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VectorBuilder

VectorBuilder is listed as a mid sized business research supplier in the Scientist.com network, with 1 site in 1 country.

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Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Mid sized business

Agricultural Sciences Research & Development

  • Gene Isolation and cloning Development of methods for isolation of gene(s) of interest.

Antibodies

  • Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
  • Antibody Therapy Efficacy In vivo assessment of monoclonal/bispecific antibody efficacy in a humanized mouse
  • Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
  • Recombinant Antibody Production Request services related to antibody production services.

Cell Culture and Characterization

  • Cell Line Construction Create new recombinant cell lines to exact specifications.
  • Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.
  • Mycobacterium Screening Detect and distinguish between mycobacterium strains and species.
  • Recombinant Technology Manipulate genotypes to introduce or modify the expression of specific cell products or physical traits.
  • Viral Mediated Gene Delivery Use viral carriers to introduce new genetic material into a cell.

Chemical and Compound Analysis

  • Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample

Chemistry, Manufacturing and Controls (CMC)

  • Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services
  • Integrated Antibody Development Package-Europe Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
  • Integrated Antibody Development Package-UK Process an entire Antibody Development Pipeline Project including: Antigen Synthesis, Antibody Generation, Antibody Characterization, Antibody Modification, Antibody Purification, Antibody Products from our bundle...
Show all 79 services 65 more

DNA & RNA

  • cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.
  • cDNA library construction Generate a library of recombinant cDNA clones.
  • Cloning/Subcloning Clone or Subclone nucleotide sequence or gene.
  • CRISPR Using advanced CRISPR technology, add or delete base pairs at a specifically targeted DNA loci.
  • DNA Library Screening Screen genomic or cDNA libraries for positive clones.
  • DNA Mutagenesis Introduce insertions, deletions and substitutions into DNA clones.
Show all 26 in DNA & RNA 20 more
  • DNA Products Find DNA products including gDNA, cDNA clones, vectors and constructs from mice, insects, yeast, bacteria and viruses.
  • DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
  • Gene/Oligo Synthesis Synthesize oligonucleotide or gene for microarrays, RT-PCR and PCR cloning.
  • Genome Editing Use CRISPR, ZFN, TALEN or AAV gene targeting for targeted gene mutations and creation of transgenics.
  • Genomic DNA cloning Clone and propagate genomic DNA inserts of 5-50kb.
  • Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
  • Knockout/Knockin Cell Lines Develop Knockout/Knockin Cell Line.
  • mRNA synthesis Transcribe mRNAs in vitro and add modifications such as polyadenylation and guanine capping.
  • non-coding RNA Synthesis Prepare non-coding RNA in vitro.
  • Nucleic Acid Hybridization Use a nucleic acid probe to identify complementary sequences.
  • Oligo Synthesis Produce oligonucleotides for microarrays, RT-PCR and PCR cloning.
  • PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
  • Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.
  • RNA Interference Use small sequences of RNA that correspond to the targeted gene product to inhibit mRNA translation.
  • RNA oligo synthesis Design and synthesize miRNAs, siRNAs and other non coding RNAs
  • RNA Services Whether you’re isolating total RNA for whole genome expression analysis by microarray or setting up high content screening by s...
  • shRNA Synthesis Design shRNA constructs that produce stable knockdown of the corresponding mRNA.
  • siRNA Synthesis Produce high quality siRNAs for gene silencing studies.
  • Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
  • Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.

Human Biological Samples

  • Cell Line and Cellular Services Promotion for Cells and Cell lines
  • FRBESaHBS Request human biosamples including tissues, blood, serum, bone marrow, and tissue microarrays.

In Vitro Assays

  • Antivirals Measure anti-viral activity in biochemical and cell assays.
  • Endpoint Dilution Assay (TCID50) Assay Determine the viral titer to induce cell death in half the cell population of an inoculated tissue culture.
  • In Vitro Assay Development Develop innovative assay and screening methods outside a living organism to enable a wide range of pre-clinical activities.
  • Microbiology Study microbes and their role in human health.
  • Pathogen Assays Detect and distinguish viral, bacteria and fungal strains and species.
  • Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.

In Vitro Pharmacology

  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
  • Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
  • Protein/Enzyme Targets For requesting Protein/Enzyme Targets
  • Target Characterization Characterize potential drug targets during the drug discovery process.
  • Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.

Pharmacology

  • In Vivo Pharmacology Study the effects of drug candidates in animal models

Pharmacovigilance

  • GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Product Orders

  • Kits and Reagents Submit a request to multiple vendors for kits and reagents.

Protein Sciences

  • Adeno Associated Virus (AAV) Production Clone into AAV expression vectors and produce high titer viruses.
  • Antibody-Antigen Affinity Measurement Measure the binding kinetics of an antibody–antigen interaction.
  • Antimicrobial Peptide Synthesis Make a peptide with anti-microbial activities.
  • Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
  • ELISA Detect the presence of antigens recognized by antibodies or find antibodies that recognize an antigen.
  • Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
Show all 22 in Protein Sciences 16 more
  • Insect Expression Use baculovirus infected cells or non-lytic cell systems to produce glycosylated proteins.
  • Integrated Protein Production Package Process an entire Protein Production Pipeline Project including: Gene/Oligo Synthesis, Cloning/Subcloning, Protein Expression, Protein Purification, Protein Analysis, and Protein Products from our bundle of suppliers
  • Lentivirus Production Develop lentiviruses and production protocols.
  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
  • Peptide/Protein Based Vaccine Production Create a peptide or protein antigen for use in artificial immunization.
  • Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
  • Phage Display Use in vitro screening method to identify protein binding partners.
  • Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
  • Protein Expression In Plant Cells Express recombinant proteins in plant cells.
  • Protein Production Produce recombinant protein molecules in prokaryotic or eukaryotic systems.
  • Protein Products Find native and recombinant proteins and peptides.
  • Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
  • Virus Production Produce high titer viruses, viral expression vectors and vaccines.
  • Yeast Expression Amplify eukaryotic proteins that contain post translational modifications.

Other services

  • New Request  

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • United States Chicago 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Custom vector construction, plasmid construction, virus packaging, BAC modification and recombineering, and cloning services.

Website
www.vectorbuilder.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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