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Suven Life Sciences
Suven Life Sciences is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country and 5 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Biomarkers
- Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
Chemical and Compound Analysis
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
- Solubility Studies Analyze substances for kinetics of solubility using nephelometry and UV-Vis spectrometry.
Chemical and Compound Testing
- Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
Disease Models
- Cognition Models Measure therapeutic endpoints in animal models of cognition.
- General Pain Models Measure therapeutic endpoints in animal models of general pain.
- In Vivo Technologies Models Carry out EEGs, cognition assessment, microdialysis, electrophysiology, MRI, ultrasound and tomographic analysis.
- Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
- Microdialysis Models Measure the effect of drug candidates on neurotransmission in rat or mouse models.
- Morris Water Maze Investigate spatial learning and memory in rodents.
Show all 9 in Disease Models
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Pain Models Test therapeutic efficacy of drug candidate in pain model.
- Visceral Pain Models Measure therapeutic endpoints in animal models of visceral pain.
General in vivo Toxicology
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Show all 31 services
In Vitro ADME
- HT ADME (High-Throughput Absorption, Distribution, Metabolism and Excretion) Analyze the process and effects of a chemical that is ingested by an organism using an advanced technological screening process. Use for drug...
- Metabolic Stability Measure metabolic vulnerability to drug metabolizing enzymes using cell-free, cell-based and in vivo assays.
In Vitro Assays
- Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
- Monoamine Transporter Assays Measure monoamine neurotransmitter uptake in cultured cells.
In Vitro Pharmacology
- Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
- G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
- Ion Channels Use fluorometry, electrophysiology and radiometric binding assays to measure ion channel activity.
In Vitro Toxicology
- hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
In Vivo Pharmacokinetics
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Model Development
- Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.
Protein Sciences
- Enzymology Enzymology studies the biochemical activity, structure, and function of enzymes. Two key area of Enzymology are Cytochrome P450...
- Protein Binding Determine drug-protein binding interactions
REACH Services
- OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
- OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
- OECD 475: Mammalian Bone Marrow Chromosomal Aberration Test The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese...
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
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India 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
p<>. Suven Discovery has 8 years experience in discovery and development of several small molecules to clinic in CNS; serving pharma and biotech industry through collaborative research (Eli-Lilly) and fee-for-service (AstraZeneca, BMS, Johnson-Johnson, Pfizer, Abbott, Lundbeck, Reviva, Theravance, Onconova, Kareus) p<>. Suven Discovery Services: Medicinal Chemistry, Process Chemistry, Analytical Chemistry, Structure elucidation, Impurities Metabolite Synthesis; Physicochemical properties; In-vitro screening (Receptors-Enzymes); Assay development; In-vitro and In-vivo Drug -metabolism...
Show the full description
p<>. Suven Discovery has 8 years experience in discovery and development of several small molecules to clinic in CNS; serving pharma and biotech industry through collaborative research (Eli-Lilly) and fee-for-service (AstraZeneca, BMS, Johnson-Johnson, Pfizer, Abbott, Lundbeck, Reviva, Theravance, Onconova, Kareus)
p<>. Suven Discovery Services: Medicinal Chemistry, Process Chemistry, Analytical Chemistry, Structure elucidation, Impurities Metabolite Synthesis; Physicochemical properties; In-vitro screening (Receptors-Enzymes); Assay development; In-vitro and In-vivo Drug -metabolism & Pharmacokinetics in rodents, non-rodents; Brain penetration; Microdialysis; Receptor Occupancy; CNS Pharmacology; Safety Pharmacology; In-vitro and In-vivo rodent Toxicology; Histopathalogy; Clinical Pathology, Bioanalysis.
p<>. Suven Discovery offers Aggressive timelines together with high scientific quality and documentation for your decision making of molecule progression in drug discovery.
We provide services in:
- Chromosomal Aberration Tests - CHO, human lymphocyte, rodent
- Binding Assays - protein, radioligand, monoamine transporter
- Animal Models of Pain - neuropathy, injury, pain, visceral, spinal nerve, constriction, forced swim, cognition
- Memory Testing: water maze, arm maze, induced memory deficit
- LCMS Bioanalysis - metabolites, Caco-2, receptor occupancy, GLP, partitioning, CYP
- Website
- www.suven.com
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