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Research supplier
iC42 Bioanalytics
iC42 Bioanalytics is listed as an academic core research supplier in the Scientist.com network, with 1 site in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Academic core
Chemical and Compound Analysis
- GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
- Non GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
In Vitro ADME
- Compound Distribution Determine the metabolic fate of a drug candidate in tissue and organs of diseased and normal animal models.
- CYP Inhibition Assay Assess the inactivation and inhibition of cytochrome P450 (CYP450) in microsomes isolated from primary human hepatocytes or liver.
- CYP Isozyme Mapping Determine the isozymes of cytochrome P450 (CYP450) involved in the metabolism of a drug candidate.
- Cytochrome P450s Assess the inhibition or induction of the various isozymes of cytochrome P450s by drug candidates.
- Drug Drug Interactions Determine whether a substance affects the activity of a drug when both are administered together.
- Metabolic Stability in Microsomes Assess the susceptibility of drugs to metabolism by Phase I (CYP450) and Phase II enzymes in liver microsomes.
Show all 12 in In Vitro ADME
- Metabolite Quantification Quantify drug metabolites formed after drug administration to an animal model or patient.
- Metabolite Structural Elucidation Use analytical tools to characterize metabolite structure.
- Metabolite Synthesis Synthesize drug metabolites that are formed after administration of drug to an animal model or patient.
- Phase I Metabolism Use enzymes such as cytochrome P450 oxidases to introduce reactive or polar groups into xenobiotics.
- Phase II Metabolism Use transferase enzymes such as glutathione S-transferases to conjugate phase I xenobiotics to polar compounds.
- Plasma Stability Assay Determine degradation rate of drug candidates in plasma.
In Vitro Assays
- Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
Show all 20 services
Protein Sciences
- SILAC Enable incorporation of isotopic labels in proteins for mass spectrometry-based quantitative proteomics.
Target Animal and Human Food Safety
- Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.
Where it operates
Sites by country, with the cities in each.
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
iC42 Clinical Research & Development is a regulatory compliant laboratory (GLP, CAP and CLIA certified) and an extension of one of the leading Medical Schools in the United States, the University of Colorado and its Department of Anesthesiology.
- Website
- www.bioanalytics.us
Work with iC42 Bioanalytics on Scientist.com
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