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Enzymlogic

Enzymlogic is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Biomarkers

  • Lipid Kinase Assays Use biochemical, cell-based or in vivo assays to measure lipid kinase activity.

Discovery Chemistry

  • Transporters Selectively screen for compounds with good permeability in the intestine, skin, or blood-brain barrier using drug transporter a...

In Vitro Assays

  • Assay Development Construct or create new assays or modify existing ones.
  • Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
  • HTS Assay Development Develop assays to use in high throughput screening.

In Vitro Pharmacology

  • Anaplastic lymphoma kinase (ALK) Assays Use biochemical, cell based or in vivo assays to measure ALK enzyme activity.
  • ATP Competitive Study Determine whether or not a compound is competitive with ATP.
  • Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
  • Extracellular signal Regulated Kinase Assays Use biochemical, cell based or in vivo assays to measure ERK enzyme activity.
  • Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.
  • G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
Show all 19 in In Vitro Pharmacology 13 more
  • High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
  • Human Epidermal growth factor Receptor (HER) Assays Use biochemical, cell based or in vivo assays to measure HER receptor activity.
  • In Vitro Enzyme Activity Assay Development Develop new in vitro enzyme activity assays or modify existing ones.
  • Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
  • Phosphatidylinositol 3-Kinase (PI3K) Assays Use biochemical, cell based or in vivo assays to measure PI3K enzyme activity.
  • Protein Kinase B (Akt) Assays Use biochemical, cell based or in vivo assays to measure Akt enzyme activity.
  • Raf Assays Use biochemical, cell based or in vivo assays to measure Raf enzyme activity.
  • Reversibility Study Determine whether or not a compound inhibits an enzyme reversibly.
  • Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
  • Substrate Competitive Study Determine whether or not a compound is competitive with a substrate.
  • Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
  • Vascular Endothelial Growth Factor (VEGF) Assays Use biochemical, cell based or in vivo assays to monitor competitive or non-competitive binding of VEGF ligand.
  • Vascular Endothelial Growth Factor Receptor (VEGFR) Assays Use biochemical, cell based or in vivo assays to measure VEGF receptor activity.

Protein Sciences

  • Fluorescence Polarization Investigate receptor-ligand interactions, protein-DNA interactions, proteolysis and membrane fluidity.
Show all 27 services 15 more

Other services

  • New Request  
  • Qube - High Throughput Screening Screen large compound libraries for ion channel blockers and modulators.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Spain Tres Cantos 1 site

Source: Scientist.com supplier network (site locations)

About this supplier

In the supplier's own words, as listed in the Scientist.com network.

Helping to select the best compounds Enzymlogic accelerates and improves the research productivity and effectiveness of its customer screening, lead optimization, Structure-Activity Relationship (SAR) and Structure-Kinetic Relationship (SKR) campaigns by its expertise and unique methodology for the discovery and development of new drugs. bq). Our services give you the data you need to make smart decisions sooner and help to optimize drugs with novel modes of binding. We combine kinetic and mechanistic information in order to: Promote efficient SAR and SKR Improve decision-making Enhance...

Show the full description

Helping to select the best compounds

Enzymlogic accelerates and improves the research productivity and effectiveness of its customer screening, lead optimization, Structure-Activity Relationship (SAR) and Structure-Kinetic Relationship (SKR) campaigns by its expertise and unique methodology for the discovery and development of new drugs.

bq). Our services give you the data you need to make smart decisions sooner and help to optimize drugs with novel modes of binding.

We combine kinetic and mechanistic information in order to:

  • Promote efficient SAR and SKR
  • Improve decision-making
  • Enhance drug’s clinical efficacy
  • Improve drug safety
  • Promote IP
  • Identify new therapeutic uses

Our drug discovery services:

  • Binding kinetics: Our proprietary method allows the rapid identification of compounds with the desired kinetic parameters as an efficient starting point for lead development and the parallel optimization of binding affinity (SAR) and binding kinetics (SKR).
  • Assay development: We apply enzymatic mechanistic principles to assay design in order to encourage the identification of inhibitors with novel modes of binding.

Click here to request further information on Enzymlogic's drug discovery services and partnering information. You can also email enquiries directly to Enzymlogic at [removed]

Find out more in our Services Brochure.

Website
www.enzymlogic.com

Source: Scientist.com supplier network, written by the supplier

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Sources: Scientist.com supplier network.

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