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VectorBuilder
VectorBuilder is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country.
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Services
What this research supplier says it provides, as listed in the Scientist.com network.
Type of company: Mid sized business
Agricultural Sciences Research & Development
- Gene Isolation and cloning Development of methods for isolation of gene(s) of interest.
Antibodies
- Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
- Antibody Therapy Efficacy In vivo assessment of monoclonal/bispecific antibody efficacy in a humanized mouse
- Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
- Recombinant Antibody Production Request services related to antibody production services.
Cell Culture and Characterization
- Cell Line Construction Create new recombinant cell lines to exact specifications.
- Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
- Mycobacterium Screening Detect and distinguish between mycobacterium strains and species.
- Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
- Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.
Chemical and Compound Analysis
- Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
Chemistry, Manufacturing and Controls (CMC)
- Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
- Integrated Antibody Development Package-Europe Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
- Integrated Antibody Development Package-UK Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Show all 79 services
DNA & RNA
- cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
- cDNA library construction Generate a library of recombinant cDNA clones.
- Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
- CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
- DNA Library Screening Screen genomic or cDNA libraries for positive clones.
- DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
Show all 26 in DNA & RNA
- DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
- DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
- Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
- Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
- Genomic DNA cloning Clone and propagate genomic DNA inserts of 5-50kb.
- Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
- Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
- mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
- non-coding RNA Synthesis Prepare non-coding RNA in vitro.
- Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
- Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
- PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
- Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
- RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
- RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
- RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
- shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.
- siRNA Synthesis Produce high quality siRNAs for gene silencing studies.
- Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
- Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.
Human Biological Samples
- Cell Line and Cellular Services Promotion for Cells and Cell lines
- FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.
In Vitro Assays
- Antivirals Measure anti-viral activity in biochemical and cell assays.
- Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
- In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
- Microbiology Study microbes and their role in human health.
- Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.
- Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.
In Vitro Pharmacology
- High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
- Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
- Protein/Enzyme Targets For requesting Protein/Enzyme Targets
- Target Characterization Characterize potential drug targets during the drug discovery process.
- Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Pharmacology
- In Vivo Pharmacology Study the effects of drug candidates in animal models
Pharmacovigilance
- GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.
Product Orders
- Kits and Reagents Submit a request to multiple vendors for kits and reagents.
Protein Sciences
- Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
- Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
- Antimicrobial Peptide Synthesis Make a peptide with anti-microbial activities.
- Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
- ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
- Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Show all 22 in Protein Sciences
- Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
- Integrated Protein Production Package Process an entire Protein Production Pipeline Project including: Gene/Oligo Synthesis, Cloning/Subcloning, Protein Expression, Protein Purification, Protein Analysis, and Protein Products from our bundle of suppliers
- Lentivirus Production Develop lentiviruses and production protocols.
- Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
- Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
- Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
- Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
- Phage Display Use in vitro screening method to identify protein binding partners.
- Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
- Protein Expression In Plant Cells Express recombinant proteins in plant cells.
- Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
- Protein Products Find native and recombinant proteins and peptides.
- Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
- Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
- Virus Production Produce high titer viruses, viral expression vectors and vaccines.
- Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.
Other services
- New Request
Where it operates
Sites by country, with the cities in each.
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United States 1 site
About this supplier
In the supplier's own words, as listed in the Scientist.com network.
Custom vector construction, plasmid construction, virus packaging, BAC modification and recombineering, and cloning services.
- Website
- www.vectorbuilder.com
Work with VectorBuilder on Scientist.com
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