services Measure toxicity of antibodies.
  • Cardiotoxicity Evaluate the effect of a compound on heart electrophysiology and muscle function.
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
  • Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.

In Vivo ADME

  • Tissue Distribution Study the tissues in which a compound or its metabolites, accumulate.

Non-Human Biospecimen

  • Dog / Canine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
  • Dog / Canine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
  • Dog / Canine Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
  • Guinea Pig Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
  • Guinea Pig Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
  • Guinea Pig Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
Show all 19 in Non-Human Biospecimen 13 more
  • Monkey / Non-Human Primate / NHP Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
  • Monkey / Non-Human Primate / NHP Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
  • Monkey / Non-Human Primate / NHP Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
  • Mouse Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
  • Mouse Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
  • Mouse Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
  • Pig / Minipig / Porcine Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
  • Pig / Minipig / Porcine Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
  • Rabbit Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
  • Rabbit Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.
  • Rat Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.
  • Rat Cells Acquire fresh or frozen cells including but not limited to RBCs, WBCs, PBMCs, endothelial cells, T cells, fibroblasts, hepatocytes, splenocytes, etc.
  • Rat Tissues Acquire fresh or frozen tissues including but not limited to those from the central nervous system, endocrine system, gastrointestinal system, integumentary system, reproductive system, lymphatic system, etc.

Oncology Models

  • Oral Xenograft Measure therapeutic endpoints in oral cancer models as well as cancer models related to the Pharynx.
  • Reproductive System PDX Patient derived xenografts relating to reproductive systems. This includes PDX from reproductive organs such as the Ovaries, Cervix, Breasts, Testes, Prostate, and Scrotum.
  • Reproductive System Xenografts Xenografts relating and derived from the reproductive systems. This includes samples from the ovaries, cervix, vulva, uterus, testes, scrotum, and prostate.
  • T11 (Breast Cancer) Measure therapeutic endpoints in animal models of breast cancer.
  • Xenograft Models Measure therapeutic endpoints in cancer models using tumor cells transplanted from a donor of a different species.

Other Specialty Toxicology

  • Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).

Pharmacovigilance

  • GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Product Orders

  • Kits and Reagents Submit a request to multiple vendors for kits and reagents.

Protein Sciences

  • Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
  • Affinity Tag Purification Purify proteins under physiological conditions at their native cellular levels.
  • Analytical Ultracentrifugation Characterize the interactions and properties of macromolecules in solution.
  • Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
  • Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
  • Carbohydrate Structure Characterization Use analytical tools to elucidate carbohydrate structure and physiochemical properties.
Show all 44 in Protein Sciences 38 more
  • Cytokines Find recombinant cytokines or cytokine assays.
  • ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
  • Fluorophore Protein Conjugation Attach a fluorescent probe to a protein.
  • Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
  • Host Cell Protein Analysis Measure contamination of biologics with host proteins by using sequencing, chromatography and the LAL test.
  • Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
  • Large Scale Protein Production Produce large amounts of protein using fermentors, wave mixers, bioreactors, and large-scale purification workflows.
  • LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
  • Lentivirus Production Develop lentiviruses and production protocols.
  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • Mass Spectrometry-Based Proteomics Detect histone post-translational modifications (hPTMs), histone variants, and interactomes at chromatin regions.
  • N-terminal Sequencing Determine the amino acid sequence of an intact protein from its N-terminus.
  • Neoantigen Development Develop neoantigens for oncological therapeutics for vaccine development.
  • NMR Determine molecular and protein structure, and validate sample integrity.
  • PEG Protein Conjugation Improve the therapeutic or pharmacokinetic properties of a protein by pegylation.
  • Peptide Array Use biologically active synthetic peptides arranged in a high density format to assess protein interaction.
  • Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
  • Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
  • Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
  • Phage Display Use in vitro screening method to identify protein binding partners.
  • Protein Binding Determine drug-protein binding interactions
  • Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
  • Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
  • Protein Identification Uncover or confirm the identity of a protein.
  • Protein Interaction Measure the interaction of a protein to other macromolecules or peptide ligands.
  • Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
  • Protein Products Find native and recombinant proteins and peptides.
  • Protein Purification Isolate native or recombinant proteins from a sample.
  • Protein Sequencing Determine the amino acid sequence of protein or peptide.
  • Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
  • Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
  • Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.
  • Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.
  • Virus Production Produce high titer viruses, viral expression vectors and vaccines.
  • Western Blots Detect specific proteins in a sample of tissue homogenate or extract.
  • Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
  • Yeast Two Hybrid Search novel interactions or confirm hypothesized protein-protein interactions using pairwise assays.

REACH Services

  • OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
  • OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.

Safety Pharmacology

  • Off Target Effects Assess toxicities by body weight, clinical chemistry, hematology, urinalysis and terminal necropsy and pathology.

Scientific Data Services

  • Bioinformatics Bioinformatics is a powerful method of storing, retrieving and analyzing biological data.

Specialty Dosing Routes

  • Intracameral Implant Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct an intracameral implant toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct an intravitreal ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct an intravitreal ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct a topical ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.

Other services

  • New Request &nbsp;
  • proxy-CRISPR Gain access to previously unreachable areas of the genome via proxy-CRISPR, a proximal CRISPR targeting method that restores FnCas9 nuclease activity.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • China Suzhou, WuXi, Hangzhou, Hong Kong, Shanghai, Wuxi Shi 8 sites
  • United States New Jersey 2 sites
  • Ireland Co Louth 1 site
  • United Kingdom London 1 site

Source: Scientist.com supplier network (site locations)

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