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CER Groupe

CER Groupe is listed as a mid sized business research supplier in the Scientist.com network, with 4 sites in 1 country.

Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 4

Countries 1

Type of company: Mid sized business

Antibodies

Antibody Conjugation Conjugate an enzyme, biotin, or fluorophore to an antibody.
Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Antibody Humanization Increase an antibody's similarity to a variant produced naturally in humans.
Antibody Isotype Switching Modify antibody isotypes from any species to any human IgG isotype.
Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.

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Antibody Sequencing Sequence cDNA encoding variable heavy (VH) and variable light (VL) domains of a hybridoma cell line.
Biotin-Antibody Conjugation Biotinylate an antibody for improved detection.
Hybridoma Sequencing/Antibody Sequencing Determine the sequences of monoclonal antibodies.
In Vitro Monoclonal Antibody Production Generate monoclonal antibodies in vitro using cultured antibody-secreting hybridoma cell lines.
Phosphospecific Antibodies Create antibodies to detect phosphorylated protein targets.
Polyclonal Antibody Production Generate polyclonal antibodies in vivo using evolutionary distant animal species.
Polyclonal/Monoclonal Antibody Production Generate polyclonal or monoclonal antibodies in a range of animal species, over-express antibodies in cultured cells.
Single Chain Variable Fragment (scFv) Create an antigen-specific antibody derivative using a linker to join a heavy and a light variable chain.

Bioimaging

In Vivo Imaging In-vivo imaging using PET, MRI, CT etc.
In Vivo Whole Tissue and Animal Imaging Analysis Analysis of images from in vivo studies produced using PET, MRI, CT, etc. in a variety of species.
In-vivo Fluorescence In-vivo fluorescence enables visualisation and the study of biological processes in live organisms by using fluorescent markers.

Biomarkers

Cell Viability Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Immunoassays Create antibody-based assays for the identification and quantification of specific antigens.
Immunophenotyping Separate cell types based on their expression of biomarkers or based on their individual and unique expression patterns.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.

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Cell Culture and Characterization

Bacterial Cell Culture Culture and Grow bacterial cells.
Cell Culture Culture primary or immortalized cell lines.
Cell Line Construction Create new recombinant cell lines to exact specifications.
Cell Transfection Produce, package and optimize transfection of your siRNA or DNA construct.

Chemical and Compound Analysis

Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Immunoaffinity Chromatography Use antibody-antigen interactions to isolate and concentrate analytes.
Ion Exchange Chromatography Separate and detect analytes.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.
Size Exclusion Chromatography Separate and identify analytes based on their molecular size.

Clinical Trials

Pharmacokinetic Studies Design a study that observes the time course of drug absorption, distribution, metabolism, and excretion, as means to test the safety and effective therapeutic management of drugs in an individual patient.

Data Science/Bioinformatics

In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.

Developmental and Reproductive Toxicology (DART)

Juvenile Toxicity Study - Rat Conduct a study to determine the differences in toxicity between immature and mature systems in rats.

Disease Models

Arthritis Models Measure therapeutic endpoints in animal models of arthritis.
Bacterial Infection Models Measure therapeutic endpoints in animal models of bacterial infection.
Blood Models Test for therapeutic efficacy of drug candidates in blood disorder models.
Bone Models Measure therapeutic endpoints in animal models of bone disorders.
Cartilage Repair Models Measure therapeutic endpoints in animal models of cartilage repair.
General Pain Models Measure therapeutic endpoints in animal models of general pain.

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Inflammation Models Measure therapeutic endpoints in animal models for inflammation.
Liver Fibrosis Models Measure liver fibrosis using therapeutic endpoints such as collagen assessment, TUNEL staining and inflammatory markers.
Microsurgery in Rodents Outsource microsurgeries projects required for testing new therapies on a rodent model.
Non Obese Diabetic Mice Use a single animal species to create one or more disease models for diabetes.
Osteoarthritic Pain Models Measure therapeutic endpoints in animal models of osteoarthritic pain.
Osteoarthritis Models Measure therapeutic endpoints in animal models of osteoarthritis.
Osteoporosis Models Measure therapeutic endpoints in animal models of osteoporosis.
Pain Endpoints Models Measure therapeutic endpoints in animal models of pain.
Pain Model Consulting Expert advice to better evaluate and understand pain thresholds and phenomena within living organisms. Can be used to evaluate pain associated with specific diseases or injuries affecting the sensory and nervous systems.
Pain Models Test therapeutic efficacy of drug candidate in pain model.
Respiratory Models Test therapeutic efficacy of drug candidate in respiratory disease model.
Xenografts Evaluate drug candidate in tissue graft or organ transplant model.

DNA & RNA

Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
DNA Sequencing Determine the nucleotide sequence of DNA samples.
DNA Synthesis Produce DNA fragments for microarrays, PCR, cloning and expression studies.
PCR Mutagenesis Use polymerase chain reaction to create mutations in a cloned gene.
qPCR Analysis Measure the accumulation of PCR products in real time.
Quantitative RT PCR Use quantitative reverse transcription polymerase chain reaction to measure absolute and relative mRNA abundance.

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RNA Extraction Isolate total RNA or mRNA from cells or tissues

Drug Development

Assay Development Consulting Request consultant services measuring the activity of a drug or biochemical in an organism or organic sample.
Consulting Services Work with consultants who provide expert advice in various areas of research and technology.
Pharmacology Consulting Request consulting services related to pharmacology and the chemical properties, biological effects, and therapeutic uses of drugs.
Safety Pharmacology Consulting Consulting services that help with the detection of potential undesirable pharmacodynamic effects of chemical entities on physiological functions.
Small Molecule Drug Development Consulting Request consulting services related to small molecule development.
Toxicology Consulting Use models to assess acute and sub-acute toxicity as well as chronic and sub-chronic toxicity.

General in vivo Toxicology

IV Toxicology Test the toxicological effect of IV delivery of drug candidate.
Nonclinical Study Management Provide nonclinical study management services to pharmaceutical and biotech companies. The services can be customized to meet the clients needs.
Oral Toxicology Use toxicity studies in animals to evaluate the oral toxicity of a drug candidate.
Repeat Dose Toxicity Study - Other Species Conduct a repeat dose study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Toxicity Study - Rat Conduct a repeat dose study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Short-Term Toxicity Tests Acquire preliminary data about the concentrations, exposure duration and effects of a toxin on organisms.

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Single Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by a single administration in a 7 day period.
Single Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by a single administration in a 7 day period.

In Vitro ADME

Cell Fractionation Isolate organelles and subcellular components.

In Vitro Assays

Cell Proliferation Measure cell number, cell viability and cell division.
Cytometric Bead Array (CBA) FACS Analysis Use flow cytometry and antibody-coated beads to simultaneously detect multiple target proteins.
In Vitro Efficacy Test Use in vitro models to test the efficacy of your products.

In Vitro Pharmacology

In Vitro Disease Models Screen pre-clinical candidates without the use of live animals.

In Vitro Toxicology

ADCC and CDC Assay Services Measure toxicity of antibodies.
Cytotoxicity Test for effects on cell viability and proliferation

In Vivo ADME

Chronic Bile Duct Cannulation (BDC) Study - Other Species Conduct a bile duct cannulation (BDC) study in other species to support the absorption, distribution, metabolism and excretion profiling of your compound.

In Vivo Pharmacokinetics

In Vivo Immunogenicity Study An in vivo immunogenicity study evaluates a substance's ability to trigger an immune response within a living organism.
In Vivo Pharmacokinetics Run pharmacokinetic studies in animals that measure a drug's absorption, distribution, metabolism and excretion (ADME).
In Vivo PK Consulting Expert advice on pharmacokinetics and how specific drugs affect the body to determine function, effectiveness, dosage size, etc…
Integrated In Vivo Services Package Process an entire In Vivo Project including: Dose Formulation, PK Screening, ADME-Profiling, Toxicology, Safety Pharmacology, DART, IND Filing from our bundle of suppliers.
Maximum Tolerated Dose (MTD) Studies Determine Maximum Tolerated Dose (MTD) of a drug candidate in either a single or repetitive dosing study in a rodent (typically mouse or rat).
Mouse Efficacy Monotherapy Use mouse models to determine the anti-cancer efficacy of a drug candidate compared to a positive control.

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Pharmacokinetic (PK) Screening - Minipig Run pharmacokinetic studies in minipigs that measure a drug’s absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Mouse Run pharmacokinetic studies in mice that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Other Species Run pharmacokinetic studies in large animals that measure a drug's absorption, distribution, metabolism and excretion.
Pharmacokinetic (PK) Screening - Rat Run pharmacokinetic studies in rats that measure a drug's absorption, distribution, metabolism and excretion.
Repetitive Maximum Tolerated Dose (MTD) Mouse Study Use mouse models to determine the MTD of a drug candidate by repetitive administrations for 7 days.
Repetitive Maximum Tolerated Dose (MTD) Rat Study Use rat models to determine the MTD of a drug candidate by repetitive administrations for 7 days.

Lab Supplies, Facilities, and Equipment

Biobanking Store and track biological samples.

Model Development

Animal Model Development Create new systems for profiling pre-clinical therapeutics, devices, and surgical techniques.
Lewis Rat Use a single animal species to create one or more disease models for metastatic cancer, hematopoiesis and anemia.
NMRI Mouse Use a single animal species to create one or more disease models for cachexia and hemophilia.
PBMC Humanized Mice Study and evaluate compounds for infectious diseases and graft rejection.
SCID Mouse Use a single animal species to create one or more disease models for spontaneous and metastatic cancer and cachexia.
SCID/BG Mouse Use a single animal species to create one or more disease models for metastatic cancer.

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Sprague Dawley Rat Use a single animal species to create one or more disease models for cachexia.

Non-Human Biospecimen

Rabbit Biofluids Acquire fresh or frozen biofluids including but not limited to whole blood, plasma, serum, CSF, milk, urine, feces, bile, semen, aqueous humor, vitreous humor, saliva, tears, etc.

Oncology Models

Athymic Mouse Use a single animal species to create one or more disease models for cachexia and spontaneous cancer.
NCG Model Study tumor biology and immuno-oncology in the CRISPR/Cas9-generated immunodeficient mouse model.
Oncology Xenografts Xenografts derived from oncological samples.

Pharmacology

In Vivo Pharmacology Study the effects of drug candidates in animal models

Protein Sciences

Bacterial Expression Produce milligram, gram and kilogram amounts of proteins.
Cytokines Find recombinant cytokines or cytokine assays.
LCMS/MS Analysis Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.
Protein Expression Produce recombinant proteins in prokaryotic or eukaryotic systems.
Protein Identification Uncover or confirm the identity of a protein.
Protein Purification Isolate native or recombinant proteins from a sample.

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Recombinant Proteins Use recombinant DNA to produce proteins in vivo or in vitro.
Virus Production Produce high titer viruses, viral expression vectors and vaccines.
Western Blots Detect specific proteins in a sample of tissue homogenate or extract.

REACH Services

OECD 407: Repeated Dose 28-day Oral Toxicity Study in Rodents This method provides information on health hazard likely to arise from exposure to test substance via oral administration.
OECD 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents This method provides information on health hazard likely to arise from exposure to test substance via oral administration.
OECD 425: Acute Oral Toxicity: Up-and-Down Procedure The method permits estimation of an LD50 with a confidence interval and the results allow a substance to be classified for acute toxicity according to the Globally Harmonised System of classification and labelling...
OECD 452: Chronic Toxicity Studies Evaluate the direct and indirect impact of prolonged and repeated toxin exposure to test organisms.

Safety Pharmacology

Jacketed External Telemetry (JET) Study - Other Species Conduct a study that allows the continuous collection of cardiovascular data following dosing of your compound in other species.
Locomotor Activity Assessment Study - Rat Conduct a study to determine the psychostimulant or sedative activity or your compound in rats.
Safety Pharmacology Assess the impact of a therapeutic for human use on vital organ systems before first-in-man drug testing.

Specialty Dosing Routes

Chronic Intravenous Infusion Carcinogenicity Study - Rat Conduct a repeat intravenous infusion dose, chronic carcinogenicity study in rats to determine the tendency of your compound to produce tumors.
Repeat Dose Intranasal Study - Mouse Conduct a repeat dose intranasal study in mice to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intranasal Study - Other Species Conduct a repeat dose intranasal study in other species to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intranasal Study - Rat Conduct a repeat dose intranasal study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Repeat Dose Intravenous Infusion Study - Rats Conduct a repeat dose intravenous infusion study in rats to determine the toxicity and toxicokinetic behavior of your compound.
Single Dose Acute Intranasal Study - Mouse Conduct a single dose intranasal study in mice to determine the toxicokinetic behavior of your compound.

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Single Dose Acute Intranasal Study - Other Species Conduct a single dose intranasal study in other species to determine the toxicokinetic behavior of your compound.
Single Dose Acute Intranasal Study - Rat Conduct a single dose intranasal study in rats to determine the toxicokinetic behavior of your compound.
Topical Dermal Toxicity and/or Toxicokinetic Study - Minipig Conduct a dermal study to determine the toxicity and/or toxicokinetic behavior of your compound when applied topically to minipigs.

Other services

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Belgium Marche-en-Famenne 4 sites

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CER Groupe is an Accredited Research Centre active in Life Sciences fields. With more than 40 years of experience, highly qualified staff and modern facilities, the CER Groupe focuses its expertise on agricultural and veterinary sciences, food safety, biotechnologies and biomedical research. Due to its high quality work, the CER Groupe has become National Reference Laboratory (NRL) in several areas.
Today, through its three highly interconnected lines of activities – preclinical, bioproduction, and diagnostic – the CER Groupe offers a complete and innovative panel of services and expertise, and collaborates with many public and private partners.
Furthermore, the CER Groupe is certified at the highest levels required in those fields, ensuring its partners and customers the best services and products according to their needs.
The CER Groupe, key partner for all your pioneering projects!
• Preclinic
◦ Development and validation of preclinical models in cell therapy, cancerology, infectiology and immunology (small animals in SPF A2 and A3 facilities and large animals)
◦ Custom-tailored solution to your studies (residues, bioequivalence, metabolism, toxicity, tolerance, innocuity, efficacy, teratogenicity, test release, microsurgery, ...) in SPF and/or GLP facilities
• Bioproduction
◦ Antibodies development, upstream and downstream processing (monoclonal, polyclonal, chimerized, humanized), also in ISO facilities
◦ Proteins studies, design, upstream and downstream processing (native or recombinant)
◦ Biobanking and bioproduction (cell lines, virus, BL3 and BL2 pathogens, ...)
• Diagnostic
◦ Development and Validation of LC and GC-MS/MS, ELISA and PCR assays
◦ Diagnosis kit production (animal diseases, veterinary drug residues and allergens detection in foodstuffs, feed and biological samples)
◦ Belgian National Reference Laboratory (food allergens, marine toxins, veterinary drugs, fish diseases)

Website: www.cergroupe.be

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