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Porsolt
Porsolt is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 1 country and 2 service areas.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Biomarkers
- Anatomic Pathology Do macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.
- Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.
- Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
- Digital Pathology Acquire, manage and interpret pathology information generated from a digital image of a slide preparation of cells or tissue.
- Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
- Hematoxylin & Eosin (H&E) Staining Visualize microscopic structures in cells or tissues.
Show all 14 in Biomarkers
- Histopathology Evaluate slide preparation of cells or tissues for abnormal features.
- Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
- Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
- Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
- Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
- Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
- Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
- Prognostic Biomarkers Discovery Identify candidate biomarkers representative of disease progression without treatment.
Cell Culture and Characterization
- Cell and Tissue Histology Prepare and stain frozen, fixed and embedded (FFPE) tissue samples.
- Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
- H & E Services For requesting services related to H&E Services
- Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.
- Trichrome Staining Use a variety of techniques for the selective visualization of muscle, collagen fibers, fibrin and erythrocytes.
Chemical and Compound Analysis
- Non GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.
- Sample Bioanalysis Determination of concentration of an analyte in biological sample.
Show all 80 services
Clinical Trials
- Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.
Data Science/Bioinformatics
- Translational Biomarker Discovery An approach to finding markers that change in response to a drug or that identify a group that responds favorably to a specific therapy. These can be omics, molecular, histologic, radiologic, etc.
- Translational Data Analysis Analysis that helps you make sense of your translational data
Disease Models
- Acute Liver Failure Models Measure therapeutic endpoints in animal models of acute liver failure.
- Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
- Atopic Dermatitis Models Measure therapeutic endpoints in animal models of atopic dermatitis.
- Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
- Cardiovascular Metabolics Models Measure therapeutic endpoints in animal models of cardiovascular disorders.
- Cardiovascular Models Test the therapeutic efficacy of drug candidates in cardiovacular disease models.
Show all 32 in Disease Models
- Chronic Kidney Disease Models Measure therapeutic endpoints in animal models of chronic kidney disease.
- Cognition Models Measure therapeutic endpoints in animal models of cognition.
- Cough Models Test the therapeutic efficacy of drug candidates in cough models.
- Dermatology Models Measure therapeutic endpoints in animal models of dermatological disorders.
- Electroencephalogram EEG Models Record electrical activity along the scalp of animal models or human patients.
- Emesis Models Measure therapeutic endpoints in animal models of emesis.
- fa/fa Zucker Diabetic Rats Use a single animal species to create one or more disease models for diabetes and obesity.
- General Pain Models Measure therapeutic endpoints in animal models of general pain.
- Inflammatory Pain Models Measure therapeutic endpoints in animal models of inflammatory pain.
- Interstitial Cystitis Models Measure therapeutic endpoints in animal models of interstitial cystitis.
- Irritant Models Measure therapeutic endpoints in animal models of skin irritation.
- Ischemia Models Measure therapeutic endpoints in animal models of ischemia.
- Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
- Neuroscience Models Test therapeutic efficacy of drug candidate in neurological disease model.
- Ob/ob Mouse Use a single animal species to create one or more disease models obesity and angiogenesis.
- Obese Mice Use a single animal species to create one or more disease models for diet-induced obesity and type II diabetes.
- Osteoarthritic Pain Models Measure therapeutic endpoints in animal models of osteoarthritic pain.
- Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
- OVA Lung Inflammation Models Measure therapeutic endpoints in animal models of inflammation.
- Pain Endpoints Models Measure therapeutic endpoints in animal models of pain.
- Pain Model Consulting Expert advice to better evaluate and understand pain thresholds and phenomena within living organisms. Can be used to evaluate pain associated with specific diseases or injuries affecting the sensory and nervous systems.
- Pain Models Test therapeutic efficacy of drug candidate in pain model.
- Stroke Models Measure therapeutic endpoints in animal models of stroke.
- Thrombosis Models Measure therapeutic endpoints in animal models of thrombosis.
- Visceral Pain Models Measure therapeutic endpoints in animal models of visceral pain.
- Wound Healing Models Measure therapeutic endpoints in animal models of wound healing.
DNA & RNA
- qPCR Analysis Measure the accumulation of PCR products in real time.
- Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.
Drug Development
- Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
- Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.
General in vivo Toxicology
- General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
- Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Human Biological Samples
- Human Organs-On-Chips Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
In Vitro Pharmacology
- Glucose Transporter Assays Use biochemical, cell-based or in vitro assays to measure glucose transporter activity.
- In Vitro Diabetes Models Measure insulin stimulation of glucose uptake and metabolism of lipids including cholesterol and triglycerides.
- In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.
- In Vitro Neural Models Use cultured neurons, neuronal progenitor cells and stem cell differentiation to create cellular models of neurological disease.
- Nucleoside Transporter Assays Use biochemical, cell-based or in vivo assays to measure nucleoside transporter activity.
In Vivo Pharmacokinetics
- In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
- Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Model Development
- Custom Model Development Develop a custom disease model.
- Transgenic Models Create animal models engineered for use in a specific therapeutic area.
Oncology Models
- Cachexia Models Measure therapeutic endpoints in animal models of cachexia.
- Oncology Models Use model organisms to test the therapeutic efficacy of cancer drug candidates.
Safety Pharmacology
- Abuse and Dependence Liability Testing Determine the abuse or dependence potential of a therapeutic.
- Abuse Liability Determine the dependence potential of a therapeutic.
- CNS Behavioral Measure safety toxicology effects of CNS and behavioral drugs.
- Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
Specialty Dosing Routes
- Dermal Toxicology Assess toxicity in rodent dermal testing models.
Other services
- New Request
Service areas:
Where it operates
Sites by country, with the cities in each.
-
France 2 sites
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
About Porsolt SAS Porsolt is a long-established preclinical CRO, having started operations in 1984 under the name ITEM-Labo. Porsolt has obtained an international reputation for expertise in physiopathological models, customized procedures and tailored solutions for discovering treatments of psychiatric and neurological disorders, acute and chronic pain, inflammation, cardiac and vascular diseases, and metabolic and eating disorders. Porsolt also offers services for safety evaluation of drug candidates from screening to pre-Phase 1 regulatory studies (ICH S7), in full compliance with GLP...
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About Porsolt SAS
Porsolt is a long-established preclinical CRO, having started operations in 1984 under the name ITEM-Labo. Porsolt has obtained an international reputation for expertise in physiopathological models, customized procedures and tailored solutions for discovering treatments of psychiatric and neurological disorders, acute and chronic pain, inflammation, cardiac and vascular diseases, and metabolic and eating disorders. Porsolt also offers services for safety evaluation of drug candidates from screening to pre-Phase 1 regulatory studies (ICH S7), in full compliance with GLP. Porsolt’s safety program includes full assessment of arrhythmogenic risk and abuse/dependence liability. Porsolt is headquartered in France with facilities in Paris and Laval. In late 2010 Porsolt opened a subsidiary in Texas (USA) to carry out studies in primates.
For additional information about the organization, please visit www.porsolt.com.
- Website
- www.porsolt.com
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