Bioascent

Bioascent is listed as a small business research supplier in the Scientist.com network, with 2 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 1

Type of company: Small business

Chemistry, Manufacturing and Controls (CMC)

Chemistry, Manufacturing and Controls (CMC) Request Chemistry, Manufacturing and Controls services

Discovery Chemistry

Compound Management Buy, maintain and process compound libraries, natural product libraries and building blocks.
Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Compound Synthesis Services (IP-sensitive) Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
Hit to Lead (H2L) Evaluate, perform limited optimization and identify small molecule hits from high throughput screens.
HTS Libraries Find targeted and broad collections of chemical compounds for high throughput screening and ADMET applications.

Show all 7 in Discovery Chemistry 1 more

Lead Optimization Perform chemical structural changes to improve preclinical drug candidate.

In Vitro Assays

Cell Based Assays Apply compounds to cells and test for cellular phenotypes and effects on gene expression
HTS Assay Development Develop assays to use in high throughput screening.
Luciferase Reporter Assay Evaluate promoter activity by measuring light output from the luciferase enzyme.

In Vitro Pharmacology

Anaplastic lymphoma kinase (ALK) Assays Use biochemical, cell based or in vivo assays to measure ALK enzyme activity.
ATP Competitive Study Determine whether or not a compound is competitive with ATP.
Dehydrogenase Assays Measure dehydrogenase activity in biochemical and cell-based assays.
Drug Target Assays Gain insight into the selectivity and mode-of-action of a compound's pharmacological targets.
Extracellular signal Regulated Kinase Assays Use biochemical, cell based or in vivo assays to measure ERK enzyme activity.
Fibroblast Growth Factor Receptor (FGFR) Assays Use biochemical, cell based or in vivo assays to measure FGF receptor activity.

Show all 28 in In Vitro Pharmacology 22 more

G-Protein Coupled Receptor (GPCR) Assays Detect ligand binding, receptor dimerization and downstream signal transduction events.
High Throughput Screening Conduct millions of chemical, genetic or pharmacological tests in a short period of time.
Histone Acetyltransferase (HAT) Assays Use biochemical, cell-based or in vivo assays to measure histone acetyltransferase activity.
Histone Deacetylase (HDAC) Assays Use biochemical, cell-based or in vivo assays to measure histone deacetylase activity.
Kinase Assays Measure activity of over 500 kinases in biochemical or cell-based assays.
Methyltransferase Assays Use biochemical, cell-based or in vitro assays to measure methyltransferase activity.
Nitric Oxide Synthase Assays Measure nitric oxide synthase activity by biochemical or cellular assays.
Nuclear Receptor Assays Measure nuclear receptor activity in biochemical and cell assays.
Oxidase Assays Use biochemical, cell-based or in vivo assays to measure oxidase activity.
Peroxidase Assays Measure peroxidase activity in bacterial and mammalian cells.
Phosphatase Assays Use biochemical, cell-based or in vitro assays to measure phosphatase activity.
Phosphatidylinositol 3-Kinase (PI3K) Assays Use biochemical, cell based or in vivo assays to measure PI3K enzyme activity.
Phosphodiesterase Assays Measure phosphodiesterase activity in biochemical and cell-based assays.
Protein Kinase B (Akt) Assays Use biochemical, cell based or in vivo assays to measure Akt enzyme activity.
Protein Targets Protein Targets are of pharmaceutical interest for drug discovery purposes.
Reversibility Study Determine whether or not a compound inhibits an enzyme reversibly.
Selectivity Profiling Determine the specificity of a ligand for its target by testing it against a large panel of related target proteins.
Substrate Competitive Study Determine whether or not a compound is competitive with a substrate.
Target Validation Demonstrate that modification of target activity has potential therapeutic benefits.
Time Dependent Study Determine whether or not a compound binds to an enzyme in a time-dependent manner.
Ubiquitin Ligase Assays Measure ligase enzyme activity in the presence of cofactors or chemical modifiers.
UDP-glucuronosyltransferases (UGT) Inhibition Assays Use biochemical, cell-based or in vivo assays to measure UDP-glucuronosyltransferase activity.

Website: www.bioascent.com

United Kingdom Newhouse, Lanarkshire 2 sites

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