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Giotto Biotech SRL

Giotto Biotech SRL is listed as a small business research supplier in the Scientist.com network, with 1 site in 1 country.

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Sites 1
Countries 1

Services

What this research supplier says it provides, as listed in the Scientist.com network.

Type of company: Small business

Biomarkers

  • Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
  • Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.

Chemical and Compound Analysis

  • Circular Dichroism Examine the secondary structure and folding properties of proteins in solution.
  • Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
  • High Resolution MS Elucidate the sequence and structure of peptides, proteins, biomarkers and organic compounds.
  • Ion Exchange Chromatography Separate and detect analytes.
  • Liquid Chromatography Separate substances using a mobile and stationary phase.
  • NMR Methods Use nuclear magnetic resonance spectroscopy to identify drug intermediates.
Show all 13 in Chemical and Compound Analysis 7 more
  • NMR Structure Determine molecular structure, identify chemical impurities and validate sample integrity.
  • Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
  • Size Exclusion Chromatography Separate and identify analytes based on their molecular size.
  • Solid State Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solid samples.
  • Solution Nuclear Magnetic Resonance Identify molecular structure or impurities and assess product integrity of solution samples.
  • Structure Determination Determine the three-dimensional structure of proteins in the presence or absence of ligands.
  • UV-Spectroscopy Conduct sample analysis based on light absorption and transmission.

Discovery Chemistry

  • Building Blocks Find chemicals used for creating new compound chemotypes and HTS libraries.
  • Compound Synthesis Synthesize small molecule candidates for use in hit followup, lead optimization and medicinal chemistry.
  • Custom Building Blocks Find or synthesize mg to kg amounts of chemical building blocks, scaffolds and reactive intermediates.
  • Impurity Synthesis Use high resolution MS or NMR to eliminate intermediates or organic byproducts and determine impurity content.
  • LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.
  • Stable Isotope Synthesis Label drug candidates with stable isotopes that simplify compound tracking and distribution studies.
Show all 36 services 22 more

DNA & RNA

  • PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
  • Plasmid DNA Preparation and Extraction Prepare plasmid DNA starting from E. coli cell pellets, transformed colonies or DNA samples.

In Vitro Pharmacology

  • Protease Assay Measure protease activity in biochemical and cell-based assays.

Protein Sciences

  • Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
  • Fusion Proteins Use recombinant DNA technology to create and express proteins derived from more than one gene.
  • Mammalian Expression Express high yields of recombinant proteins, antibodies, virus, viral-subunit proteins and gene-therapy vectors.
  • Peptide Synthesis Synthesize custom peptides that are long, have unusual modifications or are cyclic.
  • Peptide/Protein Products Purchase off-the-shelf protein or peptide products.
  • Protein Conjugation Create tagged monoclonals, polyclonal and recombinant proteins.
Show all 12 in Protein Sciences 6 more
  • Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
  • Protein Products Find native and recombinant proteins and peptides.
  • Protein Purification Isolate native or recombinant proteins from a sample.
  • Protein Services Consulting Expert advice to evaluate and analyze protein function and expression.
  • Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
  • Solid Phase Peptide Synthesis Create peptides on solid supports with reduced product loss.

Source: Scientist.com supplier network

Where it operates

Sites by country, with the cities in each.

  • Italy Sesto Fiorentino 1 site

Source: Scientist.com supplier network (site locations)

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Sources: Scientist.com supplier network.

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