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ToxBy.Design

ToxBy.Design is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Agricultural Sciences Compliance and Quality Control Measures

  • Juvenile Growth Test Examine the adverse effects of recurrent and long-term toxin exposure on juvenile fish development.
  • Sediment-Water Toxicity Test Isolate the water of a sediment-based habitat to analyze the properties for toxicity evaluation.

Biomarkers

  • Antimicrobial Effectiveness Testing Measure the efficacy of anti-microbial preservatives added to a product.
  • Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
  • Histopathology Evaluate slide preparation of cells or tissues for abnormal features.

Cell Culture and Characterization

  • Cell Line Characterization Track source history and characterize cell lines to establish identity, purity and stability.
  • Histology Examine by microscopy the anatomy of cells and tissues of clinical patients and animal models.

Chemical and Compound Analysis

  • Adsorption/Desorption Studies Obtain data on groundwater risk assessment.
  • Impurities in API Risk assessment Create a risk-based control strategy to determine any impurities in Active Pharmaceutical Ingredients (API).

Chemical and Compound Testing

  • Occupational Exposure Limits (OEL) Reports Develop and determine the Occupational Exposure Limit of a substance or compound. The OEL is the value which indicates the level of exposure to be safe in the workplace.
  • USP <2022> Microbiological Procedures for Absence of Specified Microorganisms Determine the absence of objectionable organisms in nutritional supplements.

Chemistry, Manufacturing and Controls (CMC)

  • API manufacturing process development, tech transfer and validation API manufacturing process development, tech transfer and validation
  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Impurities in Drugs Risk Assessment Create a risk-based control strategy to determine any toxic elemental impurities that may be present in human medicines.
  • Subcellular Fraction Test System Obtain human, minipig, mouse, or rat dermal microsomes as in-stock standard test systems for the development of safer topical and transdermal products.
Show all 207 services 192 more

Developmental and Reproductive Toxicology (DART)

  • Embryo-Fetal Development (EFD) Study (Segment II) - Mouse Conduct a study to determine the effect of compound exposure on the pregnant mouse and the developing fetus.
  • Embryo-Fetal Development (EFD) Study (Segment II) - Other Species Conduct a study to determine the effect of compound exposure on the pregnant animal and the developing fetus.
  • Embryo-Fetal Development (EFD) Study (Segment II) - Rabbit Conduct a study to determine the effect of compound exposure on the pregnant rabbit and the developing fetus.
  • Embryo-Fetal Development (EFD) Study (Segment II) - Rat Conduct a study to determine the effect of compound exposure on the pregnant rat and the developing fetus.
  • Enhanced Pre/Post-Natal Development Study (ePPND) - Monkey / Non-human Primate Conduct a study that combines in utero and postnatal assessments of your compound in monkeys/non-human primates.
  • Fertility and Embryonic Development Study (Segment I) - Mouse Conduct a study to determine the effect of your compound on the estrous cycle, spermatogenesis/male reproductive organs, fertility of parents, and development of the embryo in mice.
Show all 15 in Developmental and Reproductive Toxicology (DART) 9 more
  • Fertility and Embryonic Development Study (Segment I) - Other Species Conduct a study to determine the effect of your compound on the estrous cycle, spermatogenesis/male reproductive organs, fertility of parents, and development of the embryo in other species.
  • Fertility and Embryonic Development Study (Segment I) - Rat Conduct a study to determine the effect of your compound on the estrous cycle, spermatogenesis/male reproductive organs, fertility of parents, and development of the embryo in rats.
  • Juvenile Toxicity Study - Dog / Canine Conduct a study to determine the differences in toxicity between immature and mature systems in dogs.
  • Juvenile Toxicity Study - Other Species Conduct a study to determine the differences in toxicity between immature and mature systems in other species.
  • Juvenile Toxicity Study - Rat Conduct a study to determine the differences in toxicity between immature and mature systems in rats.
  • Pre/Post-Natal Development (PPND) Study (Segment III) - Mouse Conduct a study to quantify the effect of your compound on fetal development, parturition, and post-natal development in mice.
  • Pre/Post-Natal Development (PPND) Study (Segment III) - Other Species Conduct a study to quantify the effect of your compound on fetal development, parturition, and post-natal development in other species.
  • Pre/Post-Natal Development (PPND) Study (Segment III) - Rat Conduct a study to quantify the effect of your compound on fetal development, parturition, and post-natal development in rats.
  • Reproductive Toxicology Study adverse sexual function and fertility and examine teratogenicity of compounds.

Discovery Chemistry

  • Extractable and Leachable Assessment Quantify potential impurities from container closures & packaging.

Disease Models

  • Drug-Induced Liver Injury (DILI) Toxicity Assays Use biochemical, cell-based or in vivo assays to measure toxicity from drug-induced liver injury.

Drug Development

  • Chemistry, Manufacturing and Controls (CMC) Consulting Consultant services related to the development of pharmaceutical and biopharmaceutical drug products that are consistently effective, safe and high quality for consumers.
  • Toxicology Consulting Use models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

Environmental Assessment

  • Environment Fate Studies Evaluate the behavior of veterinary drugs and additives under controlled field and lab conditions.
  • Soil Dissipation Studies Find out how products degrade and dissipate in soil under typical use conditions.
  • Terrestrial Effects Studies Assess the exposure and adverse effects of veterinary antibiotics to terrestrial ecosystems.
  • Veterinary Environmental Assessment Assess whether environmental impacts may occur from the manufacture, use, or disposal of veterinary drugs.

Farm & Livestock Solutions

  • OECD 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC) This Test Guideline describes an experimental method using HPLC for the estimation of the adsorption coefficient Koc in soil and in sewage sludge.

General in vivo Toxicology

  • Carcinogenicity Study - Mouse Conduct a repeat dose, chronic carcinogenicity study in mice to determine the tendency of your compound to produce tumors.
  • Carcinogenicity Study - Rat Conduct a repeat dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
  • Effective Dose (ED), 50% Toxicity Test Quantify the diluted toxin needed to induce sub-lethal effects upon constant exposure in half of test organisms.
  • General Toxicology Use in vivo models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.
  • IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
  • Mammalian Toxicology Use toxicity testing models to carry out required FDA or REACH safety testing.
Show all 16 in General in vivo Toxicology 10 more
  • Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
  • Repeat Dose Toxicity Study - Dog / Canine Conduct a repeat dose study in dogs to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Toxicity Study - Monkey / Non-human Primate Conduct a repeat dose study in monkey/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Toxicity Study - Mouse Conduct a repeat dose study in mice to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Toxicity Study - Other Species Conduct a repeat dose study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Toxicity Study - Rat Conduct a repeat dose study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Short-Term Toxicity Tests Acquire preliminary data about the concentrations, exposure duration and effects of a toxin on organisms.
  • Single Dose Acute Toxicity Study - Dog / Canine Conduct a single dose study in Dogs and Canines to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Toxicity Study - Monkey / Non-human Primate Conduct a single dose study in Monkeys and Non-human Primates to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Toxicity Study - Mouse Conduct a single dose study in Mice and Murines to determine the toxicokinetic behavior of your compound.

Human Biological Samples

  • 3D InSight™ Liver Microtissues Perform in vitro assessment of islet function for efficacy and toxicity testing.

In Vitro ADME

  • Permitted Daily Exposure (PDE) Evaluate the health based exposure limits or permitted daily exposure of different medicinal products in shared facilities during manufacturing.

In Vitro Assays

  • 3D Cell Microscopy Assay Investigate cellular and subcellular events in three dimensional 3D cultures by using fluorescence microscopy.
  • 3Screen™ 3D In Vitro Services 3Screen™ Platform enables complete 3D cell culture characterization.
  • Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
  • Apoptotic Cell Staining Detect apoptotic cells in culture.
  • Caspase Assay Detect early to mid stage apoptosis or differentiate apoptosis from necrosis.
  • Invasion Assays Monitor and quantify the ability of cultured cells to permeate real or artificial biological barriers.

In Vitro Pharmacology

  • In Vitro Fertilization Models Measure oocyte maturation, embryo development in culture and sperm fertilizing ability.

In Vitro Toxicology

  • ADCC and CDC Assay Services Measure toxicity of antibodies.
  • Cardiac Channels Measure the arrhythmia producing potential of test compounds.
  • Cardiomyocyte Toxicity Assess cytotoxic effects of pre-clinical compounds on cardiomyocytes.
  • Cardiovascular Toxicology Measure the toxic effects of pre-clinical compounds.
  • Cytotoxicity Test for effects on cell viability and proliferation
  • Cytotoxicity Testing Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
Show all 18 in In Vitro Toxicology 12 more
  • Endothelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the vascular system.
  • Epidermal Cell Toxicity Measure toxicity by quantifying the number of live/dead cells, cell membrane integrity and glutathione (GSH) levels.
  • Hematopoietic Cell Toxicity Examine cytotoxic effects of pre-clinical compounds or biologics on adult stem cells.
  • HepaRG Cells Obtain terminally differentiated and cryopreserved hepatic cells that retain many characteristics of primary human hepatocytes.
  • Hepatocyte Toxicity Assess the cytotoxic effects of pre-clinical compounds on hepatocytes purified from patients and animal models.
  • hERG Inhibition Measure the arrhythmia-producing potential of test compounds.
  • Microelectrode Array Cardiotoxicity Assays Use microelectrode array to measure cardiotoxicity-related activities.
  • Perfused Heart Examine cardiac contractile strength (inotropic effects), heart rate (chronotropic effects) and vascular effects.
  • Short Time Exposure (STE) Test Use in vitro eye irritation tests to assess cytotoxicity in SIRC cells (rabbit corneal cell line).
  • ToxTracker assay An assay for detection of signaling pathways underlying carcinogenicity/genotoxicity.
  • Tubule Epithelial Cell Toxicity Assess the cytotoxic effects of pre-clinical compounds on the kidney.
  • Zebrafish Embryo Toxicity Use a single animal species to create one models of toxicity.

In Vivo Pharmacokinetics

  • Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).

Management Optimization & Development Strategies

  • OECD Regulatory Development Consultation in safety testing, chemical notification and registry within OECD.

Medical Communications

  • Medical Devices Biological Evaluation Report Audit Conduct a bio-compatibility evaluation of medical devices within the human body.
  • Medicinal Product Non- Clinical Outcome Determine potential outcomes for products in a non-clinical setting.
  • Toxicology Reports Create pre-clinical toxicology reports.

Model Development

  • Juvenile Toxicology Assess developmental and reproductive defects due to neurobehavioral, skeletal and muscle growth effects.

Neurotoxicology

  • Single Dose Acute Neurotoxicity Study - Other Species Conduct a single dose study in other species to determine the neurotoxicty of your compound.
  • Single Dose Acute Neurotoxicity Study - Rat Conduct a single dose study in rats to determine the neurotoxicty of your compound.

Other Specialty Toxicology

  • Biosafety Testing Consulting Expert advice to conduct safe and responsible biological procedures and practices.
  • Biosafety Testing In Vitro Test biologics, raw materials, lot release and viral safety
  • Cutaneous Phototoxicity Study - Guinea Pig Conduct a study in guinea pigs to determine if a toxic response is elicited after the initial exposure to your compound and subsequent exposure to light.
  • Cutaneous Phototoxicity Study - Mouse Conduct a study in mice to determine if a toxic response is elicited after the initial exposure to your compound and subsequent exposure to light.
  • Cutaneous Phototoxicity Study - Other Species Conduct a study in other species to determine if a toxic response is elicited after the initial exposure to your compound and subsequent exposure to light.
  • Cutaneous Phototoxicity Study - Rat Conduct a study in rats to determine if a toxic response is elicited after the initial exposure to your compound and subsequent exposure to light.
Show all 10 in Other Specialty Toxicology 4 more
  • Microbial Testing Test samples for microorganisms, identify species, do bioburden analysis and measure endotoxin levels (LAL).
  • Phototoxicity Determine whether drug treatment causes light-activated toxic effects.
  • Semi-Static Acute Toxicity Test Measure toxicity endpoints in aquatic organisms exposed to renewed test solutions at defined intervals of an experiment.
  • Tumorigenicity Testing Test tumor-forming properties of cell products.

REACH Services

  • Hazard, Exposure and Risk Assessment Evaluate the known hazard of a test compound in conjunction with the expected quantity and frequency of exposure.
  • OECD 209: Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation) This Test Guideline is designed to assess the effects of a substance on micro-organisms from activated sludge of waste-water treatment plants by measuring their respiration rate (carbon and/or ammonium oxidation) as...
  • OECD 402: Acute Dermal Toxicity This method provides information on health hazard likely to arise from short-term exposure to a test chemical by dermal route.
  • OECD 403: Acute Inhalation Toxicity This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation.
  • OECD 404: Acute Dermal Irritation/Corrosion This method provides information on health hazard likely to arise from exposure to liquid or solid test substance by dermal application.
  • OECD 405: Acute Eye Irritation/Corrosion This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye.
Show all 34 in REACH Services 28 more
  • OECD 406: Skin Sensitisation This method provides information on health hazard likely to arise from exposure to test substance via intradermical injection and/or epidermical application.
  • OECD 407: Repeated Dose 28-day Oral Toxicity Study in Rodents This method provides information on health hazard likely to arise from exposure to test substance via oral administration.
  • OECD 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents This method provides information on health hazard likely to arise from exposure to test substance via oral administration.
  • OECD 410: Repeated Dose Dermal Toxicity: 21/28-day Study This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance.
  • OECD 411: Subchronic Dermal Toxicity: 90-day Study This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance.
  • OECD 412: Subacute Inhalation Toxicity: 28-Day Study This revised Test Guideline 412 (TG 412) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a limited period of time (28 days), and to provide data...
  • OECD 413: Subchronic Inhalation Toxicity: 90-day Study This revised Test Guideline 413 (TG 413) has been designed to fully characterize test article toxicity by the inhalation route following repeated exposure for a period of 90 days, and to provide data for quantitative...
  • OECD 414: Prenatal Developmental Toxicity Study This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism.
  • OECD 416: Two-Generation Reproduction Toxicity This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive...
  • OECD 420: Acute Oral Toxicity - Fixed Dose Procedure A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use...
  • OECD 421: Reproduction/Developmental Toxicity Screening Test The test substance is administered in graduated doses to several groups of males and females.
  • OECD 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance.
  • OECD 423: Acute Oral toxicity - Acute Toxic Class Method The acute toxic class method set out in this Guideline is a stepwise procedure with the use of 3 animals of a single sex per step. Depending on the mortality and/or the moribund status of the animals, on average 2-4...
  • OECD 425: Acute Oral Toxicity: Up-and-Down Procedure The method permits estimation of an LD50 with a confidence interval and the results allow a substance to be classified for acute toxicity according to the Globally Harmonised System of classification and labelling...
  • OECD 426: Developmental Neurotoxicity Study A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development.
  • OECD 431: In Vitro Skin Corrosion: Human Skin Model Test The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight...
  • OECD 432: In Vitro 3T3 NRU Phototoxicity Test Test the cytotoxic effects of chemical substances and environmental samples on cell membranes.
  • OECD 436: Acute Inhalation Toxicity – Acute Toxic Class Method The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according...
  • OECD 451: Carcinogenicity Studies The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test...
  • OECD 452: Chronic Toxicity Studies Evaluate the direct and indirect impact of prolonged and repeated toxin exposure to test organisms.
  • OECD 471: Bacterial Reverse Mutation Test (Ames) Measure the mutagenic potential of test compounds.
  • OECD 473: In Vitro Mammalian Chromosomal Aberration Test Assess the ability of the test substance to cause structural chromosomal aberrations in cultured mammalian cells.
  • OECD 474: Mammalian Erythrocyte Micronucleus Test The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone...
  • OECD 475: Mammalian Bone Marrow Chromosomal Aberration Test The mammalian in vivo chromosome aberration test is used for the detection of structural chromosome aberrations induced by test compounds in bone marrow cells of animals, usually rodents (rats, mice and Chinese...
  • OECD 476: In Vitro Mammalian Cell Gene Mutation Test (Mouse Lymphoma Assay) Determine if a compound is mutagenic by using cultured mammalian cells.
  • OECD 486: Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo The purpose of the unscheduled DNA synthesis (UDS) test with mammalian liver cells in vivo is to identify substances that induce DNA repair after excision and removal of a stretch of DNA containing a region of damage...
  • OECD 487: In Vitro Mammalian Cell Micronucleus Test Assess whether a test substance induces chromosomal changes in cultured cells.
  • OECD 489: In Vivo Mammalian Alkaline Comet Assay Measure the mitogenic and genotoxic potential of test compounds.

Regulatory Affairs

  • Risk Benefit Assessment Determine ratio of treatment risk to the potential benefits.

Regulatory Consulting

  • Environmental Fate and Ecotoxicology Data Review Identify relevant endpoints for fate and behavior (metabolism and excretion, degradation and soil adsorption) and toxicity (soil organisms, aquatic organisms, and dung fauna) of animal health products.
  • Environmental Risk Assessment Conduct EU and US Environmental Assessment (ERA/EA) phases one and two according to VICH guidelines.
  • Toxicology Data Review Identify relevant toxicological endpoints for “No Observed (Adverse) Effect Level” (NO(A)EL) or “Lowest Observed (Adverse) Effect Level” (LO(A)EL).

Safety Pharmacology

  • Developmental Neurotoxicty Study - Other Species A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development.
  • Immunotoxicity Measure effects of drugs on immune function, allergic hypersensitization and autoimmune toxicity.
  • Microelectrode Array Neurotoxicity Assays Use microelectrode array to measure neurotoxicity-related activities.
  • Repeat Dose Neurotoxicity Study - Other Species Conduct a repeat dose study in other species to determine the neurotoxicity of your compound.
  • Repeat Dose Neurotoxicity Study - Rat Conduct a repeat dose study in rats to determine the neurotoxicity of your compound.
  • Respiratory Toxicology Assess difficulty breathing, altered respiration, blood gas changes and blood pH issues due to adverse reactions.
Show all 8 in Safety Pharmacology 2 more
  • Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.
  • Target Safety Assessment Understand the role of your drug target and assess risks in normal physiology.

Specialty Dosing Routes

  • Chronic Inhalation Carcinogenicity Study - Other Species Conduct a repeat inhalation dose, chronic carcinogenicity study in other species to determine the tendency of your compound to produce tumors.
  • Chronic Inhalation Carcinogenicity Study - Rat Conduct a repeat inhalation dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
  • Chronic Intranasal Carcinogenicity Study - Other Species Conduct a repeat dose intranasal, chronic carcinogenicity study in other species to determine the tendency of your compound to produce tumors.
  • Chronic Intranasal Carcinogenicity Study - Rats Conduct a repeat dose intranasal, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
  • Chronic Intravenous Infusion Carcinogenicity Study - Other Species Conduct a repeat intravenous infusion dose, chronic carcinogenicity study in other species to determine the tendency of your compound to produce tumors.
  • Chronic Intravenous Infusion Carcinogenicity Study - Rat Conduct a repeat intravenous infusion dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
Show all 53 in Specialty Dosing Routes 47 more
  • Dermal Toxicology Assess toxicity in rodent dermal testing models.
  • Inhalation Toxicology Measure toxicity by daily clinical observation, body weight, clinical chemistry, hematology, and terminal necropsy and pathology.
  • Intra-Articular Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered directly to the joint.
  • Intra-Auricular Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered via the ear.
  • Intracameral Implant Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intracameral implant toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Intracameral Implant Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct an intracameral implant toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
  • Intrathecal/Intraspinal Toxicology Conduct a study to determine the toxicity and toxicokinetic behavior of your compound when delivered via the intrathecal space.
  • Intravitreal Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct an intravitreal ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Intravitreal Toxicity and/or Toxicokinetic Study - Minipig Conduct an intravitreal ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
  • Intravitreal Toxicity and/or Toxicokinetic Study - Other Species Conduct an intravitreal ocular toxicity study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct an intravitreal ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Intravitreal Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct an intravitreal ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Lethal Dose (LD), 50% Toxicity Test Measure acute toxicity by identifying the amount of pure toxin required to kill half of the experimental subjects.
  • Ophthalmologic Toxicology Measure toxicity by microscopy, vitrectomy, tonometry, electroretionography and corneal colorimetry.
  • Repeat Dose Inhalation Study - Other Species Conduct a repeat dose inhalation study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Inhalation Study - Rat Conduct a repeat dose inhalation study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Dog / Canine Conduct a repeat dose intranasal study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Monkey / Non-human Primate Conduct a repeat dose intranasal study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Mouse Conduct a repeat dose intranasal study in mice to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Other Species Conduct a repeat dose intranasal study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intranasal Study - Rat Conduct a repeat dose intranasal study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intravenous Infusion Study - Dog / Canine Conduct a repeat dose intravenous infusion study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intravenous Infusion Study - Monkey / Non-human Primate Conduct a repeat dose intravenous infusion study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intravenous Infusion Study - Other Species Conduct a repeat dose intravenous infusion study in other species to determine the toxicity and toxicokinetic behavior of your compound.
  • Repeat Dose Intravenous Infusion Study - Rats Conduct a repeat dose intravenous infusion study in rats to determine the toxicity and toxicokinetic behavior of your compound.
  • Single Dose Acute Inhalation Study - Other Species Conduct a single dose inhalation study in other species to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Inhalation Study - Rat Conduct a single dose inhalation study in rats to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Mouse Conduct a single dose intranasal study in mice to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Other Species Conduct a single dose intranasal study in other species to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intranasal Study - Rat Conduct a single dose intranasal study in rats to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intravenous Infusion Study - Dog / Canine Conduct a single dose intravenous infusion study in dogs/canines to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intravenous Infusion Study - Monkey / Non-human Primate Conduct a single dose intravenous infusion study in monkeys/non-human primates to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intravenous Infusion Study - Other Species Conduct a single dose intravenous infusion study in other species to determine the toxicokinetic behavior of your compound.
  • Single Dose Acute Intravenous Infusion Study - Rats Conduct a single dose intravenous infusion study in rats to determine the toxicokinetic behavior of your compound.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Minipig Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to minipigs.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Monkeys/Non-human Primates Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to monkeys/non-human primates.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Mouse Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to mice.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Other Species Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to other species.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Rabbit Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rabbits.
  • Topical Dermal Toxicity and/or Toxicokinetic Study - Rat Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to rats.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Dog / Canine Conduct a topical ocular toxicity study in dogs/canines to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Minipig Conduct a topical ocular toxicity study in minipigs to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Monkey / Non-human Primate Conduct a topical ocular toxicity study in monkeys/non-human primates to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Mouse Conduct a topical ocular toxicity study in mice to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Non-pigmented (New Zealand White; NZW) Conduct a topical ocular toxicity study in non-pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Rabbit, Pigmented (Dutch Belted, New Zealand Red) Conduct a topical ocular toxicity study in pigmented rabbits to determine the toxicity and toxicokinetic behavior of your compound.
  • Topical Ocular Toxicity and/or Toxicokinetic Study - Rat Conduct a topical ocular toxicity study in rats to determine the toxicity and toxicokinetic behavior of your compound.

Target Animal and Human Food Safety

  • Toxicity Test for Veterinary Drugs Use the drug at 10X the recommended dose for 3X the recommended duration to evaluate its safety.
  • Toxicokinetic Analysis Determine the drug concentration at which off-target or toxic effects occur.

Testing Services

  • Cosmetics Product Information File (PIF) audit Evaluate the cosmetics product information file which is a product dossier that contains all the most important information about the finished product.
  • Cosmetics safety assessments Conduct safety assessments such as Microbiological quality, Margin of Safety, and information about the packaging material of cosmetic products.
  • OECD 439: Skin Irritation Test (SIT) Reconstructed Human Epidermis Test (RhE) Method - An in vitro testing method designed to identify chemicals and/or mixtures capable of inducing moderate skin irritation.
  • Package Compatibility Tests Ensure that the consumer product is not adversely affected by the package components and vice versa.
  • Phototoxicology Phototoxicity testing identifies and evaluates the potential of chemical agents to induce toxicity upon subsequent exposure to light.

Other services

  • New Request &nbsp;

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • France PARIS 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

"Toxicology by design" Team of Eurotox experts
n°1 Market leader in compliance with PDE Cross Contamination monographs and ICH Q3D mostly in France and India

Professional associations
DCAT
Website
www.toxby.design

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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