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Medicover Integrated Clinical Services

Medicover Integrated Clinical Services is listed as a mid sized business research supplier in the Scientist.com network, with 2 sites in 2 countries.

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Search companies, drugs, suppliers and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.

Sites 2

Countries 2

Type of company: Mid sized business

Antibodies

Antibody Detection Quantitate, localize and visualize proteins and other antigens.
Antibody Products Purchase antibody, antibody pair kit or ELISA kit.
Antibody Purification Purify multiple antibody types including IgG, IgM, IgA and IgY.

Biomarkers

Autoantibody Testing Screen for the presence of an autoimmune disorder.
Basic Metabolic Profiling Set up assays that monitor drug metabolite formation after administration of drug to an animal model or patient.
Biomarker Analytical Validation Assess and optimize the characteristics of a candidate biomarker to ensure reproducibility and consistency.
Biomarker Clinical Utility Evaluate the potential clinical applications of a candidate biomarker.
Biomarker Clinical Validation Evaluate the predictive ability of a candidate biomarker for a disorder.
Biomarker Discovery Identify a biomarker associated with disease progression of disease, effectiveness of therapy or diagnosis of disease or condition.

Show all 37 in Biomarkers 31 more

Biomarker Services Evaluating normal/abnormal biological conditions and characteristics within the body
Cell Membrane Lipidomics Study the pathways and networks of membrane lipids.
Cerebrospinal Fluid Analysis Use CSF to detect or monitor a variety of nervous system diseases or conditions.
Clinical Chemistry Measure analytes in serum, plasma, cells, tissue lysates or other biological materials.
Complete Metabolic Panel Testing Detect electrolyte or glucose imbalance to identify or monitor related disorders.
Cytogenetics Examine the structure and function of the cell, especially chromosomes.
Cytokine Release Assay Use in vivo or in vitro assays to detect unregulated or excessive release of pro-inflammatory cytokines.
Diagnostic Biomarkers Discovery Identify candidate biomarkers indicative of the presence of a disorder.
Endocrine Assays Use biochemical, cell based or in vivo assays to measure the concentration of hormones.
Epigenetics Epigenetics sits at the cutting edge of drug discovery. The ability to modify genomes without changing any sequences with methylation.
Flow Cytometry Identify fluorescently-labeled cells or physically separate cells from a larger population using biomarkers.
Fluorescent In Situ Hybridization Use FISH to identify abnormal chromosome structures and to quantify specific DNA sequences.
Human Primary Cell Isolation Isolate primary cells from various human tissues.
Immunohistochemistry Examine the toxic effects of pre-clinical compounds in small animal and patient histological samples.
Immunostaining Use labeled antibodies to detect proteins or other antigens in cells or tissues.
Insulin Autoantibodies (IAA) Testing Detect the risk or presence of type 1 diabetes in early childhood.
Interferon Gamma Release Assay Use in vivo or in vitro assays to measure the cell-mediated immune response to an infectious agent.
Lipid Profiling Use quantitative analysis of blood lipid components to assess cardiac risk.
Lipoprotein Associated Phospholipase A2 Testing Assess vascular inflammation and determine the risk for atherosclerosis or arterial plaque rupturing.
Metabolomics Biomarker Discovery Identify and quantitate metabolite biomarkers in blood, urine, CSF and bodily fluids.
Microbiome Services Examine the community of commensal, symbiotic, and pathogenic microorganisms that make up the microbiome.
Osteoclasts Measure osteoclast activity and bone resorption in human, mouse or rat assays.
Paraffin-based Histology Perform sectioning and histological analysis of wax-embedded samples.
Pharmacodynamic Biomarkers Discovery Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Platelet Function Testing Evaluate complete platelet function in vivo or in vitro.
Predictive Biomarkers Discovery Identify candidate biomarkers suggestive of a response to a treatment.
Single Cell Isolation Isolate single cells for subsequent single-cell analysis.
Single Cell Transcriptome Sequencing Detect distinct, rare or abnomal cell types in a heterogenous population.
Special Stainings Use a variety of techniques for the selective visualization of specific tissue or cell types.
Stem Cell Analysis Assess hematopoietic, neural and mesenchymal cell progenitor proliferation and differentiation.
T Cell Epitope Characterization Evaluate the potency and immunodominance of T-cell epitopes within a molecule.

Cell Culture and Characterization

Bacterial Cell Culture Culture and Grow bacterial cells.
Cell Culture Culture primary or immortalized cell lines.
Cryo-based Histology Perform sectioning and histological analysis of frozen non-fixed samples.
Karyotyping Evaluate the number and appearance of chromosomes in the nucleus of a eukaryotic cell.
Microsatellite Instability Analysis Compare allelic profiles and detect genomic instability.
Single Cell DNA Sequencing Examine genetic variations in a single cell.

Show all 7 in Cell Culture and Characterization 1 more

Spectral Karyotyping Identify chromosomal abnormalties often not detected by traditional methods.

Show all 140 services 125 more

Chemical and Compound Analysis

Amino Acid Analysis (AAA) Determine protein quantities, relative compositions and amino acid content profiles.
Denaturing High Performance Liquid Chromatography Separate mixtures of denatured and reannealed oligos to identify single nucleotide substitutions, deletions and insertions.
Electrophoresis Separate nucleic acids or proteins based on physical properties such as charge or mass.
Endotoxin Testing Use standard assays like LAL (Limulus Amebocyte Lysate), rFC (Recombinant Factor C), or MAT (Monocyte Activation Test) to detect and quantify the level of endotoxins in a sample
GLP Large Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of large biomolecules.
GLP Small Molecule Bioanalysis Detect and analyze the pharmacokinetic profile of small molecules.

Show all 8 in Chemical and Compound Analysis 2 more

Liquid Chromatography Separate substances using a mobile and stationary phase.
Protein Separation and Detection Separate proteins based on properties such as solubility, adsorption or size differences.

Chemical and Compound Testing

Clinical Pathology Diagnose disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissues.
Product Testing Ensure product quality standards are met.

Clinical Consulting

Biomarker Services Consulting Expert advice to conduct solutions for evaluating normal/abnormal biological conditions and characteristics within the body.

Clinical Trials

Central Laboratory Services A centralized facility that handles the processing and analysis of samples collected from multiple sites in a study.

Data Science/Bioinformatics

Discovery Statistical and Mathematical Modeling Use mathematical variables and equations to establish relationships between data.
In Silico Cancer Genomics/Cancer Transcriptomics Analysis Interpret DNA sequencing and microarray data for cancer studies.
In Silico Epigenetic Compound Library Screening Use computer-aided methods to discover new compounds against key regulators of epigenetic signaling.
In Silico Protein Microarray Analysis Use software to visualize and evaluate protein function and expression on a large scale.
In Silico Protein Sequence Analysis Use software to predict protein structural and functional features and secondary structure components.

Discovery Chemistry

In Silico Lead Optimization Use in silico design to enhance the ADME-PK properties of candidate drugs to maximize efficacy and safety.
LCMS Analysis Physically separate substances using liquid chromatography and mass spectrometry.

DNA & RNA

Amplicon - HLA Typing Use an amplicon sequencing method to identify allelic variation within the HLA genes.
Amplicon 16s rRNA Sequencing Identify and compare bacteria present within a given sample.
Amplified Fragment Length Polymorphism Detection Detect DNA polymorphisms based upon restriction enzyme digestion and PCR.
Bisulfite Sequencing (RRBS) Analyze genome-wide methylation profiles on a single nucleotide level.
Capillary Electrophoresis Separate ng quantities of DNA to single base resolution.
cDNA cloning & subcloning Move cDNA fragments between different cloning vectors.

Show all 39 in DNA & RNA 33 more

Cell Free DNA Assay Detect known mutations and discover new ones in cell-free plasma DNA.
ChIP-Sequencing Use chromosome immunoprecipitation to identify DNA-protein binding sites in a genome.
ChIP-sequencing Profiling Identify where a protein is binding to DNA on a genome-wide scale.
Chromatin Interaction Analysis-Paired End Tag Sequencing Sequence DNA using Chromatin Conformation Capture (3C) together with Chromatin Immunoprecipitation (ChIP).
Digital Polymerase Chain Reaction Obtain improved absolute target quantification and rare allele detection compared to conventional qPCR.
DNA Hydroxy Methylation Seq Use epigenetic services to analyze genome-wide DNA hydroxymethylation.
Exome Sequencing Determine protein-coding nucleotide sequences in a DNA sample.
Expression Profiling Measure the the expression of thousands of genes at once to create a global picture of cellular function.
Genomic DNA Purification Isolate genomic DNA from cells or tissue samples.
Genotyping Examine a DNA sequence to identify specific genetic varients .
Metagenomic Sequencing Sequence genetic material recovered directly from environmental samples
Methylation Analysis Determine genomic methylation patterns and analyze methylation in tumors and treated samples.
Methylation Specific PCR Determine the methylation status of a CpG site without the need for base-specific endonucleases.
mtDNA Sequencing Use next-generation sequencing (NGS) technology to detect and analyze mitochondrial mutations.
Multiplex Cellular miRNA Assay Use Firefly™ technology for multiplex cellular microRNA profiling.
NGS: Next Generation Sequencing Sequence millions of template DNA molecules in parallel.
qPCR Analysis Measure the accumulation of PCR products in real time.
RAD Sequencing Examine a small percentage of the target genome.
Restriction Fragment Length Polymorphism Identification Uses gel electrophoresis to identify differences in restriction fragment lengths produced by enzymatic digestion of DNA.
RNA Profiling Quantify the expression levels of mRNA transcripts, enabling the determination of gene expression patterns.
Sanger Sequencing Sequence single strand DNA fragments using DNA Polymerase.
Sequence Based Methylation Analysis Detect DNA methylation sites within cytosine-phosphate-guanine (CpG) dinucleotides at single base-pair resolution.
Single Cell RNA Sequencing Quantify mRNA variants in a single cell.
Single Molecule Real Time Sequencing Monitor the incorporation of fluorescently conjugated nucleotides within zero-mode waveguide (ZMW) chambers.
SNP Characterization Identify single nucleotide polymorphisms to make genetic associations, analyze disease SNPs and determine LOH.
Target Gene Expression Measure expression of a target gene at the protein, RNA and DNA level.
Targeted Bisulphite Sequencing Reveal changes in DNA methylation associated with nuclear reprogramming.
Targeted Sequencing/Resequencing Detect variations in a genome subset.
Tissue Microarray Screen large numbers of tissues for the presence or absence of specific molecular markers.
Whole Genome Amplification (WGA) Amplify an entire genome from a single cell.
Whole Genome Bisulphite Seq Profile genome-wide DNA methylation.
Whole Genome Profiling Develop sequence-based physical maps for the assembly of genomes.
Whole Genome Sequencing Determine the entire genetic make-up of an organism.

Human Biological Samples

HBS Chronic Obstructive Pulmonary Disease (COPD) Acquire fresh, frozen, or fixed COPD tissue or for requesting other COPD human biospecimen samples.
HBS Diabetes For requesting HBS Diabetes.
HBS Healthy/Controls For requesting HBS Healthy/Controls
HBS Leukemia For requesting HBS Leukemia
HBS NSCLC For requesting HBS NSCLC
HBS Oncology For requesting Human biospecimens from Oncology indications

Show all 11 in Human Biological Samples 5 more

Human Blood Acquire fresh/frozen human blood based on patient demographics, disease stage, history and treatment.
Human Fixed Tissue Acquire Human fixed tissue based on patient demographics, disease stage, history and treatment.
Human Fresh Tissue For requesting fresh human tissue
Human Frozen Tissue For requesting frozen human tissue.
Human Plasma Acquire fresh/frozen human plasma

In Vitro ADME

Metabolite Identification and Profiling Estimate drug candidate metabolites after administration of drug to an animal or human subject.
Plasma Stability Assay Determine degradation rate of drug candidates in plasma.

In Vitro Assays

Annexin V Apoptosis Assay Detect and quantify apoptotic cells based on loss of membrane asymmetry.
Apoptosis Assays Detect apoptotic events that lead to programmed cell death.
Biosensor Assays Evaluate biological activity of new compounds, detect toxic metabolites or monitor biomarkers.
Glucose Release Assay Determine free glucose levels in biological samples.
Hydroxyproline Assays Use biochemical, cell based or in vivo assays to quantify hydroxyproline or collagen in a sample.
Lipid Detection Use in vitro methods to identify lipid droplets and any associated proteins.

Show all 12 in In Vitro Assays 6 more

Lipolysis Measure the hydrolysis of triglycerides into glycerol and free fatty acids.
Oxidative Burst Examine the release of reactive oxygen species (ROS) from neutrophils and other immune cells.
Serine Protease Assay Detect apoptosis by measuring protease activity.
Thrombin Generation Tests Measure the tendency of a plasma sample to form thrombin upon the initiation of coagulation.
Virus Detection Assays Use ultra-sensitve methods to reliably detect low level viruses.
Von Willebrand Factor Analysis Detect and classify the Von Willebrand disease sub-type.

In Vitro Toxicology

Cytotoxicity Test for effects on cell viability and proliferation

Lab Supplies, Facilities, and Equipment

Biobanking Store and track biological samples.

Other Specialty Toxicology

Microdilution Testing Simultaneously quantify the susceptibility of a microbial species or strain to multiple anti-microbial agents.

Pharmacovigilance

GxP Compliance Monitoring Ensure products or services adhere to a set minimum standard.

Protein Sciences

Cytokines Find recombinant cytokines or cytokine assays.
Protein Purification Isolate native or recombinant proteins from a sample.
Proteomics Do large-scale experimental analysis of proteins focused on understanding structure and function.
Surface Plasmon Resonance (SPR) Measure interactions of biomolecules including antibodies, vaccines, biomarkers and small molecules.

Scientific Data Services

Database Integration Convert bioinformatics results from multiple data sources (DSs) into a single operational format.
In Silico Genomics/Transcriptomics Data Analysis Interpret DNA sequencing and microarray data.

Website: medicover-mics.com

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Poland Gdańsk 1 site

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